Gene targeting--homing in on alpha 2-adrenoceptor-subtype function (Q40892446)

24 September 2017

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title

Gene targeting--homing in on alpha 2-adrenoceptor-subtype function (English)

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24 September 2017

2

Kobilka BK

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24 September 2017

MacDonald E

1

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PubMed ID

9227000

24 September 2017

Scheinin M

series ordinal

3

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24 September 2017

1 June 1997

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Trends in Pharmacological Sciences

24 September 2017

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24 September 2017

18

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24 September 2017

211-219

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24 September 2017

6

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Molecular characterization of alpha 1- and alpha 2-adrenoceptors

24 September 2017

1 reference

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Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor

1 reference

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7 January 2021

Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype

1 reference

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7 January 2021

Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2

1 reference

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7 January 2021

Alpha 2-adrenoceptors: more subtypes but fewer functional differences.

1 reference

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7 January 2021

Heterologous expression of the cloned guinea pig alpha 2A, alpha 2B, and alpha 2C adrenoceptor subtypes. Radioligand binding and functional coupling to a CAMP-responsive reporter gene

1 reference

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7 January 2021

Molecular determinants of the alpha-2D adrenergic receptor subtype

1 reference

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7 January 2021

Cloning and expression of a fish alpha 2-adrenoceptor

1 reference

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7 January 2021

Use of recombinant human alpha 2-adrenoceptors to characterize subtype selectively of antagonist binding

1 reference

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7 January 2021

Coupling of human alpha 2-adrenoceptor subtypes to regulation of cAMP production in transfected S115 cells

1 reference

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7 January 2021

Alpha 2-adrenoceptors and I2 sites in the mammalian central nervous system

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7 January 2021

Medetomidine stereoisomers delineate two closely related subtypes of idazoxan (imidazoline) I-receptors in the guinea pig

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7 January 2021

Subclassification of presynaptic alpha 2-adrenoceptors: alpha 2D-autoreceptors and alpha 2D-adrenoceptors modulating release of acetylcholine in guinea-pig ileum

1 reference

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7 January 2021

Subtype classification of presynaptic alpha 2-adrenoceptors

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7 January 2021

The distribution and significance of CNS adrenoceptors examined with in situ hybridization

1 reference

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7 January 2021

Differential localization of alpha 2-adrenergic receptor subtypes in brain

1 reference

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7 January 2021

Expression of multiple alpha adrenergic receptor subtype messenger RNAs in the adult rat brain

1 reference

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7 January 2021

Distributions of mRNAs for alpha-2 adrenergic receptor subtypes in rat brain: an in situ hybridization study.

1 reference

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7 January 2021

Distribution of alpha 2-adrenergic receptor subtype gene expression in rat brain

1 reference

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7 January 2021

Expression of alpha 2 adrenoceptors during rat brain development--I. Alpha 2A messenger RNA expression.

1 reference

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7 January 2021

Expression of alpha 2 adrenoceptors during rat brain development--II. Alpha 2C messenger RNA expression and [3H]rauwolscine binding

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7 January 2021

Expression of alpha 2-adrenergic receptor subtypes in the mouse brain: evaluation of spatial and temporal information imparted by 3 kb of 5' regulatory sequence for the alpha 2A AR-receptor gene in transgenic animals.

1 reference

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7 January 2021

Immunohistochemical localization of alpha 2A-adrenergic receptors in catecholaminergic and other brainstem neurons in the rat.

1 reference

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7 January 2021

Perikaryal and synaptic localization of alpha 2A-adrenergic receptor-like immunoreactivity.

1 reference

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7 January 2021

Alpha 2A-adrenergic receptors are present in lower brainstem catecholaminergic and serotonergic neurons innervating spinal cord

1 reference

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7 January 2021

Distribution of alpha 2A-adrenergic receptor-like immunoreactivity in the rat central nervous system

1 reference

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7 January 2021

The three alpha 2-adrenergic receptor subtypes achieve basolateral localization in Madin-Darby canine kidney II cells via different targeting mechanisms

1 reference

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7 January 2021

Cardiovascular regulation in mice lacking alpha2-adrenergic receptor subtypes b and c.

1 reference

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7 January 2021

Central hypotensive effects of the alpha2a-adrenergic receptor subtype.

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7 January 2021

A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents

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7 January 2021

Adrenergic and imidazoline receptor-mediated responses to UK-14,304-18 (brimonidine) in rabbits and monkeys. A species difference

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Brimonidine in the prevention of intraocular pressure elevation following argon laser trabeculoplasty

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Cold-induced potentiation of alpha 2-adrenergic vasoconstriction in primary Raynaud's disease

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7 January 2021

Putting the 'A' in atypical: does α2-adrenoceptor antagonism account for the therapeutic advantage of new antipsychotics?

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7 January 2021

Altering the genome by homologous recombination

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7 January 2021

The new mouse genetics: altering the genome by gene targeting

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Transcriptional regulation. Converting an activator into a repressor

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Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

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Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice

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Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects

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7 January 2021

Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor

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Inverse agonism: pharmacological curiosity or potential therapeutic strategy?

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7 January 2021

Genetic alteration of alpha 2C-adrenoceptor expression in mice: influence on locomotor, hypothermic, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha 2-adrenoceptor agonist.

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7 January 2021

In vivo studies with antisense oligonucleotides

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7 January 2021

Mapping of opioid receptors using antisense oligodeoxynucleotides: correlating their molecular biology and pharmacology

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Antisense knockouts: molecular scalpels for the dissection of signal transduction

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7 January 2021

10.1016/S0165-6147(97)01063-8

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

9227000