Agonists activate Gi1 alpha or Gi2 alpha fused to the human mu opioid receptor differently (Q40724494)

23 September 2017

Agonists activate Gi1 alpha or Gi2 alpha fused to the human mu opioid receptor differently (English)

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23 September 2017

Dominique Massotte

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author name string

Karl Brillet

series ordinal

2

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23 September 2017

Brigitte Kieffer

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3

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23 September 2017

Graeme Milligan

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4

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23 September 2017

language of work or name

English

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publication date

1 June 2002

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Journal of Neurochemistry

23 September 2017

11

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inferred from page(s)

published in

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23 September 2017

81

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23 September 2017

6

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23 September 2017

1372-1382

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Hydrophobicity of residue351 of the G protein Gi1 alpha determines the extent of activation by the alpha 2A-adrenoceptor.

23 September 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Agonist occupation of an alpha2A-adrenoreceptor-Gi1alpha fusion protein results in activation of both receptor-linked and endogenous Gi proteins. Comparisons of their contributions to GTPase activity and signal transduction and analysis of receptor-

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Immunoprecipitation of high-affinity, guanine nucleotide-sensitive, solubilized mu-opioid receptors from rat brain: coimmunoprecipitation of the G proteins G(alpha o), G(alpha i1), and G(alpha i3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Activation of type II adenylyl cyclase by the cloned mu-opioid receptor: coupling to multiple G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Activation of mitogen-activated protein kinase by membrane-targeted Raf chimeras is independent of raft localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Opioid receptor signalling mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Antagonists of excitatory opioid receptor functions enhance morphine's analgesic potency and attenuate opioid tolerance/dependence liability

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Immunoprecipitation of opioid receptor-Go-protein complexes using specific GTP-binding-protein antisera

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Distinct roles for Galpha(i)2 and Gbetagamma in signaling to DNA synthesis and Galpha(i)3 in cellular transformation by dopamine D2S receptor activation in BALB/c 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Reporter-gene systems for the study of G-protein-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Two active molecular phenotypes of the tachykinin NK1 receptor revealed by G-protein fusions and mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

G(i1) and G(oA) differentially determine kinetic efficacies of agonists for kappa-opioid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

mu and delta opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

The role of members of the pertussis toxin-sensitive family of G proteins in coupling receptors to the activation of the G protein-gated inwardly rectifying potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Delta-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Insights into ligand pharmacology using receptor-G-protein fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

A mitogen-activated protein kinase pathway is required for mu-opioid receptor desensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Properties of a kappa-opioid receptor expressed in CHO cells: interaction with multiple G-proteins is not specific for any individual G alpha subunit and is similar to that of other opioid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Agonists determine the pattern of G-protein activation in mu-opioid receptor-mediated supraspinal analgesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Examining the efficiency of receptor/G-protein coupling with a cleavable beta2-adrenoceptor-gsalpha fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Fusion of beta 2-adrenergic receptor to G alpha s in mammalian cells: identification of a specific signal transduction species not characteristic of constitutive activation or precoupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Coupling efficacy and selectivity of the human mu-opioid receptor expressed as receptor-Galpha fusion proteins in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Coordinated agonist regulation of receptor and G protein palmitoylation and functional rescue of palmitoylation-deficient mutants of the G protein G11alpha following fusion to the alpha1b-adrenoreceptor: palmitoylation of G11alpha is not required fo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Opioid receptor endocytosis and activation of MAP kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Coupling of the muscarinic m2 receptor to G protein-activated K(+) channels via Galpha(z) and a receptor-Galpha(z) fusion protein. Fusion between the receptor and Galpha(z) eliminates catalytic (collision) coupling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Quantitative analysis of formyl peptide receptor coupling to g(i)alpha(1), g(i)alpha(2), and g(i)alpha(3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Rescue of functional interactions between the alpha2A-adrenoreceptor and acylation-resistant forms of Gi1alpha by expressing the proteins from chimeric open reading frames.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Interactions of the alpha2A-adrenoceptor with multiple Gi-family G-proteins: studies with pertussis toxin-resistant G-protein mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

The rat D4 dopamine receptor couples to cone transducin (Galphat2) to inhibit forskolin-stimulated cAMP accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

10.1046/J.1471-4159.2002.00946.X

21 January 2018

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DOI

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23 September 2017

1 reference