Modulation of tumor cell gene expression and phenotype by the organ-specific metastatic environment (Q41121039)

27 September 2017

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title

Modulation of tumor cell gene expression and phenotype by the organ-specific metastatic environment (English)

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27 September 2017

R Radinsky

1

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27 September 2017

1 December 1995

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27 September 2017

16

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Cancer and Metastasis Reviews

inferred from page(s)

published in

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27 September 2017

14

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27 September 2017

323-338

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27 September 2017

4

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https://scigraph.springernature.com/pub.10.1007/bf00690601

27 September 2017

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Metastatic behavior of tumor cells isolated from primary and metastatic human colorectal carcinomas implanted into different sites in nude mice

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Does P-Glycoprotein Predict Response to Chemotherapy, and If So, Is There a Reliable Way to Detect It?

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Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5-fluorouracil.

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A rapid colorimetric in situ messenger RNA hybridization technique for analysis of epidermal growth factor receptor in paraffin-embedded surgical specimens of human colon carcinomas

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Genetic analysis of invasion and metastasis

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The involvement of oncogenes and tumor suppressor genes in the control of apoptosis

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Expression of hepatocyte growth factor gene in endothelial and Kupffer cells of damaged rat livers, as revealed by in situ hybridization

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p53 functions as a cell cycle control protein in osteosarcomas

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Apoptosis is associated with the extensive B cell death in the sheep ileal Peyer's patch and the chicken bursa of Fabricius: a possible role in B cell selection

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Metastasis associated MTS1 and NM23 genes affect tubulin polymerisation in B16 melanomas: a possible mechanism of their regulation of metastatic behaviour of tumours

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Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase

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Early multidrug resistance, defined by changes in intracellular doxorubicin distribution, independent of P-glycoprotein

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'Seed and soil' revisited: mechanisms of site-specific metastasis

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Correlation between molecular and clinical events in the evolution of chronic myelocytic leukemia to blast crisis

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Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells.

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Homologous and heterologous regulation of alpha-melanocyte-stimulating hormone receptors in human and mouse melanoma cell lines

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Intrinsic or acquired drug resistance and metastasis: are they linked phenotypes?

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Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

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Paracrine growth regulation of human colon carcinoma organ-specific metastasis

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Critical factors regulating site-specific brain metastasis of murine melanomas

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Regulation of tyrosinase in human melanocytes grown in culture

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Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes

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Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis

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Chromosomes 8, 12, and 17 copy number in Astler-Coller stage C colon cancer in relation to proliferative activity and DNA ploidy

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Selective killing of tumor cells using EGF or TGF alpha-Pseudomonas exotoxin chimeric molecules

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Mutations in the p53 gene occur in diverse human tumour types

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Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells

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12 December 2020

Effects of interferon on differentiation of normal and tumor cells

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Interferons modulate the expression of hormone receptors on the surface of murine melanoma cells

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Tyrosinase activity and abundance in Cloudman melanoma cells

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p53 is required for radiation-induced apoptosis in mouse thymocytes

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12 December 2020

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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12 December 2020

Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies

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12 December 2020

Characterization of a human osteosarcoma cell line (Saos-2) with osteoblastic properties

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12 December 2020

Site-dependent differences in response of the UV-2237 murine fibrosarcoma to systemic therapy with adriamycin

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12 December 2020

p53 function and dysfunction

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12 December 2020

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

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12 December 2020

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

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12 December 2020

The distribution of secondary growths in cancer of the breast. 1889

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Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53

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Melanotropin–daunomycin conjugate shows receptor-mediated cytotoxicity in cultured murine melanoma cells

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12 December 2020

Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells

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12 December 2020

Induction of differentiation by tumour necrosis factor in HL-60 cells is associated with the formation of large DNA fragments

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12 December 2020

B16-G4F mouse melanoma cells: an MSH receptor-deficient cell clone

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12 December 2020

Induction of monocytic differentiation and bone resorption by 1,25-dihydroxyvitamin D3.

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12 December 2020

Modulation of tumor cell response to chemotherapy by the organ environment

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12 December 2020

Increased mdr-1/P-glycoprotein expression after treatment of human colon carcinoma cells with P-glycoprotein antagonists.

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12 December 2020

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

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12 December 2020

Site-specific metastasis of mouse melanomas and a fibrosarcoma in the brain or meninges of syngeneic animals

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12 December 2020

Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts.

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12 December 2020

Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture

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12 December 2020

A death in the life of p53

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12 December 2020

Experimental nude mouse model of human colorectal cancer liver metastases

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12 December 2020

Mechanisms and clinical significance of multidrug resistance

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12 December 2020

Treatment of congenital osteopetrosis with high-dose calcitriol.

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12 December 2020

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

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12 December 2020

Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice.

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12 December 2020

Cytokines in human melanoma cells: synthesis, autocrine stimulation and regulatory functions--an overview.

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12 December 2020

Experimental metastasis correlates with cyclic AMP accumulation in B16 melanoma clones

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12 December 2020

Genetic control of cancer metastasis

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12 December 2020

Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas

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12 December 2020

Cellular growth response to epidermal growth factor in colon carcinoma cells with an amplified epidermal growth factor receptor derived from a familial adenomatous polyposis patient

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12 December 2020

Modulation of Doxorubicin sensitivity and level of p-glycoprotein expression in human colon-carcinoma cells by ectopic and orthotopic environments in nude-mice.

