Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease. (Q40773870)

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12 November 2019

title

Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease (English)

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12 November 2019

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W Le

1

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12 November 2019

D Rowe

2

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12 November 2019

W Xie

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12 November 2019

I Ortiz

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12 November 2019

Y He

5

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12 November 2019

S H Appel

6

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12 November 2019

language of work or name

English

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publication date

1 November 2001

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12 November 2019

published in

Journal of Neuroscience

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12 November 2019

volume

21

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12 November 2019

issue

21

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12 November 2019

page(s)

8447-8455

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A rat model of Parkinson's disease induced by Japanese encephalitis virus.

12 November 2019

cites work

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Rate of cell death in parkinsonism indicates active neuropathological process

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Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease.

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Cytokines in inflammatory brain lesions: helpful and harmful

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Oxidized lipoproteins increase reactive oxygen species formation in microglia and astrocyte cell lines

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Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients.

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Therapeutic implications of microglia activation by lipopolysaccharide and reactive oxygen species generation in septic shock and central nervous system pathologies: a review

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Microglia: a sensor for pathological events in the CNS

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Neuronal control of the immune response in the central nervous system: linking brain immunity to neurodegeneration.

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Serum antibodies to L-type calcium channels in patients with amyotrophic lateral sclerosis

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12 December 2020

Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system.

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12 December 2020

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

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12 December 2020

Improving the survival of grafted dopaminergic neurons: a review over current approaches.

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12 December 2020

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

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12 December 2020

A novel N18TG2 x mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin

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FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo

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Covalent crosslinking of neurofilament proteins by oxidized catechols as a potential mechanism of Lewy body formation

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FcR gamma chain deletion results in pleiotrophic effector cell defects

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Cell death induced by beta-amyloid 1-40 in MES 23.5 hybrid clone: the role of nitric oxide and NMDA-gated channel activation leading to apoptosis

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12 December 2020

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

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12 December 2020

Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: an HPLC and ESR study

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Lewy bodies in Parkinson's disease are recognized by antibodies to complement proteins

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Low density lipoprotein uptake by macrophages in multiple sclerosis plaques: implications for pathogenesis.

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12 December 2020

Nigral damage and dopaminergic hypofunction in mesencephalon-immunized guinea pigs

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12 December 2020

Excitotoxicity and nitric oxide in Parkinson's disease pathogenesis

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12 December 2020

Specific infection and destruction of dopaminergic neurons in the substantia nigra by Theiler's virus

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12 December 2020

Antibody-induced generation of reactive oxygen radicals by brain macrophages in canine distemper encephalitis: a mechanism for bystander demyelination

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12 December 2020

Role of protein kinase C in microglia-induced neurotoxicity in mesencephalic cultures.

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12 December 2020

FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells.

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12 December 2020

Antibodies from patients with Parkinson's disease react with protein modified by dopamine oxidation.

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12 December 2020

Effects of cerebrospinal fluid from patients with Parkinson disease on dopaminergic cells.

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12 December 2020

Altered glial function causes neuronal death and increases neuronal susceptibility to 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced toxicity in astrocytic/ventral mesencephalic co-cultures

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12 December 2020

Inhibition of tyrosine hydroxylase expression within the substantia nigra of mice infected with canine distemper virus

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12 December 2020

beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease.

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12 December 2020

Experimental autoimmune nigral damage in guinea pigs

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12 December 2020

Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons

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12 December 2020

Activated microglia mediate neuronal cell injury via a nitric oxide mechanism

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12 December 2020

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

1 reference

12 December 2020

10.1523/JNEUROSCI.21-21-08447.2001

Identifiers

DOI

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12 November 2019

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12 November 2019

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