Epstein-Barr virus nuclear antigen 2 is a transcriptional suppressor of the immunoglobulin mu gene: implications for the expression of the translocated c-myc gene in Burkitt's lymphoma cells. (Q41063703)

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English	Epstein-Barr virus nuclear antigen 2 is a transcriptional suppressor of the immunoglobulin mu gene: implications for the expression of the translocated c-myc gene in Burkitt's lymphoma cells.	scientific article

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15 October 2019

Epstein-Barr virus nuclear antigen 2 is a transcriptional suppressor of the immunoglobulin mu gene: implications for the expression of the translocated c-myc gene in Burkitt's lymphoma cells (English)

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15 October 2019

Burkitt lymphoma

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Epstein–Barr virus

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Michael Pawlita

4

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author name string

Jochner N

1

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15 October 2019

Eick D

2

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15 October 2019

Zimber-Strobl U

3

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Bornkamm GW

5

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Kempkes B

6

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1 January 1996

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15 October 2019

The EMBO Journal

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15 October 2019

15

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15 October 2019

375-382

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2

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15 October 2019

The Epstein-Barr virus immortalizing protein EBNA-2 is targeted to DNA by a cellular enhancer-binding protein

1 reference

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26 September 2017

Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation

1 reference

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26 September 2017

The Epstein-Barr virus nuclear antigen 2 interacts with an EBNA2 responsive cis-element of the terminal protein 1 gene promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

Epstein-Barr virus: adaptation to a life within the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

Epstein-Barr virus strategy in normal and neoplastic B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

The human J kappa recombination signal sequence binding protein (RBP-J kappa) targets the Epstein-Barr virus EBNA2 protein to its DNA responsive elements.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

The Spi-1/PU.1 and Spi-B ets family transcription factors and the recombination signal binding protein RBP-J kappa interact with an Epstein-Barr virus nuclear antigen 2 responsive cis-element.

1 reference

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26 September 2017

Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1.

1 reference

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26 September 2017

Differential Epstein-Barr virus gene expression in B-cell subsets recovered from lymphomas in SCID mice after transplantation of human peripheral blood lymphocytes.

1 reference

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26 September 2017

Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

Crucial sequences within the Epstein-Barr virus TP1 promoter for EBNA2-mediated transactivation and interaction of EBNA2 with its responsive element

1 reference

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26 September 2017

Identification and characterization of an Epstein-Barr virus nuclear antigen 2-responsive cis element in the bidirectional promoter region of latent membrane protein and terminal protein 2 genes.

1 reference

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26 September 2017

Epstein-Barr virus nuclear antigen 3C is a transcriptional regulator

1 reference

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26 September 2017

Epstein-Barr virus nuclear protein 3C modulates transcription through interaction with the sequence-specific DNA-binding protein J kappa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments

1 reference

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26 September 2017

Extreme instability of myc mRNA in normal and transformed human cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

Deletion of the nontransforming Epstein-Barr virus strain P3HR-1 causes fusion of the large internal repeat to the DSL region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

Immunofluorescence and Herpes-Type Virus Particles in the P3HR-1 Burkitt Lymphoma Cell Line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas

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26 September 2017

The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma

1 reference

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26 September 2017

Immunoglobulin mRNA stability varies during B lymphocyte differentiation

1 reference

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26 September 2017

Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

Restricted expression of EBV latent genes and T-lymphocyte-detected membrane antigen in Burkitt's lymphoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor

1 reference

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26 September 2017

Epstein-Barr virus (EBV) induces expression of B-cell activation markers on in vitro infection of EBV-negative B-lymphoma cells

1 reference

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26 September 2017

Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation

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26 September 2017

A protein binding to the J kappa recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif

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26 September 2017

Expression of normal and translocated c-myc alleles in Burkitt's lymphoma cells: evidence for different regulation

1 reference

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26 September 2017

Epstein-Barr virus-encoded nuclear antigen 2 activates the viral latent membrane protein promoter by modulating the activity of a negative regulatory element

1 reference

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26 September 2017

The level of c-fgr RNA is increased by EBNA-2, an Epstein-Barr virus gene required for B-cell immortalization

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=449952

26 September 2017

cis-acting regulatory elements near the Epstein-Barr virus latent-infection membrane protein transcriptional start site

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26 September 2017

Stable transfection of Epstein-Barr virus (EBV) nuclear antigen 2 in lymphoma cells containing the EBV P3HR1 genome induces expression of B-cell activation molecules CD21 and CD23.

1 reference

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26 September 2017

Control of c-myc regulation in normal and neoplastic cells.

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26 September 2017

Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection

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26 September 2017

EBNA-2 transactivates a lymphoid-specific enhancer in the BamHI C promoter of Epstein-Barr virus

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26 September 2017

Epstein-Barr virus nuclear antigen 2 activates transcription of the terminal protein gene

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26 September 2017

myc function and regulation

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26 September 2017

Identification of critical cis elements involved in mediating Epstein-Barr virus nuclear antigen 2-dependent activity of an enhancer located upstream of the viral BamHI C promoter

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26 September 2017

The Epstein-Barr virus determined nuclear antigens EBNA-3A, -3B, and -3C repress EBNA-2-mediated transactivation of the viral terminal protein 1 gene promoter

1 reference

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26 September 2017

Epstein-Barr virus (EBV) nuclear-antigen-2-induced up-regulation of CD21 and CD23 molecules is dependent on a permissive cellular context

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14 June 2018

Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.

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14 June 2018

Pharmacologic activation of expression of immunodominant viral antigens: a new strategy for the treatment of Epstein-Barr-virus-associated malignancies

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14 June 2018

Immunoglobulin secretion by cell lines derived from African and American undifferentiated lymphomas of Burkitt's and non-Burkitt's type.

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14 June 2018

EBV-transformed lymphoblastoid cell lines down-regulate EBNA in parallel with secretory differentiation

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14 June 2018

Identification of the 37-kDa protein displaying a variable interaction with the erythroid cell membrane as glyceraldehyde-3-phosphate dehydrogenase

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14 June 2018

Geographical prevalence of two types of Epstein-Barr virus

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14 June 2018

Expression of Epstein-Barr virus-encoded proteins in nasopharyngeal carcinoma.

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14 June 2018

Epstein-Barr virus gene expression in nasopharyngeal carcinoma

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14 June 2018

Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes

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14 June 2018

Expression of Epstein-Barr virus latent gene products and related cellular activation and adhesion molecules in Hodgkin's disease and non-Hodgkin's lymphomas arising in patients without overt pre-existing immunodeficiency

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19 August 2018

Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa

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19 August 2018

Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

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12 December 2020

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10.1002/J.1460-2075.1996.TB00367.X

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15 October 2019

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Europe PubMed Central

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15 October 2019

1 reference

Europe PubMed Central

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15 October 2019

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