Epstein-Barr virus-associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2. (Q40705440)

22 September 2017

Epstein-Barr virus-associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2. (English)

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22 September 2017

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22 September 2017

Alan Bernard Rickinson

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3

object named as

Alan Rickinson

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22 September 2017

Gemma Kelly

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22 September 2017

language of work or name

English

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publication date

3 September 2002

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22 September 2017

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1098-1104

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10

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describes a project that uses

22 September 2017

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https://scigraph.springernature.com/pub.10.1038/nm758

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cites work

Restricted Epstein-Barr virus protein expression in Burkitt lymphoma is due to a different Epstein-Barr nuclear antigen 1 transcriptional initiation site

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Exclusive expression of Epstein-Barr virus nuclear antigen 1 in Burkitt lymphoma arises from a third promoter, distinct from the promoters used in latently infected lymphocytes

21 January 2018

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Redefining the Epstein-Barr virus-encoded nuclear antigen EBNA-1 gene promoter and transcription initiation site in group I Burkitt lymphoma cell lines

21 January 2018

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Expression of Epstein-Barr virus transformation-associated genes in tissues of patients with EBV lymphoproliferative disease

21 January 2018

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Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytes

21 January 2018

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Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection

21 January 2018

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Epstein-Barr virus-encoded nuclear antigen 2 activates the viral latent membrane protein promoter by modulating the activity of a negative regulatory element

21 January 2018

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The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell

21 January 2018

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Role of cytotoxic T lymphocytes in Epstein-Barr virus-associated diseases

21 January 2018

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Antagonistic effects of c-myc and Epstein-Barr virus latent genes on the phenotype of human B cells

21 January 2018

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Restoration of endogenous antigen processing in Burkitt's lymphoma cells by Epstein-Barr virus latent membrane protein-1: coordinate up-regulation of peptide transporters and HLA-class I antigen expression

21 January 2018

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Endoplasmic reticulum signal sequence facilitated transport of peptide epitopes restores immunogenicity of an antigen processing defective tumour cell line.

21 January 2018

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Sequence and transcription of Raji Epstein-Barr virus DNA spanning the B95-8 deletion region

21 January 2018

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Determining the role of the Epstein-Barr virus Cp EBNA2-dependent enhancer during the establishment of latency by using mutant and wild-type viruses recovered from cottontop marmoset lymphoblastoid cell lines

21 January 2018

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Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas

21 January 2018

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Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

21 January 2018

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Epstein-barr virus regulates c-MYC, apoptosis, and tumorigenicity in Burkitt lymphoma

21 January 2018

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c-myc activation renders proliferation of Epstein-Barr virus (EBV)-transformed cells independent of EBV nuclear antigen 2 and latent membrane protein 1.

21 January 2018

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c-myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells.

21 January 2018

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MYC overexpression imposes a nonimmunogenic phenotype on Epstein-Barr virus-infected B cells

21 January 2018

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Burkitt lymphoma in the mouse.

21 January 2018

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Endemic Burkitt's lymphoma: phenotypic analysis of tumor biopsy cells and of derived tumor cell lines

21 January 2018

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Rapid effector function in CD8+ memory T cells

21 January 2018

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Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cells

21 January 2018

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7 January 2021

Transcription start sites downstream of the Epstein-Barr virus (EBV) Fp promoter in early-passage Burkitt lymphoma cells define a fourth promoter for expression of the EBV EBNA-1 protein

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7 January 2021

Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein.

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7 January 2021

Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1.

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7 January 2021

Epstein-Barr virus nuclear antigen 2 activates transcription of the terminal protein gene

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7 January 2021

Monoclonal and polyclonal antibodies against Epstein-Barr virus nuclear antigen 5 (EBNA-5) detect multiple protein species in Burkitt's lymphoma and lymphoblastoid cell lines

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7 January 2021

Non-immortalizing P3J-HR-1 Epstein-Barr virus: a deletion mutant of its transforming parent, Jijoye

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7 January 2021

The EB virus genome in Daudi Burkitt's lymphoma cells has a deletion similar to that observed in a non-transforming strain (P3HR-1) of the virus.

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7 January 2021

Mutations in the first exon are associated with altered transcription of c-myc in Burkitt lymphoma

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7 January 2021

Epstein-Barr virus contributes to the malignant phenotype and to apoptosis resistance in Burkitt's lymphoma cell line Akata.

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7 January 2021

Identifiers

DOI

10.1038/NM758

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22 September 2017

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