Mutation of the GABAA receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement. (Q40738113)

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9 December 2019

title

Mutation of the GABAA receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement (English)

1 reference

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9 December 2019

main subject

transmembrane protein

0 references

author

Shahid H Zaman

2

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9 December 2019

author name string

L John Greenfield

1

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9 December 2019

Margaret L Sutherland

3

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9 December 2019

Sarah C R Lummis

4

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9 December 2019

María-Isabel Niemeyer

5

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9 December 2019

Eric A Barnard

6

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9 December 2019

Robert L Macdonald

7

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9 December 2019

publication date

1 March 2002

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9 December 2019

number of pages

20

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based on heuristic

inferred from page(s)

published in

Neuropharmacology

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9 December 2019

volume

42

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9 December 2019

issue

4

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9 December 2019

page(s)

502-521

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Identification of acetylcholine receptor channel-lining residues in the M1 segment of the alpha-subunit

9 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Assembly of GABAA receptor subunits: alpha 1 beta 1 and alpha 1 beta 1 gamma 2S subunits produce unique ion channels with dissimilar single- channel properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Assembly of GABAA receptor subunits: analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

theta, a novel gamma-aminobutyric acid type A receptor subunit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Green fluorescent protein as a marker for gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Channel opening locks agonist onto the GABAC receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

High-efficiency transformation of mammalian cells by plasmid DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Energy profiles in the acetylcholine receptor (AChR) channel. The MII-helix model and the role of the remaining helices

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Whole-cell and single-channel alpha1 beta1 gamma2S GABAA receptor currents elicited by a "multipuffer" drug application device

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Expression of functional GABAA receptors in transfected L929 cells isolated by immunomagnetic bead separation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Stable expression of mammalian type A gamma-aminobutyric acid receptors in mouse cells: demonstration of functional assembly of benzodiazepine-responsive sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Statistical methods for model discrimination. Applications to gating kinetics and permeation of the acetylcholine receptor channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Evidence for a common binding cavity for three general anesthetics within the GABAA receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Desensitized states prolong GABAA channel responses to brief agonist pulses.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Rapid and efficient site-specific mutagenesis without phenotypic selection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Direct sequencing of lambda DNA from crude lysates using an improved linear amplification technique

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Influence of proline residues on protein conformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Sampling, log binning, fitting, and plotting durations of open and shut intervals from single channels and the effects of noise

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Quaternary structure of the native GABAA receptor determined by electron microscopic image analysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Neurosteroids act on recombinant human GABAA receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Benzodiazepine and beta-carboline regulation of single GABAA receptor channels of mouse spinal neurones in culture.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

The effect of subunit composition of rat brain GABAA receptors on channel function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Data transformations for improved display and fitting of single-channel dwell time histograms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Functional domains of GABAA receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Effects of glycine and GABA on isolated bipolar cells of the mouse retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Intraburst kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Acetylcholine receptor channel imaged in the open state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Functional properties of recombinant rat GABAA receptors depend upon subunit composition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Mutation in the M1 domain of the acetylcholine receptor alpha subunit decreases the rate of agonist dissociation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Alpha subunits influence Zn block of gamma 2 containing GABAA receptor currents

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Effects of subunit types of the recombinant GABAA receptor on the response to a neurosteroid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

Delta subunit inhibits neurosteroid modulation of GABAA receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2801%2900196-4

10.1016/S0028-3908(01)00196-4

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11955521%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

1 reference