Comparative pharmacokinetics of antiviral nucleoside analogues (Q40886850)

24 September 2017

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title

Comparative pharmacokinetics of antiviral nucleoside analogues (English)

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24 September 2017

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G D Morse

1

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24 September 2017

M J Shelton

series ordinal

2

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24 September 2017

A M O'Donnell

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3

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24 September 2017

1 February 1993

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Clinical Pharmacokinetics

24 September 2017

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24 September 2017

24

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24 September 2017

101-123

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24 September 2017

2

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https://scigraph.springernature.com/pub.10.2165/00003088-199324020-00002

24 September 2017

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Intracellular zidovudine (ZDV) and ZDV phosphates as measured by a validated combined high-pressure liquid chromatography-radioimmunoassay procedure

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Pharmacokinetics of acyclovir suspension in infants and children

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12 December 2020

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Hemodialysis clearance of intravenously administered ribavirin

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Pharmacokinetics of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine in patients with severe human immunodeficiency virus infection

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12 December 2020

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12 December 2020

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12 December 2020

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Zidovudine disposition in patients with severe renal impairment: influence of hemodialysis

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12 December 2020

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12 December 2020

Pharmacokinetics of oral zidovudine (azidothymidine) in patients with AIDS when administered with and without a high-fat meal

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12 December 2020

Metabolism of arabinosyladenine in herpes simplex virus-infected and uninfected cells. Correlation with inhibition of DNA synthesis and role in antiviral selectivity

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12 December 2020

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12 December 2020

Pharmacokinetics and long-term tolerance to ribavirin in asymptomatic patients infected with human immunodeficiency virus

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12 December 2020

Pharmacokinetics of orally administered zidovudine among patients with hemophilia and asymptomatic human immunodeficiency virus (HIV) infection

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12 December 2020

Effect of liver disease on pharmacokinetics and toxicity of 9-beta-D-arabinofuranosyladenine-5-phosphate

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12 December 2020

Ribavirin disposition in high-risk patients for acquired immunodeficiency syndrome.

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12 December 2020

Fetoplacental passage of 2',3'-dideoxyinosine

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12 December 2020

Human gastrointestinal absorption of acyclovir from tablet duodenal infusion and sipped solution

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12 December 2020

Dideoxycytidine permeation and salvage by mouse leukemia cells and human erythrocytes

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12 December 2020

Human pharmacokinetics of acyclovir (an antiviral agent) following rapid intravenous injection

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12 December 2020

Pharmacokinetics of vidarabine in the treatment of infants and children with infections due to herpesviruses

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12 December 2020

Antiviral activity and mechanism of action of ganciclovir

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12 December 2020

Evaluation of saliva as a specimen for monitoring zidovudine therapy in HIV-infected patients

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12 December 2020

Pharmacokinetics of zidovudine in a patient on maintenance hemodialysis

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12 December 2020

Acyclovir in human breast milk

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12 December 2020

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12 December 2020

The disposition and metabolism of 2',3'-dideoxycytidine, an in vitro inhibitor of human T-lymphotrophic virus type III infectivity, in mice and monkeys

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12 December 2020

Food-induced reduction in bioavailability of didanosine.

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12 December 2020

In vitro measurement of phosphorylated zidovudine in peripheral blood leucocytes

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12 December 2020

Dideoxycytidine alone and in an alternating schedule with zidovudine in children with symptomatic human immunodeficiency virus infection

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12 December 2020

Activity of 9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine in the treatment of cytomegalovirus pneumonia

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12 December 2020

Intravenous and oral zidovudine pharmacokinetics and coagulation effects in asymptomatic human immunodeficiency virus-infected hemophilia patients

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12 December 2020

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12 December 2020

Probenecid and zidovudine metabolism

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12 December 2020

HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

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12 December 2020

Acyclovir concentrations in serum and cerebrospinal fluid at steady state

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12 December 2020

Dideoxyinosine in Children with Symptomatic Human Immunodeficiency Virus Infection

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12 December 2020

Drugs five years later: acyclovir

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12 December 2020

The role of cytoplasmic deoxycytidine kinase in the mitochondrial effects of the anti-human immunodeficiency virus compound, 2‘,3‘-dideoxycytidine

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12 December 2020

Inhibition of purified human and herpes simplex virus-induced DNA polymerases by 9-(2-hydroxyethoxymethyl)guanine triphosphate. Effects on primer-template function

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12 December 2020

Pharmacodynamics of 2′,3′-dideoxycytidine: An inhibitor of human immunodeficiency virus

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12 December 2020

Herpes simplex encephalitis: vidarabine therapy and diagnostic problems

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12 December 2020

Once-daily administration of 2',3'-dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex. Results of a Phase I trial

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12 December 2020

Metabolic pathways for the activation of the antiretroviral agent 2',3'-dideoxyadenosine in human lymphoid cells

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12 December 2020

2',3'-dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex. A phase I trial

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12 December 2020

Pharmacokinetics of zidovudine administered intravenously and orally in children with human immunodeficiency virus infection.

