Conserved Ca2+-antagonist-binding properties and putative folding structure of a recombinant high-affinity dihydropyridine-binding domain. (Q40886220)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10769189%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Conserved Ca2+-antagonist-binding properties and putative folding structure of a recombinant high-affinity dihydropyridine-binding domain (English)

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5 November 2019

5

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5 November 2019

Thierry Langer

6

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5 November 2019

Joerg Striessnig

7

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5 November 2019

author name string

Huber I

1

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5 November 2019

Wappl E

2

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5 November 2019

Herzog A

3

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5 November 2019

Mitterdorfer J

4

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5 November 2019

language of work or name

English

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publication date

1 May 2000

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5 November 2019

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5 November 2019

volume

347 Pt 3

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5 November 2019

page(s)

829-836

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Transmembrane structure of an inwardly rectifying potassium channel

5 November 2019

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Familial hemiplegic migraine mutations change alpha1A Ca2+ channel kinetics

24 September 2017

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Construction of a high-affinity receptor site for dihydropyridine agonists and antagonists by single amino acid substitutions in a non-L-type Ca2+ channel

24 September 2017

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Nine L-type amino acid residues confer full 1,4-dihydropyridine sensitivity to the neuronal calcium channel alpha1A subunit. Role of L-type Met1188.

24 September 2017

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Molecular determinants of drug binding and action on L-type calcium channels

24 September 2017

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Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor

24 September 2017

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24 September 2017

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Structure and function of voltage-gated ion channels

24 September 2017

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Voltage-dependent blockade of diverse types of voltage-gated Ca2+ channels expressed in Xenopus oocytes by the Ca2+ channel antagonist mibefradil (Ro 40-5967)

24 September 2017

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A prokaryotic potassium ion channel with two predicted transmembrane segments from Streptomyces lividans

24 September 2017

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

24 September 2017

1 reference

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(+)-Niguldipine binds with very high affinity to Ca2+ channels and to a subtype of alpha 1-adrenoceptors

24 September 2017

1 reference

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Pursuing the structure and function of voltage-gated channels

24 September 2017

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Transfer of the high affinity dihydropyridine sensitivity from L-type To non-L-type calcium channel.

24 September 2017

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Alternatively spliced IS6 segments of the alpha 1C gene determine the tissue-specific dihydropyridine sensitivity of cardiac and vascular smooth muscle L-type Ca2+ channels

25 September 2017

1 reference

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The IVS6 segment of the L-type calcium channel is critical for the action of dihydropyridines and phenylalkylamines.

25 September 2017

1 reference

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Analysis of the dihydropyridine receptor site of L-type calcium channels by alanine-scanning mutagenesis

25 September 2017

1 reference

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Transmembrane auxiliary subunits of voltage-dependent ion channels

25 September 2017

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Calcium channels: the beta-subunit increases the affinity of dihydropyridine and Ca2+ binding sites of the alpha 1-subunit.

25 September 2017

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Beta subunit heterogeneity in neuronal L-type Ca2+ channels.

25 September 2017

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Transfer of high sensitivity for benzothiazepines from L-type to class A (BI) calcium channels.

17 June 2018

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Biochemical characterization of a 22-kDa high affinity antiischemic drug-binding polypeptide in the endoplasmic reticulum of guinea pig liver: potential common target for antiischemic drug action.

17 June 2018

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Distinct calcium channels are generated by alternative splicing and are differentially expressed in the mammalian CNS

17 June 2018

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Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves

17 June 2018

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Molecular mechanism of diltiazem interaction with L-type Ca2+ channels.

17 June 2018

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Two amino acid residues in the IIIS5 segment of L-type calcium channels differentially contribute to 1,4-dihydropyridine sensitivity.

19 August 2018

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Human red-blood-cell Ca2+-antagonist binding sites. Evidence for an unusual receptor coupled to the nucleoside transporter

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12 December 2020

Purified calcium channels have three allosterically coupled drug receptors

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12 December 2020

Interaction of tetrandrine with slowly inactivating calcium channels. Characterization of calcium channel modulation by an alkaloid of Chinese medicinal herb origin

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12 December 2020

Identification of a 27-kDa high affinity phenylalkylamine-binding polypeptide as the sigma 1 binding site by photoaffinity labeling and ligand-directed antibodies

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12 December 2020

The naming of voltage-gated calcium channels

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12 December 2020

Complex molecular mechanism for dihydropyridine binding to L-type Ca(2+)-channels as revealed by fluorescence resonance energy transfer

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12 December 2020

Subunit composition is a major determinant in high affinity binding of a Ca2+ channel blocker

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12 December 2020

L-type calcium channels: binding domains for dihydropyridines and benzothiazepines are located in close proximity to each other

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12 December 2020

Structural basis of drug binding to L Ca2+ channels

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12 December 2020

10.1042/0264-6021:3470829

Identifiers

DOI

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24 September 2017

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5 November 2019

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5 November 2019

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