Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism (Q41143647)

27 September 2017

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism (English)

1 reference

27 September 2017

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jean-Baptiste Demoulin

12

1 reference

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6 June 2020

Patrice D. Cani

18

1 reference

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6 June 2020

Hubert Plovier

2

1 reference

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6 June 2020

Matthias Van Hul

4

1 reference

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6 June 2020

Nathalie M. Delzenne

11

1 reference

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6 June 2020

Schalk van der Merwe

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Fredrik Bäckhed

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Daniel Monleon

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

8

Lucie Geurts

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1

Thibaut Duparc

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

5

Ahmed Essaghir

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

7

Sébastien Matamoros

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

10

Céline Druart

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

17

Amandine Everard

1 reference

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6 June 2020

author name string

Vannina G Marrachelli

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Mercedes M Pardo-Tendero

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jos van Pelt

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

language of work or name

English

0 references

publication date

5 May 2016

1 reference

27 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

66

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

620-632

1 reference

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6 June 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

Cytochrome P450 ω-Hydroxylases in Inflammation and Cancer

6 June 2020

cites work

1 reference

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Hepatic TLR4 signaling in obese NAFLD

27 September 2017

1 reference

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Metabolite profiling in plasma and tissues of ob/ob and db/db mice identifies novel markers of obesity and type 2 diabetes

27 September 2017

1 reference

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Association of Adipose Tissue Inflammation With Histologic Severity of Nonalcoholic Fatty Liver Disease.

27 September 2017

1 reference

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Novel protein glycan side-chain biomarker and risk of incident type 2 diabetes mellitus

27 September 2017

1 reference

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Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota.

27 September 2017

1 reference

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Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease.

27 September 2017

1 reference

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Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status

27 September 2017

1 reference

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STRING v10: protein-protein interaction networks, integrated over the tree of life

27 September 2017

1 reference

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The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease.

27 September 2017

1 reference

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Hepatocyte Toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance

27 September 2017

1 reference

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Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity

27 September 2017

1 reference

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The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Innate immune receptors: key regulators of metabolic disease progression

27 September 2017

1 reference

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Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity

27 September 2017

1 reference

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Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats

27 September 2017

1 reference

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Therapeutic modulation of microbiota-host metabolic interactions.

27 September 2017

1 reference

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Interplay between lipids and branched-chain amino acids in development of insulin resistance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?

27 September 2017

1 reference

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The cellular and signaling networks linking the immune system and metabolism in disease

27 September 2017

1 reference

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Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota

27 September 2017

1 reference

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Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complications

27 September 2017

1 reference

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The cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid system: a regulator of endothelial precursor cells derived from human umbilical cord blood

27 September 2017

1 reference

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Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

27 September 2017

1 reference

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Inflammatory mechanisms in obesity

27 September 2017

1 reference

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Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice

27 September 2017

1 reference

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Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data

27 September 2017

1 reference

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Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Macrophages, inflammation, and insulin resistance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Increased CYP2J3 expression reduces insulin resistance in fructose-treated rats and db/db mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

CD11c expression in adipose tissue and blood and its role in diet-induced obesity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Epoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model

27 September 2017

1 reference

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Metabolic endotoxemia initiates obesity and insulin resistance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Action of epoxyeicosatrienoic acids on cellular function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

14,15-Dihydroxyeicosatrienoic acid activates peroxisome proliferator-activated receptor-alpha

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Regulation of carbohydrate metabolism by the farnesoid X receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Muscle and liver insulin resistance indexes derived from the oral glucose tolerance test.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

A nonsense polymorphism (R392X) in TLR5 protects from obesity but predisposes to diabetes.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Obesity and type 2 diabetes impair insulin-induced suppression of glycogenolysis as well as gluconeogenesis.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Metabolite identification in human liver needle biopsies by high-resolution magic angle spinning 1H NMR spectroscopy

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5529962

Stearoyl-CoA Desaturase 1 (SCD1) is a key factor mediating diabetes in MyD88-deficient mice

4 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27196572

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Silencing of FGF-21 expression promotes hepatic gluconeogenesis and glycogenolysis by regulation of the STAT3-SOCS3 signal

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27196572

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1136/GUTJNL-2015-310904

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27196572%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference