Methylation status at HYAL2 predicts overall and progression-free survival of colon cancer patients under 5-FU chemotherapy (Q41239086)

28 September 2017

Methylation status at HYAL2 predicts overall and progression-free survival of colon cancer patients under 5-FU chemotherapy (English)

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28 September 2017

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Jenny Chang-Claude

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Barbara Burwinkel

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Michael Hoffmeister

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Michael Hoffmeister

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Cornelia M. Ulrich

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Cornelia M Ulrich

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28 September 2017

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Esther Herpel

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Hendrik Bläker

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Alexis Ulrich

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Axel Benner

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Katrin Pfütze

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28 September 2017

Rongxi Yang

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7 October 2015

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28 September 2017

Cancer statistics, 2008

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2015.10.002

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Cancer statistics, 2015

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Molecular heterogeneity of colorectal cancer: Implications for cancer control

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Adjuvant therapy in colon cancer

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American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer

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Postoperative adjuvant chemotherapy for stage II colorectal cancer: a systematic review of 12 randomized controlled trials

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Genomic and epigenomic integration identifies a prognostic signature in colon cancer

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Predicting clinical outcome of 5-fluorouracil-based chemotherapy for colon cancer patients: is the CpG island methylator phenotype the 5-fluorouracil-responsive subgroup?

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Genetic prognostic and predictive markers in colorectal cancer

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Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

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Cancer epigenomics: DNA methylomes and histone-modification maps

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HYAL2, a human gene expressed in many cells, encodes a lysosomal hyaluronidase with a novel type of specificity

7 January 2021

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Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines

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Angiogenic oligosaccharides of hyaluronan induce multiple signaling pathways affecting vascular endothelial cell mitogenic and wound healing responses

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Hyaluronan: from extracellular glue to pericellular cue.

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Involvement of hyaluronidases in colorectal cancer

7 January 2021

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The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

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DNA methylation array analyses identified breast cancer-associatedHYAL2methylation in peripheral blood

7 January 2021

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S100P and HYAL2 as prognostic markers for patients with triple-negative breast cancer

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Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption

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Protection from colorectal cancer after colonoscopy: a population-based, case-control study.

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Gene selection in microarray survival studies under possibly non-proportional hazards.

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A note on quantifying follow-up in studies of failure time

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DNA methylation profiling in the clinic: applications and challenges

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Methylation of the polycomb group target genes is a possible biomarker for favorable prognosis in colorectal cancer

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SPARC and DNA methylation: possible diagnostic and therapeutic implications in gastrointestinal cancers.

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Pharmacogenetics and diseases of the colon

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Genetic and epigenetic biomarkers for diagnosis, prognosis and treatment of colorectal cancer

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Promoter hypermethylation of tumour suppressor genes as potential biomarkers in colorectal cancer

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Proteomic profiling of paraffin-embedded samples identifies metaplasia-specific and early-stage gastric cancer biomarkers

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DNA methylation based biomarkers: practical considerations and applications

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Hyal2--less active, but more versatile?

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Microsatellite instability and colorectal cancer prognosis.

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Chromosomal aberrations and gene expression profiles in non-small cell lung cancer

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Alterations of 3p21.31 tumor suppressor genes in head and neck squamous cell carcinoma: Correlation with progression and prognosis.

7 January 2021

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Two novel functions of hyaluronidase-2 (Hyal2) are formation of the glycocalyx and control of CD44-ERM interactions

7 January 2021

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Expression patterns of hyaluronan, hyaluronan synthases and hyaluronidases indicate a role for hyaluronan in the progression of endometrial cancer.

7 January 2021

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Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1

7 January 2021

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TGF-beta1 inhibits NF-kappaB activity through induction of IkappaB-alpha expression in human salivary gland cells: a possible mechanism of growth suppression by TGF-beta1.

7 January 2021

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5-Fluorouracil induces apoptosis through the suppression of NF-kappaB activity in human salivary gland cancer cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGENO.2015.10.002

10.1016/J.YGENO.2015.10.002

7 January 2021

Identifiers

DOI

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28 September 2017

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PubMed ID

26453961