Differential activation of nuclear factor-kappaB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly (Q40739271)

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scientific article published on March 2002

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English	Differential activation of nuclear factor-kappaB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly	scientific article published on March 2002

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scholarly article

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Europe PubMed Central

PubMed publication ID

23 September 2017

Differential activation of nuclear factor-kappaB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly (English)

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Europe PubMed Central

PubMed publication ID

23 September 2017

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David J MacEwan

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David J MacEwan

7

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Peter Vandenabeele

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Peter Vandenabeele

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author name string

Shona M McFarlane

1

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Europe PubMed Central

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23 September 2017

Ghazaleh Pashmi

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Europe PubMed Central

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23 September 2017

Michelle C Connell

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Europe PubMed Central

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23 September 2017

Alison F Littlejohn

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Europe PubMed Central

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23 September 2017

Steven J Tucker

5

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Europe PubMed Central

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23 September 2017

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publication date

1 March 2002

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Europe PubMed Central

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23 September 2017

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Europe PubMed Central

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23 September 2017

515

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23 September 2017

1-3

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23 September 2017

119-126

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23 September 2017

Two tumour necrosis factor receptors: structure and function.

1 reference

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The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

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The p70 tumor necrosis factor receptor mediates cytotoxicity

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Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor

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Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

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Stress-activated protein kinases: activation, regulation and function.

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The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation

1 reference

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21 January 2018

Hormonal regulation of the NF-kappaB signaling pathway

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Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

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Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements

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The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

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21 January 2018

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

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21 January 2018

Identification and characterization of an IkappaB kinase

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21 January 2018

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

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21 January 2018

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

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21 January 2018

Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB.

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21 January 2018

Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I

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21 January 2018

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

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21 January 2018

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

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Regulated commitment of TNF receptor signaling: a molecular switch for death or activation.

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Non-specific effects of methyl ketone peptide inhibitors of caspases

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A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

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21 January 2018

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

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Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

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The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

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21 January 2018

Tumor necrosis factor-alpha mediates both apoptotic cell death and cell proliferation in a human hematopoietic cell line dependent on mitotic activity and receptor subtype expression

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21 January 2018

Modulated kinase activities in cells undergoing tumour necrosis factor-induced apoptotic cell death

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21 January 2018

Evidence for exclusive role in signalling of tumour necrosis factor p55 receptor and a potentiating function of p75 receptor on human endothelial cells

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21 January 2018

Generation and Biological Characterization of Membrane-bound, Uncleavable Murine Tumor Necrosis Factor

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21 January 2018

Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins

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21 January 2018

Tumor necrosis factor receptor (TNFR)-associated factor 2A (TRAF2A), a TRAF2 splice variant with an extended RING finger domain that inhibits TNFR2-mediated NF-kappaB activation

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Tumor necrosis factor (TNF) receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1

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Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kinetics

1 reference

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7 January 2021

Identifiers

10.1016/S0014-5793(02)02450-X

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

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