Total synthesis of oxidized welwitindolinones and (-)-N-methylwelwitindolinone C isonitrile (Q40685847)

22 September 2017

Total synthesis of oxidized welwitindolinones and (-)-N-methylwelwitindolinone C isonitrile (English)

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22 September 2017

4

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author name string

Kyle W Quasdorf

1

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22 September 2017

Alexander D Huters

2

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22 September 2017

Michael W Lodewyk

3

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22 September 2017

Neil K Garg

5

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22 September 2017

language of work or name

English

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publication date

11 January 2012

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Journal of the American Chemical Society

22 September 2017

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22 September 2017

134

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22 September 2017

1396-1399

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22 September 2017

3

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Lessons Learned while Traversing the Welwitindolinone Alkaloids Obstacle Course

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Computational prediction of 1H and 13C chemical shifts: a useful tool for natural product, mechanistic, and synthetic organic chemistry

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Total synthesis of (-)-N-methylwelwitindolinone C isothiocyanate

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Directed oxidative cyclizations to C2- or C4-positions of indole: efficient construction of the bicyclo[4.3.1]decane core of welwitindolinones.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Total synthesis of N-methylwelwitindolinone D isonitrile

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Addressing the stereochemistry of complex organic molecules by density functional theory-NMR: vannusal B in retrospective

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Approaches to N-methylwelwitindolinone C isothiocyanate: facile synthesis of the tetracyclic core

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Synthesis of the bicyclic welwitindolinone core via an alkylation/cyclization cascade reaction

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Enantiospecific total synthesis of the hapalindoles, fischerindoles, and welwitindolinones via a redox economic approach

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Welwistatin support studies: expansion and limitation of aryllead(IV) coupling reactions

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

An approach to the total synthesis of welwistatin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Total synthesis of norzoanthamine.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

A stereoselective synthesis of (-)-tetrodotoxin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Microtubule effects of welwistatin, a cyanobacterial indolinone that circumvents multiple drug resistance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Welwitindolinone analogues that reverse P-glycoprotein-mediated multiple drug resistance.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Studies in catalytic C-H amination involving nitrene C-H insertion

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Welwitindolinone C synthetic studies. Construction of the welwitindolinone carbon skeleton via a transannular nitrone cycloaddition

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Calculating accurate proton chemical shifts of organic molecules with density functional methods and modest basis sets.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Aziridinomitosenes by anionic cyclization: deuterium as a removable blocking group

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Structure of the lycorinine alkaloid nobilisitine A.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Prediction of the structure of nobilisitine a using computed NMR chemical shifts

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Concise and very efficient synthesis of the N-methylwelwistatin tetracyclic core based on an anionic domino process

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Access to a welwitindolinone core using sequential cycloadditions

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Bridgehead enolates and bridgehead alkenes in a welwistatin model series

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Total synthesis of (+/-)-welwitindolinone a isonitrile

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Enantioselective total syntheses of welwitindolinone A and fischerindoles I and G.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Aryllead(IV) reagents in synthesis: formation of the C11 quaternary center of N-methylwelwitindolinone C isothiocyanate.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

A Rh-Catalyzed C-H Insertion Reaction for the Oxidative Conversion of Carbamates to Oxazolidinones We thank Professors Brauman, Stack, Trost, and Wender for many helpful discussions. C.G.E. is the recipient of an NSF Predoctoral Fellowship. J.D.B. g

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266994

Oxidized welwitindolinones from terrestrial fischerella spp

19 August 2018

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12 December 2020

An Expedient Construction of Seven-Membered Rings Adjoining Aromatic Systems

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12 December 2020

A silver-catalyzed intramolecular amidation of saturated C--h bonds

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12 December 2020

Rapid synthesis of the N-methylwelwitindolinone skeleton

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12 December 2020

Rapid access to the Welwitindolinone alkaloid skeleton by cyclization of indolecarboxaldehyde substituted cyclohexanones

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12 December 2020

Alpha-heteroarylation of esters, lactones, amides, and lactams by nucleophilic aromatic substitution

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12 December 2020

A synthesis of the welwistatin core

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12 December 2020

Silver-catalyzed intermolecular amination of C--H groups

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12 December 2020

Palladium-catalyzed alpha-arylation of oxindoles

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12 December 2020

Catalytic asymmetric hydroxylation of oxindoles by molecular oxygen using a phase-transfer catalyst

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12 December 2020

Concise synthesis of the bicyclic scaffold of N-methylwelwitindolinone C isothiocyanate via an indolyne cyclization

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12 December 2020

Assigning stereochemistry to single diastereoisomers by GIAO NMR calculation: the DP4 probability

1 reference

12 December 2020

Stereocontrolled synthesis of 20,21-dihydro N-methylwelwitindolinone B isothiocyanate

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12 December 2020

A Rh-Catalyzed C-H Insertion Reaction for the Oxidative Conversion of Carbamates to Oxazolidinones

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12 December 2020

Identifiers

DOI

10.1021/JA210837B

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22 September 2017

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22 September 2017

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