Distinct phosphorylation events regulate p130- and p107-mediated repression of E2F-4. (Q40732655)

23 September 2017

Distinct phosphorylation events regulate p130- and p107-mediated repression of E2F-4. (English)

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23 September 2017

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4

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23 September 2017

5

Jiri Bartek

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23 September 2017

Klaus Hansen

2

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author name string

Thomas Farkas

series ordinal

1

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PubMed ID

12006580

23 September 2017

Karin Holm

series ordinal

3

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PubMed ID

12006580

23 September 2017

language of work or name

English

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publication date

2 May 2002

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Journal of Biological Chemistry

23 September 2017

12

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based on heuristic

inferred from page(s)

published in

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23 September 2017

277

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23 September 2017

30

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23 September 2017

26741-26752

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Retinoblastoma protein in growth suppression and death protection

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

p107 and p130: versatile proteins with interesting pockets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

The retinoblastoma gene family in differentiation and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Retinoblastoma protein partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

The retinoblastoma protein pathway in cell cycle control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Regulation of cell proliferation by the E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Phosphorylation-dependent and -independent functions of p130 cooperate to evoke a sustained G1 block.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Phosphorylation of the retinoblastoma-related protein p130 in growth-arrested cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Hyperphosphorylated p107 and p130 bind to T-antigen: identification of a critical regulatory sequence present in RB but not in p107/p130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Intramolecular repression of mouse heat shock factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Control of pRB phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Disruption of retinoblastoma protein function by coexpression of its C pocket fragment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Accumulation of cyclin E is not a prerequisite for passage through the restriction point

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Establishment of irreversible growth arrest in myogenic differentiation requires the RB LXCXE-binding function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Role of the LXCXE binding site in Rb function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

pRB phosphorylation mutants reveal role of pRB in regulating S phase completion by a mechanism independent of E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Target gene specificity of E2F and pocket protein family members in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Nuclear organization of DNA replication in primary mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

The Rb/E2F pathway and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

Pathways governing G1/S transition and their response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200381200

21 January 2018

Identifiers

DOI

10.1074/JBC.M200381200

1 reference

23 September 2017

1 reference

PubMed ID

12006580