The Fifth Transmembrane Segment of Cystic Fibrosis Transmembrane Conductance Regulator Contributes to Its Anion Permeation Pathway (Q40890193)

24 September 2017

The Fifth Transmembrane Segment of Cystic Fibrosis Transmembrane Conductance Regulator Contributes to Its Anion Permeation Pathway (English)

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24 September 2017

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transmembrane protein

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author name string

Jingyao Zhang

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6510985&resulttype=core&format=json

14 May 2020

Tzyh-Chang Hwang

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6510985&resulttype=core&format=json

14 May 2020

language of work or name

English

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publication date

10 June 2015

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24 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6510985&resulttype=core&format=json

14 May 2020

volume

54

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6510985&resulttype=core&format=json

14 May 2020

issue

24

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6510985&resulttype=core&format=json

14 May 2020

page(s)

3839-3850

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6510985&resulttype=core&format=json

Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy

14 May 2020

cites work

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12 December 2020

Arg352 is a major determinant of charge selectivity in the cystic fibrosis transmembrane conductance regulator chloride channel

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12 December 2020

Permeation through the CFTR chloride channel

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12 December 2020

Point mutations in the pore region directly or indirectly affect glibenclamide block of the CFTR chloride channel

1 reference

12 December 2020

Probing an open CFTR pore with organic anion blockers

1 reference

12 December 2020

Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)

1 reference

12 December 2020

Direct comparison of the functional roles played by different transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore

1 reference

12 December 2020

Location of a common inhibitor binding site in the cytoplasmic vestibule of the cystic fibrosis transmembrane conductance regulator chloride channel pore.

1 reference

12 December 2020

Time-dependent interactions of glibenclamide with CFTR: kinetically complex block of macroscopic currents

1 reference

12 December 2020

Oxidation and reduction control of the inactivation gating of Torpedo ClC-0 chloride channels

1 reference

12 December 2020

Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates

1 reference

12 December 2020

Variable reactivity of an engineered cysteine at position 338 in cystic fibrosis transmembrane conductance regulator reflects different chemical states of the thiol

1 reference

12 December 2020

The ABC protein turned chloride channel whose failure causes cystic fibrosis

1 reference

12 December 2020

CFTR: Ligand exchange between a permeant anion ([Au(CN)2]-) and an engineered cysteine (T338C) blocks the pore

1 reference

12 December 2020

Structure of a bacterial multidrug ABC transporter

1 reference

12 December 2020

Positive charges at the intracellular mouth of the pore regulate anion conduction in the CFTR chloride channel

1 reference

12 December 2020

Identification of a second blocker binding site at the cytoplasmic mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore.

1 reference

12 December 2020

Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP

1 reference

12 December 2020

Molecular mechanism of arachidonic acid inhibition of the CFTR chloride channel

1 reference

12 December 2020

CFTR inhibition by glibenclamide requires a positive charge in cytoplasmic loop three

1 reference

12 December 2020

Direct and indirect effects of mutations at the outer mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore.

1 reference

12 December 2020

Structure and mechanism of ABC transporter proteins.

1 reference

12 December 2020

Flexibility in the ABC transporter MsbA: Alternating access with a twist

1 reference

12 December 2020

CLC-0 and CFTR: chloride channels evolved from transporters

1 reference

12 December 2020

Mutations at arginine 352 alter the pore architecture of CFTR.

1 reference

12 December 2020

Atomic model of human cystic fibrosis transmembrane conductance regulator: membrane-spanning domains and coupling interfaces

1 reference

12 December 2020

Evolutionary and functional divergence between the cystic fibrosis transmembrane conductance regulator and related ATP-binding cassette transporters

1 reference

12 December 2020

Clinical practice and genetic counseling for cystic fibrosis and CFTR-related disorders

1 reference

12 December 2020

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

1 reference

12 December 2020

Gating of the CFTR Cl- channel by ATP-driven nucleotide-binding domain dimerisation

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12 December 2020

Novel residues lining the CFTR chloride channel pore identified by functional modification of introduced cysteines

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12 December 2020

Molecular models of the open and closed states of the whole human CFTR protein

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12 December 2020

Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore

1 reference

12 December 2020

Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore

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12 December 2020

Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel

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12 December 2020

Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation

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12 December 2020

Molecular modeling tools and approaches for CFTR and cystic fibrosis

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12 December 2020

Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant.

1 reference

12 December 2020

Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7).

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12 December 2020

Differential contribution of TM6 and TM12 to the pore of CFTR identified by three sulfonylurea-based blockers

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12 December 2020

Conformational change opening the CFTR chloride channel pore coupled to ATP-dependent gating

1 reference

12 December 2020

Alternating access to the transmembrane domain of the ATP-binding cassette protein cystic fibrosis transmembrane conductance regulator (ABCC7).

1 reference

12 December 2020

Cystic fibrosis transmembrane conductance regulator: a molecular model defines the architecture of the anion conduction path and locates a "bottleneck" in the pore

1 reference

12 December 2020

Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation

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12 December 2020

New model of cystic fibrosis transmembrane conductance regulator proposes active channel-like conformation.

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12 December 2020

Locating a plausible binding site for an open-channel blocker, GlyH-101, in the pore of the cystic fibrosis transmembrane conductance regulator.

1 reference

12 December 2020

Nonequilibrium gating of CFTR on an equilibrium theme

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12 December 2020

The CFTR ion channel: gating, regulation, and anion permeation

1 reference

12 December 2020

Cysteine scanning of CFTR's first transmembrane segment reveals its plausible roles in gating and permeation

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12 December 2020

Relative contribution of different transmembrane segments to the CFTR chloride channel pore.

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12 December 2020

Catalyst-like modulation of transition states for CFTR channel opening and closing: new stimulation strategy exploits nonequilibrium gating

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12 December 2020

Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog

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12 December 2020

Revisiting CFTR inhibition: a comparative study of CFTRinh -172 and GlyH-101 inhibitors

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12 December 2020

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

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12 December 2020

Full-open and closed CFTR channels, with lateral tunnels from the cytoplasm and an alternative position of the F508 region, as revealed by molecular dynamics

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12 December 2020

Contribution of proline residues in the membrane-spanning domains of cystic fibrosis transmembrane conductance regulator to chloride channel function

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12 December 2020

Glibenclamide blockade of CFTR chloride channels.

1 reference

12 December 2020

Locating the anion-selectivity filter of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel.

1 reference

12 December 2020

Mechanism of glibenclamide inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a murine cell line

1 reference

12 December 2020

Cystic fibrosis transmembrane conductance regulator (CFTR) anion binding as a probe of the pore

1 reference

12 December 2020

Channel-lining residues in the M3 membrane-spanning segment of the cystic fibrosis transmembrane conductance regulator.

1 reference

12 December 2020

10.1021/ACS.BIOCHEM.5B00427

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6510985&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6510985&resulttype=core&format=json

14 May 2020

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