Nerve growth factor induces transcription of the p21 WAF1/CIP1 and cyclin D1 genes in PC12 cells by activating the Sp1 transcription factor (Q41094353)

26 September 2017

Nerve growth factor induces transcription of the p21 WAF1/CIP1 and cyclin D1 genes in PC12 cells by activating the Sp1 transcription factor (English)

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26 September 2017

G Z Yan

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

15 May 2020

E B Ziff

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

15 May 2020

language of work or name

English

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publication date

1 August 1997

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26 September 2017

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

15 May 2020

volume

17

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

15 May 2020

issue

16

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

15 May 2020

page(s)

6122-6132

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

Overexpression of cyclin D1 and cyclin E in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.

15 May 2020

cites work

1 reference

12 December 2020

Nerve growth factor regulates the expression and activity of p33cdk2 and p34cdc2 kinases in PC12 pheochromocytoma cells.

1 reference

12 December 2020

Positive and negative regulation of D-type cyclin expression in skeletal myoblasts by basic fibroblast growth factor and transforming growth factor beta. A role for cyclin D1 in control of myoblast differentiation

1 reference

12 December 2020

Nerve growth factor has both mitogenic and antimitogenic activity

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12 December 2020

Evidence for communication between nerve growth factor and protein tyrosine phosphorylation

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12 December 2020

Neuron-specific expression of the synapsin II gene is directed by a specific core promoter and upstream regulatory elements.

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12 December 2020

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

12 December 2020

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

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12 December 2020

A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein

1 reference

12 December 2020

Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif

1 reference

12 December 2020

Inhibition of cell growth by transforming growth factor beta 1 is associated with p53-independent induction of p21 in gastric carcinoma cells.

1 reference

12 December 2020

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

1 reference

12 December 2020

Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation

1 reference

12 December 2020

Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts.

1 reference

12 December 2020

CDK6 (PLSTIRE) and CDK4 (PSK-J3) are a distinct subset of the cyclin-dependent kinases that associate with cyclin D1.

1 reference

12 December 2020

Identification of cells expressing a D type G1 cyclin in matured brain: implication for its role in neuronal function.

1 reference

12 December 2020

Nerve growth factor-induced accumulation of PC12 cells expressing cyclin D1: evidence for a G1 phase block

1 reference

12 December 2020

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

12 December 2020

A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation

1 reference

12 December 2020

Cloning of the rat gene encoding choline acetyltransferase, a cholinergic neuron-specific marker

1 reference

12 December 2020

Inhibition of cyclin-dependent kinases by p21

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12 December 2020

Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle

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12 December 2020

Constitutive overexpression of CDK2 inhibits neuronal differentiation of rat pheochromocytoma PC12 cells

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12 December 2020

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

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12 December 2020

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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12 December 2020

Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases

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12 December 2020

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

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12 December 2020

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1 reference

12 December 2020

Induction of Sp1 phosphorylation and NF-kappa B-independent HIV promoter domain activity in T lymphocytes stimulated by okadaic acid

1 reference

12 December 2020

Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway

1 reference

12 December 2020

Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor

1 reference

12 December 2020

Sequencing of the rat light neurofilament promoter reveals differences in methylation between expressing and non-expressing cell lines, but not tissues

1 reference

12 December 2020

Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins

1 reference

12 December 2020

Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

1 reference

12 December 2020

A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids.

1 reference

12 December 2020

Immediate upstream promoter regions required for neurospecific expression of SNAP-25.

1 reference

12 December 2020

Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators

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12 December 2020

The CDK inhibitor p21WAF1/Cip1 is induced through a p300-dependent mechanism during NGF-mediated neuronal differentiation of PC12 cells

1 reference

12 December 2020

Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression.

