DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective. (Q40789656)

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English	DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective.	scientific article

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21 October 2019

DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective (English)

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21 October 2019

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apoptotic process

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4

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21 October 2019

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21 October 2019

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Allday MJ

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21 October 2019

Crawford DH

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1 October 1995

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21 October 2019

The EMBO Journal

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21 October 2019

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21 October 2019

4994-5005

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21 October 2019

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21 October 2019

p53-mediated cell death: relationship to cell cycle control

1 reference

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24 September 2017

Cell cycle analysis of p53-induced cell death in murine erythroleukemia cells

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24 September 2017

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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24 September 2017

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

1 reference

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24 September 2017

WAF1, a potential mediator of p53 tumor suppression

1 reference

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24 September 2017

Epstein-Barr virus nuclear antigen EBNA3C/6 expression maintains the level of latent membrane protein 1 in G1-arrested cells

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24 September 2017

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo

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24 September 2017

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

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24 September 2017

Alterations of the p53 gene in Epstein-Barr virus-associated immunodeficiency-related lymphomas.

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24 September 2017

Apoptosis in cancer therapy: crossing the threshold

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24 September 2017

Cell cycle control and cancer

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24 September 2017

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

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24 September 2017

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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24 September 2017

Apoptosis in the pathogenesis and treatment of disease

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24 September 2017

Mechanisms and genes of cellular suicide

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24 September 2017

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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24 September 2017

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

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24 September 2017

B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2.

1 reference

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24 September 2017

A role for deregulated c-Myc expression in apoptosis of Epstein-Barr virus-immortalized B cells

1 reference

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24 September 2017

A direct effect of activated human p53 on nuclear DNA replication

1 reference

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24 September 2017

Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53

1 reference

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24 September 2017

Induction of latent membrane protein expression in in vitro Epstein-Barr virus-infected leukaemic B lymphocytes by interleukin 4 and antibodies to CD40.

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24 September 2017

Cell death: the significance of apoptosis

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24 September 2017

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

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24 September 2017

Synchronous and sequential activation of latently infected Epstein-Barr virus genomes

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24 September 2017

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

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24 September 2017

Oncogenic forms of p53 inhibit p53-regulated gene expression

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24 September 2017

Social controls on cell survival and cell death

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24 September 2017

Induction of apoptosis in fibroblasts by c-myc protein

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24 September 2017

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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24 September 2017

Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents

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24 September 2017

p53 is frequently mutated in Burkitt's lymphoma cell lines

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25 September 2017

Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form

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25 September 2017

Mediation of c-Myc-induced apoptosis by p53.

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25 September 2017

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

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25 September 2017

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

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25 September 2017

Biological activities of p53 mutants in Burkitt's lymphoma cells

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17 June 2018

Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines.

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17 June 2018

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394603

17 June 2018

Apoptosis in Burkitt lymphoma cells is driven by c-myc.

1 reference

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17 June 2018

Transforming growth factor type beta (TGF beta) inhibits G1 to S transition, but not activation of human B lymphocytes.

1 reference

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17 June 2018

Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis

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17 June 2018

Effect of transforming growth factor-beta 1 and -beta 2 on the proliferation of Burkitt lymphoma and lymphoblastoid cell lines

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17 June 2018

IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: demonstration of a novel role for c-myc

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17 June 2018

p53 mutations in Raji cells: characterization and localization relative to other Burkitt's lymphomas

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17 June 2018

Cell growth effects of Epstein-Barr virus leader protein.

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17 June 2018

Transfection and gene expression in normal and malignant primary B lymphocytes.

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17 June 2018

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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19 August 2018

A nonchromatographic assay for expression of the chloramphenicol acetyltransferase gene in eucaryotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterogeneity of transcriptional activity of mutant p53 proteins and p53 DNA target sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53, guardian of Rb

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Checkpoints of dueling dimers foil death wishes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1995.TB00182.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7588628%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1 reference

Europe PubMed Central

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21 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7588628%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

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