HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300. (Q40879241)

24 September 2017

HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300. (English)

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Human T-lymphotropic virus 1

24 September 2017

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author name string

C Nicot

1

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24 September 2017

R Mahieux

2

1 reference

24 September 2017

R Opavsky

3

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24 September 2017

A Cereseto

4

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24 September 2017

L Wolff

5

1 reference

24 September 2017

J N Brady

6

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24 September 2017

G Franchini

7

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24 September 2017

language of work or name

English

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publication date

1 April 2000

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24 September 2017

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24 September 2017

19

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24 September 2017

2155-2164

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24 September 2017

17

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203536

24 September 2017

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Limiting amounts of p27Kip1 correlates with constitutive activation of cyclin E-CDK2 complex in HTLV-I-transformed T-cells

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The EVES motif mediates both intermolecular and intramolecular regulation of c-Myb

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Myb binding sites within the N-ras promoter repress transcription

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An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300

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c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiation

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HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase gene

21 January 2018

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Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1

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PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner

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Myb-interacting protein, ATBF1, represses transcriptional activity of Myb oncoprotein

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Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation

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Repression of the c-myb gene by WT1 protein in T and B cell lines

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Interaction of C/EBPbeta and v-Myb is required for synergistic activation of the mim-1 gene

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The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells

21 January 2018

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Differential binding of nuclear factors to the intron 1 sequences containing the transcriptional pause site correlates with c-myb expression

21 January 2018

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Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes

21 January 2018

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21 January 2018

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Molecular cloning reveals that the p160 Myb-binding protein is a novel, predominantly nucleolar protein which may play a role in transactivation by Myb

21 January 2018

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Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation

21 January 2018

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Myb: an old oncoprotein with new roles

21 January 2018

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7 January 2021

The human T-cell leukemia virus type 1 oncoprotein Tax inhibits the transcriptional activity of c-Myb through competition for the CREB binding protein.

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CBP as a transcriptional coactivator of c-Myb

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G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb

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Single amino acid substitution (58Pro-->Ser) in HTLV-I tax results in loss of ras cooperative focus formation in rat embryo fibroblasts

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7 January 2021

Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203536

1 reference

Dimensions Publication ID

24 September 2017

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1 reference