Fas induces cytoplasmic apoptotic responses and activation of the MKK7-JNK/SAPK and MKK6-p38 pathways independent of CPP32-like proteases. (Q41075660)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9362518%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Fas induces cytoplasmic apoptotic responses and activation of the MKK7-JNK/SAPK and MKK6-p38 pathways independent of CPP32-like proteases (English)

1 reference

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7 November 2019

0 references

2

1 reference

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7 November 2019

author name string

F Toyoshima

series ordinal

1

1 reference

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7 November 2019

E Nishida

series ordinal

3

1 reference

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7 November 2019

language of work or name

English

0 references

publication date

1 November 1997

1 reference

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7 November 2019

number of pages

11

1 reference

inferred from page(s)

published in

Journal of Cell Biology

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7 November 2019

volume

139

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7 November 2019

page(s)

1005-1015

1 reference

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7 November 2019

issue

4

1 reference

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Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis

7 November 2019

cites work

1 reference

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Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases

26 September 2017

1 reference

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The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32

26 September 2017

1 reference

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Purification and identification of a major activator for p38 from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2

26 September 2017

1 reference

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Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells

26 September 2017

1 reference

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In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

26 September 2017

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

26 September 2017

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Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

26 September 2017

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ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B

26 September 2017

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A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

26 September 2017

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Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade

26 September 2017

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

26 September 2017

1 reference

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Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

26 September 2017

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ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis

26 September 2017

1 reference

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Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32

26 September 2017

1 reference

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Mch3, a novel human apoptotic cysteine protease highly related to CPP32.

26 September 2017

1 reference

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The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

26 September 2017

1 reference

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The stress-activated protein kinase subfamily of c-Jun kinases

26 September 2017

1 reference

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

26 September 2017

1 reference

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Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

26 September 2017

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

26 September 2017

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CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme

26 September 2017

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Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

26 September 2017

1 reference

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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

26 September 2017

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

26 September 2017

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C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

26 September 2017

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

26 September 2017

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Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases

26 September 2017

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Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases

26 September 2017

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Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family

26 September 2017

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Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

26 September 2017

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Evidence for multiple activators for stress-activated protein kinase/c-Jun amino-terminal kinases. Existence of novel activators

26 September 2017

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A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells

26 September 2017

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

26 September 2017

1 reference

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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

26 September 2017

1 reference

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A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

26 September 2017

1 reference

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

26 September 2017

1 reference

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

26 September 2017

1 reference

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A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor

26 September 2017

1 reference

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Mechanisms and Functions of Cell Death

26 September 2017

1 reference

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The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

26 September 2017

1 reference

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Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

26 September 2017

1 reference

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The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death

26 September 2017

1 reference

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Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

26 September 2017

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JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells

26 September 2017

1 reference

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FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

26 September 2017

1 reference

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Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

26 September 2017

1 reference

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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

26 September 2017

1 reference

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Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

26 September 2017

1 reference

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Involvement of an ICE-like protease in Fas-mediated apoptosis

26 September 2017

1 reference

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A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses

26 September 2017

1 reference

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Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity

14 June 2018

1 reference

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A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

14 June 2018

1 reference

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Purification of an interleukin-1 beta converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains

14 June 2018

1 reference

12 December 2020

Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis

1 reference

12 December 2020

CPP32/apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis

1 reference

12 December 2020

Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells

1 reference

12 December 2020

A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells

1 reference

12 December 2020

Specific cleavage of alpha-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease

1 reference

12 December 2020

The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

1 reference

12 December 2020

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.139.4.1005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9362518%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9362518%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9362518%20AND%20SRC:MED&resulttype=core&format=json