coagulation factor VII (Q412850)

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mammalian protein found in Homo sapiens
  • F7
  • proconvertin
  • eptacog alfa
  • FVII coagulation protein
  • Serum prothrombin conversion accelerator
  • coagulation factor VII
  • SPCA
  • coagulation factor VII (serum prothrombin conversion accelerator)
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Language Label Description Also known as
English
coagulation factor VII
mammalian protein found in Homo sapiens
  • F7
  • proconvertin
  • eptacog alfa
  • FVII coagulation protein
  • Serum prothrombin conversion accelerator
  • coagulation factor VII
  • SPCA
  • coagulation factor VII (serum prothrombin conversion accelerator)

Statements

part of
molecular function
protein binding
determination method
IPI
7 references
retrieved
8 April 2019
stated in
Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IPI
retrieved
8 April 2019
stated in
The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IPI
retrieved
8 April 2019
stated in
Factor VII central. A novel mutation in the catalytic domain that reduces tissue factor binding, impairs activation by factor Xa, and abolishes amidolytic and coagulant activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IPI
retrieved
8 April 2019
stated in
Factor VII deficiency caused by a structural variant N57D of the first epidermal growth factor domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IPI
retrieved
8 April 2019
stated in
Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IPI
retrieved
8 April 2019
stated in
Affinity purification of human tissue factor: interaction of factor VII and tissue factor in detergent micelles
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IPI
cell component
biological process
blood coagulation
determination method
IEA
IDA
TAS
6 references
retrieved
24 April 2018
stated in
Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08709&geneProductId=UniProtKB:P08709
determination method
TAS
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P08709
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08709&geneProductId=UniProtKB:P08709
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08709&geneProductId=UniProtKB:P08709
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08709&geneProductId=UniProtKB:P08709
determination method
IEA
retrieved
24 April 2018
stated in
MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08709&geneProductId=UniProtKB:P08709
determination method
IDA
retrieved
24 April 2018
stated in
Structural integrity of the gamma-carboxyglutamic acid domain of human blood coagulation factor IXa Is required for its binding to cofactor VIIIa
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08709&geneProductId=UniProtKB:P08709
determination method
IDA
blood coagulation
determination method
IBA
IDA
IEA
TAS
7 references
retrieved
8 April 2019
stated in
Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08709
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IEA
retrieved
8 April 2019
stated in
Structural integrity of the gamma-carboxyglutamic acid domain of human blood coagulation factor IXa Is required for its binding to cofactor VIIIa
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IDA
retrieved
8 April 2019
stated in
MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08709
determination method
IBA
Gene Atlas image
PBB GE F7 207300 s at fs.png
732 × 530; 10 KB
0 references
Commons category
Coagulation factor VIIa
0 references

Identifiers

ATC code
B02BD05
0 references
PDB structure ID
 
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