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12 December 2020

Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor alpha in the progression of prostatic neoplasms

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12 December 2020

The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia

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12 December 2020

Mutant p53 proteins bind DNA abnormally in vitro

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12 December 2020

Cancer progression and growth: relationship of paracrine and autocrine growth mechanisms to organ preference of metastasis

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12 December 2020

Investigation of the regulation of pigmentation in alpha-melanocyte-stimulating hormone responsive and unresponsive cultured B16 melanoma cells

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12 December 2020

Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1.

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12 December 2020

Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism

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12 December 2020

Growth stimulation by coexpression of transforming growth factor-alpha and epidermal growth factor-receptor in normal and adenomatous human colon epithelium

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12 December 2020

Mitogen-activated protein kinase stimulation by a tyrosine kinase-negative epidermal growth factor receptor

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12 December 2020

Adenocarcinoma of the proximal colon. Sites of initial dissemination and patterns of recurrence following surgery alone

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12 December 2020

Rearrangement of the p53 gene in human osteogenic sarcomas

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12 December 2020

α-MSH causes a small rise in cAMP but has no effect on basal or ultraviolet-stimulated melanogenesis in human melanocytes

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12 December 2020

Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies.

1 reference

12 December 2020

Transforming growth factor-alpha-Pseudomonas exotoxin fusion protein (TGF-alpha-PE38) treatment of subcutaneous and intracranial human glioma and medulloblastoma xenografts in athymic mice.

1 reference

12 December 2020

Expression of the receptor for epidermal growth factor correlates with increased dosage of chromosome 7 in malignant melanoma

1 reference

12 December 2020

Phenotype-associated changes in the effects of 1,25-dihydroxyvitamin D3 on alkaline phosphatase and bone GLA-protein of rat osteoblastic cells

1 reference

12 December 2020

Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA.

1 reference

12 December 2020

P-glycoproteins: mediators of multidrug resistance

1 reference

12 December 2020

p53 mutations in human cancers

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12 December 2020

Endocrine responsiveness in human melanocytes and melanoma cells in culture

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12 December 2020

Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form

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12 December 2020

Heterogeneity of cytokine and growth factor gene expression in human melanoma cells with different metastatic potentials.

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12 December 2020

Receptor protein-tyrosine kinases and their signal transduction pathways

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12 December 2020

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

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12 December 2020

Murine, not human, cell line

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12 December 2020

Immunochemical analysis of the modulation of human melanoma-associated antigens by DNA recombinant immune interferon

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12 December 2020

MSH receptor expression and the relationship to melanogenesis and metastatic activity in B16 melanoma

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12 December 2020

The epidermal growth factor receptor as a target for therapy with antireceptor monoclonal antibodies

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12 December 2020

Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities

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12 December 2020

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

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12 December 2020

Tumor resistance to alkylating agents conferred by mechanisms operative only in vivo.

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12 December 2020

Increased experimental metastatic capacity of a murine melanoma following induction of differentiation

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12 December 2020

Accelerated growth of human colon cancer cells in nude mice undergoing liver regeneration

1 reference

12 December 2020

Regulation of tyrosinase synthesis and its processing in the hair follicular melanocytes of the mouse during eumelanogenesis and phaeomelanogenesis

1 reference

12 December 2020

P-glycoprotein expression during tumor progression in the rat liver

1 reference

12 December 2020

Transforming growth factor receptors in liver regeneration following partial hepatectomy in the rat

1 reference

12 December 2020

Ultraviolet radiation directly induces pigment production by cultured human melanocytes

1 reference

12 December 2020

Transcriptional induction of the melanocyte-stimulating hormone receptor in brain metastases of murine K-1735 melanoma

1 reference

12 December 2020

Genetics of multidrug resistance

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12 December 2020

Multidrug resistance: P-glycoprotein and its allies--the elusive foes.

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12 December 2020

MDR1 RNA levels in human renal cell carcinomas: correlation with grade and prediction of reversal of doxorubicin resistance by quinidine in tumor explants

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12 December 2020

Multidrug resistance: molecular biology and clinical relevance.

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12 December 2020

Function and regulation of the human multidrug resistance gene

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12 December 2020

The receptor for EGF and its ligands - expression, prognostic value and target for therapy in cancer (review).

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12 December 2020

Clinical and pathological associations with allelic loss in colorectal carcinoma [corrected].

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12 December 2020

Intertumoral heterogeneity of receptor-tyrosine kinases expression in human melanoma cell lines with different metastatic capabilities

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12 December 2020

Expression of a multidrug resistance gene in human cancers

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12 December 2020

Specific short transmembrane sequences can inhibit transformation by the mutant neu growth factor receptor in vitro and in vivo.

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12 December 2020

Mechanisms of human tumor metastasis studied in patients with peritoneovenous shunts

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12 December 2020

Identifiers

DOI

10.1007/BF00690601

1 reference

PubMed ID

8821093

Dimensions Publication ID

27 September 2017

0 references

1 reference

PubMed ID

8821093