Interaction of Hsp90 with the nascent form of the mutant epidermal growth factor receptor EGFRvIII. (Q40684830)

22 September 2017

Interaction of Hsp90 with the nascent form of the mutant epidermal growth factor receptor EGFRvIII. (English)

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22 September 2017

Sylvie J Lavictoire

1

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22 September 2017

Doris A E Parolin

2

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22 September 2017

Alex C Klimowicz

3

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22 September 2017

John F Kelly

4

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22 September 2017

Ian A J Lorimer

5

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22 September 2017

language of work or name

English

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publication date

5 December 2002

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

5292-5299

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22 September 2017

7

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Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

22 September 2017

1 reference

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A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor receptor gene in human brain tumors

21 January 2018

1 reference

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Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

21 January 2018

1 reference

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Structural alterations of the epidermal growth factor receptor gene in human gliomas

21 January 2018

1 reference

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Expression of activated epidermal growth factor receptors, Ras-guanosine triphosphate, and mitogen-activated protein kinase in human glioblastoma multiforme specimens

21 January 2018

1 reference

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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

21 January 2018

1 reference

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A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

21 January 2018

1 reference

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The INK4a/ARF network in tumour suppression

21 January 2018

1 reference

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Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209494200

The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy

21 January 2018

1 reference

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Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implications

21 January 2018

1 reference

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Mutant epidermal growth factor receptors as targets for cancer therapy

21 January 2018

1 reference

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The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

21 January 2018

1 reference

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Specific targeting of a mutant, activated FGF receptor found in glioblastoma using a monoclonal antibody

21 January 2018

1 reference

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Activation of extracellular-regulated kinases by normal and mutant EGF receptors

21 January 2018

1 reference

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Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: targeting with a single chain antibody variable domain isolated by phage display

21 January 2018

1 reference

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A transient three-plasmid expression system for the production of high titer retroviral vectors

21 January 2018

1 reference

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Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII

21 January 2018

1 reference

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Targeting retrovirus to cancer cells expressing a mutant EGF receptor by insertion of a single chain antibody variable domain in the envelope glycoprotein receptor binding lobe

21 January 2018

1 reference

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Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides.

21 January 2018

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Steroid receptor interactions with heat shock protein and immunophilin chaperones

21 January 2018

1 reference

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p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site

21 January 2018

1 reference

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Hop modulates Hsp70/Hsp90 interactions in protein folding

21 January 2018

1 reference

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Hop as an adaptor in the heat shock protein 70 (Hsp70) and hsp90 chaperone machinery

21 January 2018

1 reference

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Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity

21 January 2018

1 reference

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Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

21 January 2018

1 reference

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Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209494200

Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway

21 January 2018

1 reference

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Aspartyl beta-hydroxylase: in vitro hydroxylation of a synthetic peptide based on the structure of the first growth factor-like domain of human factor IX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209494200

Hsp90: chaperoning signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209494200

In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone

21 January 2018

1 reference

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Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90.

21 January 2018

1 reference

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A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

21 January 2018

1 reference

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Nucleotide sequence of the yeast cell division cycle start genes CDC28, CDC36, CDC37, and CDC39, and a structural analysis of the predicted products

21 January 2018

1 reference

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Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila.

21 January 2018

1 reference

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A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209494200

The oncoprotein kinase chaperone CDC37 functions as an oncogene in mice and collaborates with both c-myc and cyclin D1 in transformation of multiple tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209494200

Cdc37 is a molecular chaperone with specific functions in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209494200

Temperature-sensitive ZAP70 mutants degrading through a proteasome-independent pathway. Restoration of a kinase domain mutant by Cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209494200

Induction of human Cdc37 in prostate cancer correlates with the ability of targeted Cdc37 expression to promote prostatic hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209494200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209494200

1 reference

22 September 2017

1 reference