Quaternary organization of the goodpasture autoantigen, the alpha 3(IV) collagen chain. Sequestration of two cryptic autoepitopes by intrapromoter interactions with the alpha4 and alpha5 NC1 domains. (Q40708995)

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scientific article published on 21 August 2002

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English	Quaternary organization of the goodpasture autoantigen, the alpha 3(IV) collagen chain. Sequestration of two cryptic autoepitopes by intrapromoter interactions with the alpha4 and alpha5 NC1 domains.	scientific article published on 21 August 2002

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scholarly article

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12 November 2019

Quaternary organization of the goodpasture autoantigen, the alpha 3(IV) collagen chain. Sequestration of two cryptic autoepitopes by intrapromoter interactions with the alpha4 and alpha5 NC1 domains (English)

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12 November 2019

Dorin-Bogdan Borza

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12 November 2019

Billy G. Hudson

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12 November 2019

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Olga Bondar

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12 November 2019

Parvin Todd

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12 November 2019

Munirathinam Sundaramoorthy

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12 November 2019

Yoshikazu Sado

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12 November 2019

Yoshifumi Ninomiya

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12 November 2019

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21 August 2002

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12 November 2019

Journal of Biological Chemistry

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12 November 2019

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12 November 2019

40075-40083

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12 November 2019

42

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12 November 2019

The goodpasture autoantigen. Mapping the major conformational epitope(s) of alpha3(IV) collagen to residues 17-31 and 127-141 of the NC1 domain.

1 reference

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The goodpasture autoantigen. Identification of multiple cryptic epitopes on the NC1 domain of the alpha3(IV) collagen chain.

1 reference

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Crystal structure of NC1 domains. Structural basis for type IV collagen assembly in basement membranes

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The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link

1 reference

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21 January 2018

The Goodpasture autoantigen. Structural delineation of two immunologically privileged epitopes on alpha3(IV) chain of type IV collagen.

1 reference

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Induction of anti-GBM nephritis in rats by recombinant alpha 3(IV)NC1 and alpha 4(IV)NC1 of type IV collagen

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Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies

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Reductive cleavage and reformation of the interchain and intrachain disulfide bonds in the globular hexameric domain NC1 involved in network assembly of basement membrane collagen (type IV)

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Unusual dissociative behavior of the noncollagenous domain (hexamer) of basement membrane collagen during electrophoresis and chromatofocusing

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Comparative analysis of the noncollagenous NC1 domain of type IV collagen: identification of structural features important for assembly, function, and pathogenesis

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Glomerular expression of type IV collagen chains in normal and X-linked Alport syndrome kidneys

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Comparative distribution of the alpha 1(IV), alpha 5(IV), and alpha 6(IV) collagen chains in normal human adult and fetal tissues and in kidneys from X-linked Alport syndrome patients

1 reference

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21 January 2018

Goodpasture disease. Characterization of a single conformational epitope as the target of pathogenic autoantibodies.

1 reference

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A network model for the organization of type IV collagen molecules in basement membranes

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Self-assembly of basement membrane collagen

1 reference

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Glomerular basement membrane. Identification of a novel disulfide-cross-linked network of alpha3, alpha4, and alpha5 chains of type IV collagen and its implications for the pathogenesis of Alport syndrome

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Type IV collagen of the glomerular basement membrane. Evidence that the chain specificity of network assembly is encoded by the noncollagenous NC1 domains

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Hydrophobic amino acid residues are critical for the immunodominant epitope of the Goodpasture autoantigen. A molecular basis for the cryptic nature of the epitope

1 reference

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21 January 2018

The NC1 domain of collagen IV encodes a novel network composed of the alpha 1, alpha 2, alpha 5, and alpha 6 chains in smooth muscle basement membranes

1 reference

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21 January 2018

Establishment by the rat lymph node method of epitope-defined monoclonal antibodies recognizing the six different alpha chains of human type IV collagen

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21 January 2018

Differential expression of type IV collagen isoforms, alpha5(IV) and alpha6(IV) chains, in basement membranes surrounding smooth muscle cells

1 reference

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Folding of collagen IV

1 reference

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Absence of alpha 6(IV) collagen in kidney and skin of X-linked Alport syndrome patients

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Immunohistologic findings in Alport syndrome.

1 reference

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Autosomal recessive Alport syndrome: Immunohistochemical study of type IV collagen chain distribution

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Fibrillary glomerulonephritis in siblings

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