Quinone toxicity in DT-diaphorase-efficient and -deficient colon carcinoma cell lines (Q40977859)

25 September 2017

Quinone toxicity in DT-diaphorase-efficient and -deficient colon carcinoma cell lines (English)

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25 September 2017

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Karczewski JM

1

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25 September 2017

Peters JG

series ordinal

2

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25 September 2017

Noordhoek J

series ordinal

3

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25 September 2017

language of work or name

English

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publication date

1 January 1999

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25 September 2017

Biochemical Pharmacology

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25 September 2017

57

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25 September 2017

1

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25 September 2017

27-37

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Contribution of glutathione and glutathione-dependent enzymes in the reversal of adriamycin resistance in colon carcinoma cell lines

25 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Detoxification ability and toxicity of quinones in mouse and human tumor cell lines used for anticancer drug screening

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the National Cancer Institute Anticancer Drug Screen

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Molecular mechanisms of quinone cytotoxicity

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Mechanisms of toxicity of naphthoquinones to isolated hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Cytotoxicity of menadione and related quinones in freshly isolated rat hepatocytes: effects on thiol homeostasis and energy charge

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Redox cycling and sulphydryl arylation; their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

DT-diaphorase as a quinone reductase: a cellular control device against semiquinone and superoxide radical formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Inhibition of biliary taurocholate excretion during menadione metabolism in perfused rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Alterations of surface morphology caused by the metabolism of menadione in mammalian cells are associated with the oxidation of critical sulfhydryl groups in cytoskeletal proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Menadione-induced bleb formation in hepatocytes is associated with the oxidation of thiol groups in actin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Inhibition of hepatocyte plasma membrane Ca2+-ATPase activity by menadione metabolism and its restoration by thiols

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

DNA breakage caused by hydrogen peroxide produced during the metabolism of 2-methyl-1,4-naphthoquinone (menadione) does not contribute to the cytotoxic action of the quinone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Menadione-induced DNA fragmentation without 8-oxo-2′-deoxyguanosine formation in isolated rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Induction of dna damage by menadione (2-methyl-1,4-naphthoquinone) in primary cultures of rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

DNA damage and lethal effects of hydrogen peroxide and menadione in Chinese hamster cells: distinct mechanisms are involved

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Quinone-induced DNA single strand breaks in rat hepatocytes and human chronic myelogenous leukaemic K562 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Interaction with cellular ATP generating pathways mediates menadione-induced cytotoxicity in isolated rat hepatocytes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Toxicity determined in vitro by morphological alterations and neutral red absorption

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

The reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells: free radical formation and NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase) activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Methodologies for the application of monobromobimane to the simultaneous analysis of soluble and protein thiol components of biological systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

7 January 2021

Tissue sulfhydryl groups

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Role of thiol homeostasis and adenine nucleotide metabolism in the protective effects of fructose in quinone-induced cytotoxicity in rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

The role of lipid peroxidation in menadione-mediated toxicity in cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Exogenous glutathione protects intestinal epithelial cells from oxidative injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Reactivity of thiols towards derivatives of 2- and 6-methyl-1,4-naphthoquinone bioreductive alkylating agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

DT-diaphorase-catalysed reduction of 1,4-naphthoquinone derivatives and glutathionyl-quinone conjugates. Effect of substituents on autoxidation rates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Cytotoxicity of polycyclic aromatic hydrocarbon o-quinones in rat and human hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Effect of superoxide dismutase on the autoxidation of substituted hydro- and semi-naphthoquinones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Effect of glutathione on the redox transitions of naphthohydroquinone derivatives formed during DT-diaphorase catalysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Antioxidant and prooxidant functions of DT-diaphorase in quinone metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Antioxidant enzymes in the differentiated Caco-2 cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Time-dependent activity and expression of glutathione S-transferases in the human colon adenocarcinoma cell line Caco-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Glutathione S-transferase isoenzymes in human tumours and tumour derived cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Increased levels of glutathione S-transferase π transcript as a mechanism of resistance to ethacrynic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Biochemical characterization of a mitomycin C resistant colon cancer cell line variant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Formation and reduction of glutathione-protein mixed disulfides during oxidative stress. A study with isolated hepatocytes and menadione (2-methyl-1,4-naphthoquinone)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Protein S-thiolation in hepatocytes stimulated by t-butyl hydroperoxide, menadione, and neutrophils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

A comparison of proteins S-thiolated by glutathione to those arylated by acetaminophen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Inhibition of taurocholate efflux from rat hepatic canalicular membrane vesicles by glutathione disulfide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Interaction of a glutathione S-conjugate with glutathione reductase. Kinetic and X-ray crystallographic studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Quantitative succinic dehydrogenases histochemistry. A comparison of different tetrazolium salts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Reduction of a tetrazolium salt and superoxide generation in human tumor cells (HeLa).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

The possible role of vitamin K in the respiratory chain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Regulation of the pentose phosphate cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Stabilization of partially-purified glucose 6-phosphatase by fluoride. Is enzyme inactivation caused by dephosphorylation?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

Caco-2 cell metabolism of oxygen-derived radicals.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900288-3

10.1016/S0006-2952(98)00288-3

7 January 2021

Identifiers

DOI

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25 September 2017

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