The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease (Q40669171)

22 September 2017

The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease (English)

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22 September 2017

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5

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22 September 2017

1

Ronit Sharon

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22 September 2017

6

Dennis J Selkoe

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22 September 2017

3

Matthew P Frosch

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22 September 2017

Ifat Bar-Joseph

2

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PubMed ID

12597857

22 September 2017

Dominic M Walsh

series ordinal

4

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PubMed ID

12597857

22 September 2017

language of work or name

English

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publication date

1 February 2003

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22 September 2017

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22 September 2017

37

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22 September 2017

583-595

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22 September 2017

4

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Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

22 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

A novel N18TG2 x mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Sphingomyelin in Lewy inclusion bodies in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Experimental allergic encephalomyelitis. An encephalitogenic basic protein from bovine myelin

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

A Drosophila model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Transport of fatty acids across membranes by the diffusion mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids?

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Allergic encephalomyelitis: Preparation of the encephalitogenic basic protein from bovine brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Chaperone-like activity of synucleins

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Alpha-synuclein in Lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Chronic n-3 polyunsaturated fatty acid diet-deficiency acts on dopamine metabolism in the rat frontal cortex: a microdialysis study.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

Chronic n-3 polyunsaturated fatty acid deficiency alters dopamine vesicle density in the rat frontal cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900024-2

7 January 2021

10.1016/S0896-6273(03)00024-2

Identifiers

DOI

1 reference

22 September 2017

1 reference

PubMed ID

12597857