Desensitization mechanism of GABA receptors revealed by single oocyte binding and receptor function. (Q40704823)

PubMed publication ID

12223551

22 September 2017

title

Desensitization mechanism of GABA receptors revealed by single oocyte binding and receptor function (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758118&resulttype=core&format=json

12 May 2020

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Yongchang Chang

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758118&resulttype=core&format=json

12 May 2020

Emmanuel Ghansah

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758118&resulttype=core&format=json

12 May 2020

Yonghui Chen

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758118&resulttype=core&format=json

12 May 2020

Jiawei Ye

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758118&resulttype=core&format=json

12 May 2020

David S Weiss

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758118&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 September 2002

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PubMed publication ID

12223551

22 September 2017

number of pages

9

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inferred from page(s)

published in

Journal of Neuroscience

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12 May 2020

volume

22

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12 May 2020

issue

18

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12 May 2020

page(s)

7982-7990

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758118&resulttype=core&format=json

Channel opening locks agonist onto the GABAC receptor.

12 May 2020

cites work

1 reference

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A study of the desensitization produced by acetylcholine at the motor end-plate

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Upregulation of surface alpha4beta2 nicotinic receptors is initiated by receptor desensitization after chronic exposure to nicotine.

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Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system.

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Kinetics of binding of [3H]acetylcholine to Torpedo postsynaptic membranes: association and dissociation rate constants by rapid mixing and ultrafiltration

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

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Kinetics of agonist-mediated transitions in state of the cholinergic receptor.

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A Structural Determinant of Desensitization and Allosteric Regulation by Pentobarbitone of the GABA A Receptor

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Ligand-induced conformation changes in Torpedo californica membrane-bound acetylcholine receptor

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Regulation of binding properties of the nicotinic receptor protein by cholinergic ligands in membrane fragments from Torpedo marmorata

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GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital.

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12 December 2020

Rapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine receptor rich membranes from Torpedo marmorata.

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12 December 2020

Functional consequences of agonist-mediated state transitions in the cholinergic receptor. Studies in cultured muscle cells

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Biochemical pharmacology of the gamma-aminobutyric acid receptor/ionophore protein

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12 December 2020

Allosteric activation mechanism of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid type A receptor revealed by mutation of the conserved M2 leucine

1 reference

12 December 2020

Allosteric receptors after 30 years

1 reference

12 December 2020

Neurosteroid prolongs GABAA channel deactivation by altering kinetics of desensitized states

1 reference

12 December 2020

Desensitized states prolong GABAA channel responses to brief agonist pulses.

1 reference

12 December 2020

Distinct deactivation and desensitization kinetics of recombinant GABAA receptors

1 reference

12 December 2020

gamma-Aminobutyric acid receptor binding in mammalian brain. Heterogeneity of binding sites

1 reference

12 December 2020

Homomeric rho 1 GABA channels: activation properties and domains.

1 reference

12 December 2020

On the mechanism of desensitization at cholinergic receptors

1 reference

12 December 2020

Conformations of Torpedo acetylcholine receptor associated with ion transport and desensitization

1 reference

12 December 2020

Slow desensitization regulates the availability of synaptic GABA(A) receptors

1 reference

12 December 2020

Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.

1 reference

12 December 2020

Allosteric proteins after thirty years: the binding and state functions of the neuronal alpha 7 nicotinic acetylcholine receptors

1 reference

12 December 2020

10.1523/JNEUROSCI.22-18-07982.2002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758118&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758118&resulttype=core&format=json

12 May 2020

PubMed publication ID

12223551

1 reference