Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras (Q41192006)

28 September 2017

Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras (English)

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28 September 2017

Monia BP

1

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28 September 2017

Johnston JF

series ordinal

2

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28 September 2017

Sasmor H

series ordinal

3

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28 September 2017

Cummins LL

series ordinal

4

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28 September 2017

language of work or name

English

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publication date

1 June 1996

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Journal of Biological Chemistry

28 September 2017

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28 September 2017

271

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28 September 2017

24

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28 September 2017

14533-14540

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Rate of degradation of [alpha]- and [beta]-oligodeoxynucleotides in Xenopus oocytes. Implications for anti-messenger strategies

28 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Partial protection of oncogene, anti-sense oligodeoxynucleotides against serum nuclease degradation using terminal methylphosphonate groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Modified deoxyoligonucleotides stable to exonuclease degradation in serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Nucleoside phosphorothioates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Physicochemical properties of phosphorothioate oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Kinetic characteristics of Escherichia coli RNase H1: cleavage of various antisense oligonucleotide-RNA duplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Stimulation of murine lymphocyte proliferation by a phosphorothioate oligonucleotide with antisense activity for herpes simplex virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

alpha-DNA II. Synthesis of unnatural alpha-anomeric oligodeoxyribonucleotides containing the four usual bases and study of their substrate activities for nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Highly efficient chemical synthesis of 2'-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

2'-O-alkyl oligoribonucleotides as antisense probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Nucleotide sequence analysis of the T24 human bladder carcinoma oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

alpha-Oligodeoxynucleotide stability in serum, subcellular extracts and culture media

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Sugar modified oligonucleotides. I. Carbo-oligodeoxynucleotides as potential antisense agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14533

21 January 2018

Identifiers

DOI

10.1074/JBC.271.24.14533

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28 September 2017

1 reference