Aging and cancer: are telomeres and telomerase the connection? (Q40966228)

25 September 2017

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title

Aging and cancer: are telomeres and telomerase the connection? (English)

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25 September 2017

Shay JW

1

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25 September 2017

1 November 1995

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Trends in Molecular Medicine

25 September 2017

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25 September 2017

1

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25 September 2017

8

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25 September 2017

378-384

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Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts

25 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

A role for both RB and p53 in the regulation of human cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Telomeric repeat from T. thermophila cross hybridizes with human telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Telomeres shorten during ageing of human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Telomeres, telomerase and senescence

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Telomere loss: mitotic clock or genetic time bomb?

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

A mutant with a defect in telomere elongation leads to senescence in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

TLC1: template RNA component of Saccharomyces cerevisiae telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Replicative senescence: the human fibroblast comes of age.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Telomere positional effects and the regulation of cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism?

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Specific association of human telomerase activity with immortal cells and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Correlating telomerase activity levels with human neuroblastoma outcomes

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Telomerase activity in small-cell and non-small-cell lung cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

The RNA component of human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

Functional characterization and developmental regulation of mouse telomerase RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2895%2993872-9

7 January 2021

10.1016/S1357-4310(95)93872-9

Identifiers

DOI

1 reference

25 September 2017

1 reference

PubMed ID

9415184