Oncogenes and tumour suppressor genes in transgenic mouse models of neoplasia (Q40877342)

24 September 2017

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title

Oncogenes and tumour suppressor genes in transgenic mouse models of neoplasia (English)

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24 September 2017

Fowlis DJ

1

1 reference

PubMed ID

8435223

24 September 2017

Balmain A

series ordinal

2

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24 September 2017

1 January 1993

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European Journal of Cancer

24 September 2017

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24 September 2017

29A

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24 September 2017

4

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24 September 2017

638-645

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The molecular genetics of cancer

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Oncogene activation in chemical carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Transgenic mice as probes into complex systems

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Transgenic models of tumor development.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Cooperation between oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Raf-1 activates MAP kinase-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Acute leukaemia in bcr/abl transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Leukemia and the disruption of normal hematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Oncogene activation in human benign tumors of the skin (keratoacanthomas): is HRAS involved in differentiation as well as proliferation?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Spontaneous Ha-ras gene activation in cultured primary murine keratinocytes: consequences of Ha-ras gene activation in malignant conversion and malignant progression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Abnormalities of epidermal differentiation associated with expression of the human papillomavirus type 1 early region in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

The int-2 gene product acts as an epithelial growth factor in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Ha-ras and c-myc oncogene expression interferes with morphological and functional differentiation of mammary epithelial cells in single and double transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Mutational hot spot in the p53 gene in human hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Transgenic mice carrying the mouse mammary tumor virus ras fusion gene: distinct effects in various tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Expression of SV-40 T antigen in the small intestinal epithelium of transgenic mice results in proliferative changes in the crypt and reentry of villus-associated enterocytes into the cell cycle but has no apparent effect on cellular differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Pulmonary carcinogenesis in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Thyroid adenocarcinomas secondary to tissue-specific expression of simian virus-40 large T-antigen in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Renin promoter SV40 T-antigen transgenic mouse. A model of primary renal vascular hyperplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Restriction of neuroblastoma to the prostate gland in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Tumor suppressor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Loss of constitutional heterozygosity in human cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

The new mouse genetics: altering the genome by gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

p53 function and dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980170-4

7 January 2021

10.1016/S0959-8049(05)80170-4

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

8435223