Dimerization of presenilin-1 in vivo: suggestion of novel regulatory mechanisms leading to higher order complexes (Q40676340)

22 September 2017

title

Dimerization of presenilin-1 in vivo: suggestion of novel regulatory mechanisms leading to higher order complexes (English)

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22 September 2017

Sébastien S Hébert

1

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22 September 2017

Chantal Godin

2

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22 September 2017

Takami Tomiyama

3

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22 September 2017

Hiroshi Mori

4

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22 September 2017

Georges Lévesque

5

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22 September 2017

publication date

1 January 2003

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Biochemical and Biophysical Research Communications

22 September 2017

published in

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22 September 2017

volume

301

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22 September 2017

issue

1

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22 September 2017

page(s)

119-126

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Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin

22 September 2017

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7 January 2021

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Aggresomes: a cellular response to misfolded proteins

7 January 2021

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The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex

7 January 2021

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Evidence for phosphorylation and oligomeric assembly of presenilin 1.

7 January 2021

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The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

7 January 2021

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Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation

7 January 2021

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Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

7 January 2021

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Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

7 January 2021

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Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.

7 January 2021

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Binding partners of Alzheimer's disease proteins: are they physiologically relevant?

7 January 2021

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The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation

7 January 2021

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Missense mutation E318G of the presenilin-1 gene appears to be a nonpathogenic polymorphism.

7 January 2021

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Alzheimer's presenilin 1 gene expression in platelets and megakaryocytes. Identification of a novel splice variant

7 January 2021

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The presenilin genes: a new gene family involved in Alzheimer disease pathology

7 January 2021

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Endoproteolytic processing and stabilization of wild-type and mutant presenilin

7 January 2021

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The biological and pathological function of the presenilin-1 Deltaexon 9 mutation is independent of its defect to undergo proteolytic processing

7 January 2021

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Presenilin 1 cleavage is a universal event in human organs

7 January 2021

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Amyloidogenic function of the Alzheimer's disease-associated presenilin 1 in the absence of endoproteolysis

7 January 2021

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G-protein-coupled receptors function as oligomers in vivo

7 January 2021

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A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

7 January 2021

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Dual roles of proteasome in the metabolism of presenilin 1.

7 January 2021

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Cell surface expression of the Alzheimer disease-related presenilin proteins

7 January 2021

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Detection of the presenilin 1 COOH-terminal fragment in the extracellular compartment: a release enhanced by apoptosis

7 January 2021

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Presenilin-1 immunoreactivity is localized intracellularly in Alzheimer's disease brain, but not detected in amyloid plaques

7 January 2021

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Abnormal gel-electrophoretic behavior of presenilin 1 and it's fragment

7 January 2021

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Identification and characterization of presenilin I-467, I-463 and I-374.

7 January 2021

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Homodimerization of presenilin N-terminal fragments is affected by mutations linked to Alzheimer's disease

7 January 2021

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Evidence That Intramolecular Associations between Presenilin Domains Are Obligatory for Endoproteolytic Processing

7 January 2021

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Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

7 January 2021

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An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.

7 January 2021

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Skeletal and CNS defects in Presenilin-1-deficient mice

7 January 2021

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Mice lacking both presenilin genes exhibit early embryonic patterning defects

7 January 2021

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Presenilins as therapeutic targets for the treatment of Alzheimer's disease

7 January 2021

1 reference

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Cytoplasmic presenilin aggregates in proteasome inhibitor-treated cells.

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-291X(02)02984-4

1 reference

22 September 2017

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