Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2. (Q40878349)

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English	Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 September 2017

Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2. (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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author name string

I Rafiq

1

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Europe PubMed Central

PubMed publication ID

24 September 2017

G da Silva Xavier

2

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Europe PubMed Central

PubMed publication ID

24 September 2017

S Hooper

3

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Europe PubMed Central

PubMed publication ID

24 September 2017

G A Rutter

4

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Europe PubMed Central

PubMed publication ID

24 September 2017

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publication date

1 May 2000

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Europe PubMed Central

PubMed publication ID

24 September 2017

number of pages

8

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

24 September 2017

275

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Europe PubMed Central

PubMed publication ID

24 September 2017

21

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Europe PubMed Central

PubMed publication ID

24 September 2017

15977-15984

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Europe PubMed Central

PubMed publication ID

24 September 2017

Electrophysiology of the pancreatic beta-cell

1 reference

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21 January 2018

Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways

1 reference

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The effect of sugars on (pro)insulin biosynthesis

1 reference

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Effects of D-glucose, L-leucine, and 2-ketoisocaproate on insulin mRNA levels in mouse pancreatic islets

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21 January 2018

The insulin gene promoter. A simplified nomenclature.

1 reference

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Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells

1 reference

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21 January 2018

Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes

1 reference

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21 January 2018

Glucose modulates the binding activity of the beta-cell transcription factor IUF1 in a phosphorylation-dependent manner

1 reference

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Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells

1 reference

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The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

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Glucose-dependent translocation of insulin promoter factor-1 (IPF-1) between the nuclear periphery and the nucleoplasm of single MIN6 beta-cells

1 reference

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21 January 2018

Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells

1 reference

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21 January 2018

The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway

1 reference

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21 January 2018

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

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Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain

1 reference

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Glucose stimulates the activation domain potential of the PDX-1 homeodomain transcription factor

1 reference

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21 January 2018

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 reference

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21 January 2018

Subcellular imaging of intramitochondrial Ca2+ with recombinant targeted aequorin: significance for the regulation of pyruvate dehydrogenase activity

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21 January 2018

Upstream stimulatory factor-2 (USF2) activity is required for glucose stimulation of L-pyruvate kinase promoter activity in single living islet beta-cells.

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21 January 2018

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

1 reference

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21 January 2018

Transcription factor ATF2 regulation by the JNK signal transduction pathway

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21 January 2018

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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21 January 2018

Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion

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21 January 2018

Activation of the novel MAP kinase homologue SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6).

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21 January 2018

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

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21 January 2018

Insulin receptor signaling in the beta-cell influences insulin gene expression and insulin content: evidence for autocrine beta-cell regulation

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21 January 2018

Insulin secretion: feed-forward control of insulin biosynthesis?

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Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase

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A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

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Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells. Potential role for strategically located mitochondria.

1 reference

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21 January 2018

Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells

1 reference

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21 January 2018

The role of PI 3-kinase in insulin action

1 reference

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21 January 2018

Translational control of proinsulin synthesis by glucose

1 reference

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21 January 2018

Identifiers

10.1074/JBC.275.21.15977

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

ResearchGate publication ID

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