Antagonists of excitatory amino acids and endogenous opioid peptides in the treatment of experimental central nervous system injury (Q40710288)

23 September 2017

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title

Antagonists of excitatory amino acids and endogenous opioid peptides in the treatment of experimental central nervous system injury (English)

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23 September 2017

Gentile NT

1

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PubMed ID

8099259

23 September 2017

McIntosh TK

series ordinal

2

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PubMed ID

8099259

23 September 2017

language of work or name

English

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publication date

1 June 1993

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Annals of Emergency Medicine

23 September 2017

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23 September 2017

22

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23 September 2017

6

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23 September 2017

1028-1034

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Glutamate and the pathophysiology of hypoxic--ischemic brain damage

23 September 2017

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Anti-parkinsonian agents are phencyclidine agonists and N-methyl-aspartate antagonists

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Convulsant action of intracerebroventricularly administered l-kynurenine sulphate, quinolinic acid and other derivatives of succinic acid, and effects of amino acids: structure-activity relationships

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Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors

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Calcium, network activity, and the role of NMDA channels in synaptic plasticity in vitro

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A quantitative description of NMDA receptor-channel kinetic behavior

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Neurobiology. Taking apart NMDA receptors

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Ionic dependence of glutamate neurotoxicity

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Mitochondria and other calcium buffers of squid axon studied in situ

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Calcium-activated neutral protease in the peripheral nerve, which requires microM order Ca2+, and its effect on the neurofilament triplet

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7 January 2021

The role of excitatory amino acids and NMDA receptors in traumatic brain injury

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7 January 2021

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil.

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MK-801 is neuroprotective in gerbils when administered during the post-ischaemic period

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7 January 2021

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

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Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist.

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7 January 2021

Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury

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Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats.

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Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cord.

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Excitatory amino acid receptor subtype binding following traumatic brain injury.

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NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

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Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury.

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Pretreatment with phencyclidine, an N-methyl-D-aspartate antagonist, attenuates long-term behavioral deficits in the rat produced by traumatic brain injury

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Combined pretrauma scopolamine and phencyclidine attenuate posttraumatic increased sensitivity to delayed secondary ischemia

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The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate

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7 January 2021

Protective effect of MK801 in experimental brain injury

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Effect of noncompetitive blockade of N-methyl-D-aspartate receptors on the neurochemical sequelae of experimental brain injury

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7 January 2021

Decrease in total and free magnesium concentration following traumatic brain injury in rats

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Alterations in tissue Mg++, Na+ and spinal cord edema following impact trauma in rats

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Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons.

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Indole-2-carboxylic acid: a competitive antagonist of potentiation by glycine at the NMDA receptor

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Endogenous opioid immunoreactivity in rat spinal cord following traumatic injury

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Effect of naloxone on posttraumatic ischemia in experimental spinal contusion

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7 January 2021

Alterations in regional concentrations of endogenous opioids following traumatic brain injury in the cat.

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7 January 2021

Opiate antagonist improves neurologic recovery after spinal injury

1 reference

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Effect of naloxone on functional recovery after experimental spinal cord injury in the rat

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Treatment of experimental spinal cord injury with TRH, naloxone, and dexamethasone

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Naloxone and experimental spinal cord injury: effect of varying dose and intensity of injury

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Blocking weight-induced spinal cord injury in rats: effects of TRH or naloxone on motor function recovery and spinal cord blood flow

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A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

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Effects of naloxone on systemic and cerebral responses to experimental concussive brain injury in cats

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Possible protective effect of endogenous opioids in traumatic brain injury

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Neuropeptides and central nervous system injury. Clinical implications

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Opioid and nonopioid mechanisms may contribute to dynorphin's pathophysiological actions in spinal cord injury

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Opiate antagonist nalmefene improves intracellular free Mg2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats.

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7 January 2021

Beneficial effects of the kappa opioid receptor agonist U-50488H in experimental acute brain and spinal cord injury

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The kappa opioid-related anticonvulsants U-50488H and U-54494A attenuate N-methyl-D-aspartate induced brain injury in the neonatal rat

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The interaction between kappa-opioid agonist, U-50, 488H, and kainic acid: behavioral and histological assessments

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Thyrotropin-releasing hormone in experimental spinal injury: dose response and late treatment

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Neuropeptides in spinal cord injury: comparative experimental models

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TRH analog YM-14673 improves outcome following traumatic brain and spinal cord injury in rats: dose-response studies

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7 January 2021

Treatment with the thyrotropin-releasing hormone analog CG3703 restores magnesium homeostasis following traumatic brain injury in rats

1 reference

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Magnesium deprivation reproduces the coordinate effects of serum removal or cortisol addition on transport and metabolism in chick embryo fibroblasts

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7 January 2021

31P NMR characterization of graded traumatic brain injury in rats

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Effects of traumatic brain injury on cerebral high-energy phosphates and pH: a 31P magnetic resonance spectroscopy study

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Opiate receptor: multiple effects of metal ions.

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7 January 2021

Magnesium gates glutamate-activated channels in mouse central neurones

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7 January 2021

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

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7 January 2021

Magnesium deficiency exacerbates and pretreatment improves outcome following traumatic brain injury in rats: 31P magnetic resonance spectroscopy and behavioral studies

1 reference

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7 January 2021

Magnesium protects against neurological deficit after brain injury

1 reference

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7 January 2021

10.1016/S0196-0644(05)82746-5

Identifiers

DOI

1 reference

23 September 2017

1 reference

PubMed ID

8099259