Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase (Q40858827)

24 September 2017

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title

Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase (English)

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24 September 2017

1

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24 September 2017

Katze MG

2

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24 September 2017

1 April 1998

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Pharmacology & Therapeutics

24 September 2017

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24 September 2017

78

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24 September 2017

29-46

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24 September 2017

1

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Expression of cellular genes in CD4 positive lymphoid cells infected by the human immunodeficiency virus, HIV-1: evidence for a host protein synthesis shut-off induced by cellular mRNA degradation

24 September 2017

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7 January 2021

Interferon treatment inhibits virus replication in HIV-1- and SIV-infected CD4+ T-cell lines by distinct mechanisms: evidence for decreased stability and aberrant processing of HIV-1 proteins

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7 January 2021

Early events in Epstein-Barr virus infection of human B lymphocytes

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7 January 2021

Nucleocytoplasmic transport: the influenza virus NS1 protein regulates the transport of spliced NS2 mRNA and its precursor NS1 mRNA.

1 reference

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7 January 2021

Epidemiology of hepatitis C in the West

1 reference

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7 January 2021

The mouse antiphosphotyrosine immunoreactive kinase, TIK, is indistinguishable from the double-stranded RNA-dependent, interferon-induced protein kinase, PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Functional expression and characterization of the interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Vaccinia virus-encoded elF-2α homolog abrogates the antiviral effect of interferon

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Distinct patterns of IFN sensitivity observed in cells infected with vaccinia K3L- and E3L- mutant viruses

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Host-range restriction of vaccinia virus E3L-specific deletion mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Two small RNAs encoded by Epstein-Barr virus can functionally substitute for the virus-associated RNAs in the lytic growth of adenovirus 5

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Construction and analysis of additional adenovirus substitution mutants confirm the complementation of VAI RNA function by two small RNAs encoded by Epstein-Barr virus

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Characterization of two murine (2'-5')(A)n-dependent endonucleases of different molecular mass

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Degradation of the interferon-induced 68,000-M(r) protein kinase by poliovirus requires RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Identification of a conserved motif that is necessary for binding of the vaccinia virus E3L gene products to double-stranded RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Accessing genetic information with high-density DNA arrays.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Translational control by the Epstein-Barr virus small RNA EBER-1. Reversal of the double-stranded RNA-induced inhibition of protein synthesis in reticulocyte lysates

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Binding of Epstein-Barr virus small RNA EBER-1 to the double-stranded RNA-activated protein kinase DAI.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The small RNAs of Epstein-Barr virus

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The double-stranded RNA-dependent protein kinase PKR: structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

PKR: proposed nomenclature for the RNA-dependent protein kinase induced by interferon.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Regulation of the interferon-inducible eIF-2 alpha protein kinase by small RNAs.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Double-stranded RNA in Vaccinia Virus Infected Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The kinase insert domain of interferon-induced protein kinase PKR is required for activity but not for interaction with the pseudosubstrate K3L

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Protein synthesis in different cell lines infected with orthoreovirus serotype 3: inhibition of host-cell protein synthesis correlates with accelerated viral multiplication and cell killing

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The vaccinia virus K3L gene product potentiates translation by inhibiting double-stranded-RNA-activated protein kinase and phosphorylation of the alpha subunit of eukaryotic initiation factor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3' untranslated regions of human alpha-tropomyosin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Site-directed mutagenic analysis of reovirus sigma 3 protein binding to dsRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Successors to acyclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: a novel translational control mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Regulation of the double-stranded RNA-dependent protein kinase PKR by RNAs encoded by a repeated sequence in the Epstein-Barr virus genome

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Interferons in the persistence, pathogenesis, and treatment of HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Therapy of hepatitis C.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The binding of double-stranded RNA and adenovirus VAI RNA to the interferon-induced protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Interaction of the interferon-induced PKR protein kinase with inhibitory proteins P58IPK and vaccinia virus K3L is mediated by unique domains: implications for kinase regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Binding of the adenovirus VAI RNA to the interferon-induced 68-kDa protein kinase correlates with function

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Stimulation of chloramphenicol acetyltransferase mRNA translation by reovirus capsid polypeptide sigma 3 in cotransfected COS cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The complete DNA sequence of vaccinia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The TPR snap helix: a novel protein repeat motif from mitosis to transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Binding of influenza A virus NS1 protein to dsRNA in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Sequence and regulation of a gene encoding a human 89-kilodalton heat shock protein

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The eIF-2 alpha kinases: regulators of protein synthesis in starvation and stress

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Physical and functional characterization of the double-stranded RNA binding protein encoded by the vaccinia virus E3 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Reovirus-coded polypeptides in infected cells: Isolation of two native monomeric polypeptides with affinity for single-stranded and double-stranded RNA, respectively

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Current state of interferon therapy for chronic hepatitis C.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Inhibitory activity for the interferon-induced protein kinase is associated with the reovirus serotype 1 sigma 3 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The Lang strain of reovirus serotype 1 and the Dearing strain of reovirus serotype 3 differ in their sensitivities to beta interferon

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The interferon system: a review with emphasis on the role of PKR in growth control

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

A conserved double-stranded RNA-binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Regulation of the interferon-induced PKR: can viruses cope?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Regulation of Viral and Cellular RNA Turnover in Cells Infected by Eukaryotic Viruses including HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Influenza virus regulates protein synthesis during infection by repressing autophosphorylation and activity of the cellular 68,000-Mr protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Involvement of the IRF-1 transcription factor in antiviral responses to interferons

