An oncogenic epidermal growth factor receptor signals via a p21-activated kinase-caldesmon-myosin phosphotyrosine complex (Q40859402)

24 September 2017

An oncogenic epidermal growth factor receptor signals via a p21-activated kinase-caldesmon-myosin phosphotyrosine complex (English)

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24 September 2017

5

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24 September 2017

M J McManus

1

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24 September 2017

J L Boerner

2

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24 September 2017

A J Danielsen

3

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24 September 2017

Z Wang

4

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24 September 2017

N J Maihle

6

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24 September 2017

language of work or name

English

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publication date

1 November 2000

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Journal of Biological Chemistry

24 September 2017

7

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based on heuristic

inferred from page(s)

published in

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24 September 2017

275

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24 September 2017

35328-35334

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24 September 2017

45

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

24 September 2017

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Oncogenic activation of tyrosine kinases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

A transformation-associated complex involving tyrosine kinase signal adapter proteins and caldesmon links v-erbB signaling to actin stress fiber disassembly

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Ras-independent transformation by v-Src

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Inhibition of myosin light chain kinase by p21-activated kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Association of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligand

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Multiple gene products are produced from a novel protein kinase transcription region.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Tyrosine Phosphorylation of Caldesmon Is Required for Binding to the Shc⋅Grb2 Complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Caldesmon inhibits nonmuscle cell contractility and interferes with the formation of focal adhesions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Molecular mechanisms of nonmuscle myosin-II regulation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Structural alterations of the epidermal growth factor receptor gene in human gliomas

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Genetic evidence for Pak1 autoinhibition and its release by Cdc42.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

From molecular to modular cell biology

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Cellular control lies in the balance of forces

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

The structural and mechanical complexity of cell-growth control

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Human platelet myosin. I. Purification by a rapid method applicable to other nonmuscle cells.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Effects of pH, ionic strength, and temperature on activation by calmodulin an catalytic activity of myosin light chain kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Autophosphorylation of smooth muscle myosin light chain kinase at its regulatory domain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005399200

Phosphorylation of caldesmon by p21-activated kinase. Implications for the Ca(2+) sensitivity of smooth muscle contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005399200

21 January 2018

Identifiers

DOI

10.1074/JBC.M005399200

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24 September 2017

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