p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration (Q41093716)

26 September 2017

p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration (English)

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26 September 2017

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Mark R Frey

1

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26 September 2017

Rebecca S Dise

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2

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26 September 2017

Karen L Edelblum

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3

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26 September 2017

D Brent Polk

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4

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26 September 2017

language of work or name

English

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publication date

30 November 2006

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26 September 2017

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26 September 2017

25

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26 September 2017

24

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26 September 2017

5683-5692

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describes a project that uses

26 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1698902/fullTextXML

inferred from PubMed Central ID database lookup

cites work

p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy

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Activation of p38 mitogen-activated protein kinase promotes epidermal growth factor receptor internalization

26 September 2017

1 reference

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Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

26 September 2017

1 reference

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Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis

26 September 2017

1 reference

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Epidermal growth factor-stimulated intestinal epithelial cell migration requires Src family kinase-dependent p38 MAPK signaling

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease

26 September 2017

1 reference

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c-Cbl-mediated ubiquitinylation is required for epidermal growth factor receptor exit from the early endosomes

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits

26 September 2017

1 reference

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The epidermal growth factor receptor pathway and its inhibition as anticancer therapy.

26 September 2017

1 reference

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Stimulation of cell proliferation by endosomal epidermal growth factor receptor as revealed through two distinct phases of signaling

26 September 2017

1 reference

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p38 and ERK1/2 coordinate cellular migration and proliferation in epithelial wound healing: evidence of cross-talk activation between MAP kinase cascades

26 September 2017

1 reference

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Negative receptor signalling

26 September 2017

1 reference

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26 September 2017

1 reference

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Dichotomal role of inhibition of p38 MAPK with SB 203580 in experimental colitis

26 September 2017

1 reference

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Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes.

26 September 2017

1 reference

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RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation

26 September 2017

1 reference

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The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components

26 September 2017

1 reference

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The ErbB signaling network: receptor heterodimerization in development and cancer

26 September 2017

1 reference

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Rab7: a key to lysosome biogenesis

26 September 2017

1 reference

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Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

26 September 2017

1 reference

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c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Epidermal growth factor receptor-stimulated intestinal epithelial cell migration requires phospholipase C activity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities

26 September 2017

1 reference

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Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice

26 September 2017

1 reference

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Active EGF receptors have limited access to PtdIns(4,5)P(2) in endosomes: implications for phospholipase C and PI 3-kinase signaling.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Large-scale screening assay to measure epidermal growth factor internalization

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

p38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Nitric oxide-induced epidermal growth factor-dependent phosphorylations in A431 tumour cells.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Uncoupling the p38 MAPK kinase in IBD: a double edged sword?

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Protective effect of epidermal growth factor in an experimental model of colitis in rats.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Stimulation and inhibition of proliferation in the small intestinal crypts of the mouse after in vivo administration of growth factors

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

19 August 2018

Caveolae Meet Endosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698902

Kinetic mechanism of the p38-alpha MAP kinase: phosphoryl transfer to synthetic peptides

2 December 2018

1 reference

12 December 2020

p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease

1 reference

12 December 2020

Deletion of the gene encoding c-Cbl alters the ability of osteoclasts to migrate, delaying resorption and ossification of cartilage during the development of long bones

1 reference

12 December 2020

Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

1 reference

12 December 2020

Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells

1 reference

12 December 2020

Role of threonine residues in regulation of the epidermal growth factor receptor by protein kinase C and mitogen-activated protein kinase

1 reference

12 December 2020

NDF/heregulin-induced cell cycle changes and apoptosis in breast tumour cells: role of PI3 kinase and p38 MAP kinase pathways

1 reference

12 December 2020

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7601457

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26 September 2017

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26 September 2017

1 reference