Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line (Q40678630)

22 September 2017

Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line (English)

1 reference

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7 October 2022

1 reference

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post-translational protein modification

7 October 2022

1 reference

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7 October 2022

3

P. K. Jackson

1 reference

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7 October 2022

author name string

G. Q. Daley

1

1 reference

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7 October 2022

R. A. Van Etten

2

1 reference

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7 October 2022

A. Bernards

4

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7 October 2022

D. Baltimore

5

1 reference

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7 October 2022

language of work or name

English

0 references

publication date

1 April 1992

1 reference

PMCID

369630

full work available at URL

22 September 2017

http://mcb.asm.org/cgi/content/abstract/12/4/1864

online access status

open access

1 reference

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1549131/pdf/?tool=EBI

7 October 2022

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1549131

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1549131/?tool=EBI

7 October 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1549131

https://europepmc.org/articles/PMC369630

7 October 2022

1 reference

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https://europepmc.org/articles/PMC369630?pdf=render

7 October 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

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Molecular and Cellular Biology

7 October 2022

published in

1 reference

22 September 2017

12

1 reference

22 September 2017

4

1 reference

22 September 2017

1864-1871

1 reference

Myristic acid is attached to the transforming protein of Rous sarcoma virus during or immediately after synthesis and is present in both soluble and membrane-bound forms of the protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Lethal effect of the abelson murine leukemia virus transforming gene product

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Mutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

The six amino-terminal amino acids of p60src are sufficient to cause myristylation of p21v-ras

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Purification and characterization of yeast myristoyl CoA:protein N-myristoyltransferase.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

The membrane-binding domain and myristylation of p60v-src are not essential for stimulation of cell proliferation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Integrins: a family of cell surface receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Rous sarcoma virus transforming protein lacking myristic acid phosphorylates known polypeptide substrates without inducing transformation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Two classes of fatty acid acylated proteins exist in eukaryotic cells.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Fine structural mapping of a critical NH2-terminal region of p60src

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Reconstitution of the Rous sarcoma virus transforming protein pp60v-src into phospholipid vesicles

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

A bcr-v-abl oncogene induces lymphomas in transgenic mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

N-terminal mutations activate the leukemogenic potential of the myristoylated form of c-abl

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Deletion of an N-terminal regulatory domain of the c-abl tyrosine kinase activates its oncogenic potential

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

A glycoprotein in the plasma membrane matrix as a major potential substrate of p60v-src

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Implicating the bcr/abl gene in the pathogenesis of Philadelphia chromosome-positive human leukemia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

The src protein contains multiple domains for specific attachment to membranes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Direct transformation of 3T3 cells by Abelson murine leukaemia virus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

bcr-abl oncogene renders myeloid cell line factor independent: potential autocrine mechanism in chronic myeloid leukemia.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

The CML-specific P210 bcr/abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Acute leukaemia in bcr/abl transgenic mice

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369630

High affinity binding of an N-terminal myristoylated p60src peptide

15 June 2018

1 reference

12 December 2020

Specific and saturable binding of pp60v-src to plasma membranes: evidence for a myristyl-src receptor

1 reference

12 December 2020

Amino-terminal processing of proteins by N-myristoylation. Substrate specificity of N-myristoyl transferase

1 reference

12 December 2020

Acylation of proteins with myristic acid occurs cotranslationally

1 reference

12 December 2020

Fatty acylation of cellular proteins. Temporal and subcellular differences between palmitate and myristate acylation

1 reference

12 December 2020

Myristylation of gag-onc fusion proteins in mammalian transforming retroviruses

1 reference

12 December 2020

Identification of a 32K plasma membrane protein that binds to the myristylated amino-terminal sequence of p60v-src

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.12.4.1864

1 reference

PMCID

369630

10.1128/MCB.12.4.1864-1871.1992

22 September 2017

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1549131

7 October 2022

1 reference

22 September 2017

1 reference

PMCID

369630