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Regulation of the protein kinase PKR by the vaccinia virus pseudosubstrate inhibitor K3L is dependent on residues conserved between the K3L protein and the PKR substrate eIF2alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The interferon-inducible protein kinase PKR modulates the transcriptional activation of immunoglobulin kappa gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Cloning, expression, and cellular localization of the oncogenic 58-kDa inhibitor of the RNA-activated human and mouse protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Tetratrico peptide repeat interactions: to TPR or not to TPR?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Diversity of coding strategies in influenza viruses

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Immunology of HIV Infection, I: Biology of the Interferons

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The apoptosis pathway triggered by the interferon-induced protein kinase PKR requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Cellular inhibitors of the interferon-induced, dsRNA-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Expression of the cloned S4 gene of reovirus serotype 3 in transformed eucaryotic cells: enrichment of the viral protein in the crude initiation factor fraction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Activation of the double-stranded RNA-dependent eIF-2alpha kinase by cellular RNA from 3T3-F442A cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Translational stimulation by reovirus polypeptide sigma 3: substitution for VAI RNA and inhibition of phosphorylation of the alpha subunit of eukaryotic initiation factor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Expression monitoring by hybridization to high-density oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Interactions between double-stranded RNA regulators and the protein kinase DAI

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Characterization of the double-stranded RNA implicated in the inhibition of protein synthesis in cells infected with a mutant adenovirus defective for VA RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Blockage of NF-kappa B signaling by selective ablation of an mRNA target by 2-5A antisense chimeras

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Mechanism of interferon action: RNA-binding activity of full-length and R-domain forms of the RNA-dependent protein kinase PKR--determination of KD values for VAI and TAR RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The nature of the polypeptide encoded by each of the 10 double-stranded RNA segments of reovirus type 3

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

HIV-1 Tat directly interacts with the interferon-induced, double-stranded RNA-dependent kinase, PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Interaction of adenovirus VA RNAl with the protein kinase DAI: nonequivalence of binding and function.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Mechanisms for the inhibition of HIV replication by interferons-alpha, -beta, and -gamma in primary human macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Proteolytic cleavage of the reovirus sigma 3 protein results in enhanced double-stranded RNA-binding activity: identification of a repeated basic amino acid motif within the C-terminal binding region

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Functional role of type I and type II interferons in antiviral defense

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate early gene induction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

A mechanism for the control of protein synthesis by adenovirus VA RNAI.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Mechanism of interferon action. Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The antiviral potentials of Mx proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Interferons and their actions

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Characterization and mapping of the double-stranded regions involved in activation of PKR within a cellular RNA from 3T3-F442A cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Multiple Effects of Interferon on HIV-1 Replication

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Interferon-alpha but not AZT suppresses HIV expression in chronically infected cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The P58 cellular inhibitor complexes with the interferon-induced, double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Differentiation of the shutoff of protein synthesis by virion host shutoff and mutant gamma (1)34.5 genes of herpes simplex virus 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

PKR: a new name and new roles.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A)

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

A human homologue of theEscherichia coliDnaJ heatshock protein

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Control of the interferon-induced 68-kilodalton protein kinase by the HIV-1 tat gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The integrity of the stem structure of human immunodeficiency virus type 1 Tat-responsive sequence of RNA is required for interaction with the interferon-induced 68,000-Mr protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Distinct binding sites for zinc and double-stranded RNA in the reovirus outer capsid protein sigma 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Preferential translation of reovirus mRNA by a sigma3-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Translational effects and sequence comparisons of the three serotypes of the reovirus S4 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Comparative analysis of the regulation of the interferon-inducible protein kinase PKR by Epstein-Barr virus RNAs EBER-1 and EBER-2 and adenovirus VAI RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Reovirus inhibition of cellular RNA and protein synthesis: Role of the S4 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Translational control by adenovirus: lack of virus-associated RNAI during adenovirus infection results in phosphorylation of initiation factor eIF-2 and inhibition of protein synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Eukaryotic DnaJ homologs and the specificity of Hsp70 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Fascination with 2-5A-dependent RNase: a unique enzyme that functions in interferon action

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Control of the ppp(a2'p)nA system in HeLa cells. Effects of interferon and virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Cloning and characterization of a human protein phosphatase 1-encoding cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Anti-HIV-1 activity of recombinant and hybrid species of interferon-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Calcium depletion from the endoplasmic reticulum activates the double-stranded RNA-dependent protein kinase (PKR) to inhibit protein synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Interferon-induced proteins and the antiviral state.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Simian virus 40 large-T bypasses the translational block imposed by the phosphorylation of elF-2 alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Mechanism of interferon action: structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

A template for the protein kinase family

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Mechanism of interferon action: characterization of the intermolecular autophosphorylation of PKR, the interferon-inducible, RNA-dependent protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Mechanism of interferon action: cDNA structure, expression, and regulation of the interferon-induced, RNA-dependent P1/eIF-2 alpha protein kinase from human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Characterization of a vaccinia virus-encoded double-stranded RNA-binding protein that may be involved in inhibition of the double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Characterization of a specific kinase inhibitory factor produced by vaccinia virus which inhibits the interferon-induced protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The role of the dsRNA-activated kinase, PKR, in signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Double-stranded RNA-dependent protein kinase (PKR) is regulated by reovirus structural proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Ribosome targeting of PKR is mediated by two double-stranded RNA-binding domains and facilitates in vivo phosphorylation of eukaryotic initiation factor-2

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

Studies on the intracellular synthesis of reovirus-specified proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900165-4

7 January 2021

10.1016/S0163-7258(97)00165-4

Identifiers

DOI

1 reference

release_rirktmakazgebo7ob4jhjae2xe

24 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rirktmakazgebo7ob4jhjae2xe

24 November 2022

mapped directly with Wikidata item

PubMed ID

9593328

1 reference

PubMed ID

9593328