1 reference

12 December 2020

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12 December 2020

NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1

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12 December 2020

Adenovirus 5 E1A proteins disrupt the neuronal phenotype and growth factor responsiveness of PC12 cells by a conserved region 1-dependent mechanism

1 reference

12 December 2020

Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1

1 reference

12 December 2020

Cyclins, cyclin-dependent kinases and differentiation

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12 December 2020

Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

1 reference

12 December 2020

Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3

1 reference

12 December 2020

p21-containing cyclin kinases exist in both active and inactive states

1 reference

12 December 2020

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

1 reference

12 December 2020

The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells

1 reference

12 December 2020

Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids

1 reference

12 December 2020

Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site

1 reference

12 December 2020

Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

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12 December 2020

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1 reference

12 December 2020

Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation

1 reference

12 December 2020

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

1 reference

12 December 2020

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

1 reference

12 December 2020

Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

1 reference

12 December 2020

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

1 reference

12 December 2020

Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-Fos

1 reference

12 December 2020

A method for isolation of intact, translationally active ribonucleic acid.

1 reference

12 December 2020

Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators

1 reference

12 December 2020

Expression of the positive regulator of cell cycle progression, cyclin D3, is induced during differentiation of myoblasts into quiescent myotubes.

1 reference

12 December 2020

Nerve growth factor-induced differentiation of PC12 cells: evaluation of changes in RNA and DNA metabolism

1 reference

12 December 2020

Silencer elements modulate the expression of the gene for the neuron-glia cell adhesion molecule, Ng-CAM.

1 reference

12 December 2020

AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

1 reference

12 December 2020

The retinoblastoma protein as a fundamental mediator of growth and differentiation signals

1 reference

12 December 2020

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

1 reference

12 December 2020

Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression

1 reference

12 December 2020

Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression

1 reference

12 December 2020

Amplification and expression of the human cyclin D gene in esophageal cancer

1 reference

12 December 2020

Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells

1 reference

12 December 2020

p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells

1 reference

12 December 2020

The retinoblastoma gene product regulates Sp1-mediated transcription

1 reference

12 December 2020

WAF1, a potential mediator of p53 tumor suppression

1 reference

12 December 2020

Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage

1 reference

12 December 2020

Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

1 reference

12 December 2020

The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells

1 reference

12 December 2020

Reduced cyclin D1 expression in the cerebella of nutritionally deprived rats correlates with developmental delay and decreased cellular DNA synthesis.

1 reference

12 December 2020

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

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12 December 2020

Nerve growth factor-treated, neurite-bearing PC12 cells continue to synthesize DNA

1 reference

12 December 2020

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1 reference

12 December 2020

The role of estrogens on the proliferation of human breast tumor cells (MCF-7).

1 reference

12 December 2020

Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes

1 reference

12 December 2020

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

1 reference

12 December 2020

The DNA sequence encompassing the transcription start site of a TATA-less promoter contains enough information to drive neuron-specific transcription

1 reference

12 December 2020

Novel DNA binding proteins participate in the regulation of human neurofilament H gene expression

1 reference

12 December 2020

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

1 reference

12 December 2020

Effect of nerve growth factor on the expression of cell cycle regulatory proteins in PC12 cells: dissection of the neurotrophic response from the anti-mitogenic response

1 reference

12 December 2020

Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identity with the mitogen-activated MAP kinase of fibroblastic cells

1 reference

12 December 2020

MN20, a D2 cyclin, is transiently expressed in selected neural populations during embryogenesis.

1 reference

12 December 2020

Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription

1 reference

12 December 2020

Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53.

1 reference

12 December 2020

Induction of p21 (WAF-1/CIP1) during differentiation

1 reference

12 December 2020

Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells

1 reference

12 December 2020

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

1 reference

12 December 2020

Unscheduled expression of cyclins D1 and D3 in human tumour cell lines

1 reference

12 December 2020

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1 reference

12 December 2020

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

1 reference

12 December 2020

A (G+C)-rich motif in the aldolase C promoter functions as a constitutive transcriptional enhancer element.

1 reference

12 December 2020

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

1 reference

12 December 2020

10.1523/JNEUROSCI.17-16-06122.1997

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

15 May 2020

1 reference