Inhibition of Inosine-5'-monophosphate Dehydrogenase from Bacillus anthracis: Mechanism Revealed by Pre-Steady-State Kinetics (Q41105047)

26 September 2017

Inhibition of Inosine-5'-monophosphate Dehydrogenase from Bacillus anthracis: Mechanism Revealed by Pre-Steady-State Kinetics (English)

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26 September 2017

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2

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12 June 2020

author name string

Yang Wei

1

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12 June 2020

Runhan Yu

3

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12 June 2020

Gyan Modi

4

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12 June 2020

Lizbeth Hedstrom

5

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12 June 2020

language of work or name

English

0 references

publication date

19 August 2016

1 reference

26 September 2017

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12 June 2020

volume

55

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12 June 2020

issue

37

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12 June 2020

page(s)

5279-5288

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A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity

12 June 2020

cites work

1 reference

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Repurposing cryptosporidium inosine 5'-monophosphate dehydrogenase inhibitors as potential antibacterial agents.

26 September 2017

1 reference

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Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis

26 September 2017

1 reference

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Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase

26 September 2017

1 reference

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Phthalazinone inhibitors of inosine-5'-monophosphate dehydrogenase from Cryptosporidium parvum.

26 September 2017

1 reference

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A pre-steady state kinetic analysis of the αY60W mutant of trans-3-chloroacrylic acid dehalogenase: implications for the mechanism of the wild-type enzyme

26 September 2017

1 reference

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Selective and potent urea inhibitors of cryptosporidium parvum inosine 5'-monophosphate dehydrogenase

26 September 2017

1 reference

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Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes

26 September 2017

1 reference

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Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH.

26 September 2017

1 reference

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Reaction of cis-3-chloroacrylic acid dehalogenase with an allene substrate, 2,3-butadienoate: hydration via an enamine

26 September 2017

1 reference

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Tackling antibiotic resistance

26 September 2017

1 reference

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Antimicrobials for bacterial bioterrorism agents

26 September 2017

1 reference

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The antibiotic potential of prokaryotic IMP dehydrogenase inhibitors

26 September 2017

1 reference

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Structural determinants of inhibitor selectivity in prokaryotic IMP dehydrogenases

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524190

The Structural Basis of Cryptosporidium-Specific IMP Dehydrogenase Inhibitor Selectivity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524190

Fitting enzyme kinetic data with KinTek Global Kinetic Explorer

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524190

Antibiotics for emerging pathogens

26 September 2017

1 reference

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Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase

26 September 2017

1 reference

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Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524190

IMP dehydrogenase: structure, mechanism, and inhibition

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524190

FitSpace explorer: an algorithm to evaluate multidimensional parameter space in fitting kinetic data

26 September 2017

1 reference

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Global kinetic explorer: a new computer program for dynamic simulation and fitting of kinetic data

26 September 2017

1 reference

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Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524190

Inactivation of inosine 5'-monophosphate dehydrogenase by the antiviral agent 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide 5'-monophosphate

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524190

Determining confidence intervals for parameters derived from analysis of equilibrium analytical ultracentrifugation data.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524190

Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

26 September 2017

1 reference

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Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli

26 September 2017

1 reference

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Insights into enzyme function from studies on mutants of dihydrofolate reductase

26 September 2017

1 reference

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Global analysis of biochemical and biophysical data

26 September 2017

1 reference

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IMP dehydrogenase, an enzyme linked with proliferation and malignancy

26 September 2017

1 reference

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A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases

26 September 2017

1 reference

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DynaFit--a software package for enzymology.

17 June 2018

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Parameter estimates from nonlinear models.

19 August 2018

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Symbolism and terminology in enzyme kinetics. Recommendations 1981

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27541177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The extinction coefficients of the reduced band of pyridine nucleotides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27541177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A tetrahedral intermediate in the EPSP synthase reaction observed by rapid quench kinetics

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27541177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ACS.BIOCHEM.6B00265

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12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27541177%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

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