Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK. (Q40867080)

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scientific article published on November 2000

Language	Label	Description	Also known as
English	Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK.	scientific article published on November 2000

Statements

scholarly article

1 reference

Europe PubMed Central

24 September 2017

Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK. (English)

1 reference

Europe PubMed Central

24 September 2017

author name string

G Xiao

1

1 reference

Europe PubMed Central

24 September 2017

E W Harhaj

2

1 reference

Europe PubMed Central

24 September 2017

S C Sun

3

1 reference

Europe PubMed Central

24 September 2017

language of work or name

0 references

publication date

1 November 2000

1 reference

Europe PubMed Central

24 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

24 September 2017

275

1 reference

Europe PubMed Central

24 September 2017

34060-34067

1 reference

Europe PubMed Central

24 September 2017

44

1 reference

Europe PubMed Central

24 September 2017

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

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Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

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Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulation

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The x gene is essential for HTLV replication.

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A transcriptional activator protein encoded by the x-lor region of the human T-cell leukemia virus

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Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer

1 reference

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Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction

1 reference

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21 January 2018

The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.

1 reference

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HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization

1 reference

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Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax.

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Recognition of bZIP proteins by the human T-cell leukaemia virus transactivator Tax.

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Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP.

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Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300

1 reference

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An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300

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PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner

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Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia

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Function and activation of NF-kappa B in the immune system

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The NF-kappa B and I kappa B proteins: new discoveries and insights

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Signal transduction through NF-kappa B.

1 reference

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How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

1 reference

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HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation.

1 reference

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21 January 2018

NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation

1 reference

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21 January 2018

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases

1 reference

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21 January 2018

Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases

1 reference

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21 January 2018

Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene

1 reference

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Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

1 reference

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Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002970200

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002970200

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

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IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

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Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

1 reference

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MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

1 reference

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Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

1 reference

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Recombinant IkappaB kinases alpha and beta are direct kinases of Ikappa Balpha

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Ionizing radiation activates the ATM kinase throughout the cell cycle

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Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

1 reference

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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

1 reference

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Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

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Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

1 reference

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Activation of IkappaB kinase beta by protein kinase C isoforms

1 reference

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The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbeta

1 reference

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IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

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Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

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IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

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Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation

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I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

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Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes

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Identifiers

10.1074/JBC.M002970200

1 reference

Europe PubMed Central

24 September 2017

1 reference

Europe PubMed Central

24 September 2017

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