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12 December 2020

The pharmacokinetics of zidovudine administered by continuous infusion in children

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12 December 2020

Inhibition by acyclovir of cell growth and DNA synthesis of cells biochemically transformed with Herpesvirus genetic information

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12 December 2020

Studies of 9-beta-D-arabinofuranosyladenine in man

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12 December 2020

Adenine arabinoside and allopurinol--possible adverse drug interaction

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12 December 2020

The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

1 reference

12 December 2020

Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2',3'-dideoxycytidine

1 reference

12 December 2020

Phosphorylation of the antiviral precursor 9-(1,3-dihydroxy-2-propoxymethyl)guanine monophosphate by guanylate kinase isozymes

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12 December 2020

Cellular metabolism of 2',3'-dideoxycytidine, a compound active against human immunodeficiency virus in vitro

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12 December 2020

Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy

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12 December 2020

Disposition of intravenous radioactive acyclovir

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12 December 2020

Pancreatitis and pancreatic dysfunction in patients taking dideoxyinosine

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12 December 2020

A pilot study of the bioavailability and pharmacokinetics of 2',3'-dideoxycytidine in patients with AIDS or AIDS-related complex

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12 December 2020

Comparative pharmacokinetics of zidovudine (AZT) and its metabolite (G.AZT) in healthy subjects and HIV seropositive patients

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12 December 2020

Activity of 9-(1,3-dihydroxy-2-propoxymethyl)guanine compared with that of acyclovir against human, monkey, and rodent cytomegaloviruses

1 reference

12 December 2020

The effect of acetaminophen on zidovudine metabolism in HIV-infected patients

1 reference

12 December 2020

Inhibition of herpes simplex virus transformed and nontransformed cells by acycloguanosine: Mechanisms of uptake and toxicity

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12 December 2020

Ribavirin enters cerebrospinal fluid.

1 reference

12 December 2020

Initial studies on the cellular pharmacology of 2',3-dideoxycytidine, an inhibitor of HTLV-III infectivity.

1 reference

12 December 2020

Impact of bioavailability on determination of the maximal tolerated dose of 2',3'-dideoxyinosine in phase I trials

1 reference

12 December 2020

Pharmacology, Tolerance, and Antiviral Activity of Vidarabine Monophosphate in Humans

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12 December 2020

Multiple-dose pharmacokinetics of oral zidovudine in hemophilia patients with human immunodeficiency virus infection

1 reference

12 December 2020

2',3'-Dideoxycytidine: regulation of its metabolism and anti-retroviral potency by natural pyrimidine nucleosides and by inhibitors of pyrimidine nucleotide synthesis

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12 December 2020

Influence of hemodialysis on acyclovir pharmacokinetics in patients with chronic renal failure

1 reference

12 December 2020

Unexpected accumulation of acyclovir in breast milk with estimation of infant exposure

1 reference

12 December 2020

Fetoplacental passage of zidovudine

1 reference

12 December 2020

Effects of probenecid on the pharmacokinetics and elimination of acyclovir in humans

1 reference

12 December 2020

Growth Inhibition by Acycloguanosine of Herpesviruses Isolated from Human Infections

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12 December 2020

Strategies for antiviral therapy in AIDS.

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12 December 2020

Initial studies on the cellular pharmacology of 2',3'-dideoxyadenosine, an inhibitor of HTLV-III infectivity

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12 December 2020

Acyclovir malabsorption.

1 reference

12 December 2020

A review of the pharmacokinetics of zidovudine in man.

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12 December 2020

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro

1 reference

12 December 2020

The metabolism of ribavirin in erythrocytes and nucleated cells

1 reference

12 December 2020

Ribavirin pharmacodynamics in high-risk patients for acquired immunodeficiency syndrome.

1 reference

12 December 2020

Pharmacokinetics of acyclovir in the term human pregnancy and neonate

1 reference

12 December 2020

Phosphorylation of 2',3'-dideoxyinosine by cytosolic 5'-nucleotidase of human lymphoid cells

1 reference

12 December 2020

Enzymatic phosphorylation of acyclic nucleoside analogs and correlations with antiherpetic activities

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12 December 2020

Circulating p24 antigen levels and responses to dideoxycytidine in human immunodeficiency virus (HIV) infections. A phase I and II study

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12 December 2020

10.2165/00003088-199324020-00002

Identifiers

DOI

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Dimensions Publication ID

24 September 2017

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