Interleukin-27 (IL-27) Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17-Neutrophil Response (Q40651582)

22 September 2017

Interleukin-27 (IL-27) Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17-Neutrophil Response (English)

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22 September 2017

visceral leishmaniasis

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1

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7 June 2020

Vanessa Carregaro

7

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7 June 2020

Joao S Silva

8

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7 June 2020

author name string

Manuela S L Nascimento

2

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7 June 2020

Marcela Davoli-Ferreira

3

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7 June 2020

Lais A Sacramento

4

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7 June 2020

Mikhael H F Lima

5

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7 June 2020

Roque P Almeida

6

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7 June 2020

language of work or name

English

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publication date

31 May 2016

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22 September 2017

Infection and Immunity

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7 June 2020

volume

84

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7 June 2020

issue

8

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7 June 2020

page(s)

2289-2298

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describes a project that uses

7 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4962641/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

The Severity of Visceral Leishmaniasis Correlates with Elevated Levels of Serum IL-6, IL-27 and sCD14.

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Toll-like receptor 9 signaling in dendritic cells regulates neutrophil recruitment to inflammatory foci following Leishmania infantum infection.

22 September 2017

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TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes

22 September 2017

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An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4962641

IL-27 enhances Leishmania amazonensis infection via ds-RNA dependent kinase (PKR) and IL-10 signaling

22 September 2017

1 reference

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Neutrophils have a protective role during early stages of Leishmania amazonensis infection in BALB/c mice.

22 September 2017

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In vivo action of IL-27: reciprocal regulation of Th17 and Treg cells in collagen-induced arthritis

22 September 2017

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Neutrophil recruitment and function in health and inflammation

22 September 2017

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Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response

22 September 2017

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Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1.

22 September 2017

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Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-leishmania response

22 September 2017

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Compartment-specific remodeling of splenic micro-architecture during experimental visceral leishmaniasis.

22 September 2017

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BALB/c mice infected with antimony treatment refractory isolate of Leishmania braziliensis present severe lesions due to IL-4 production

22 September 2017

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IL-27 and IL-21 are associated with T cell IL-10 responses in human visceral leishmaniasis

22 September 2017

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Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process

22 September 2017

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IL-27 regulates IL-10 and IL-17 from CD4+ cells in nonhealing Leishmania major infection

22 September 2017

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Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani

22 September 2017

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The inhibitory cytokine IL-35 contributes to regulatory T-cell function

22 September 2017

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Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to leishmania donovani infection but develop severe liver immunopathology

22 September 2017

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T helper (h)1/Th2 and Leishmania: paradox rather than paradigm

22 September 2017

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EBV-induced gene 3 transcription is induced by TLR signaling in primary dendritic cells via NF-kappa B activation.

22 September 2017

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WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

22 September 2017

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22 September 2017

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22 September 2017

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Culture microtitration: a sensitive method for quantifying Leishmania infantum in tissues of infected mice

22 September 2017

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Interleukin 17A acts synergistically with interferon γ to promote protection against Leishmania infantum infection

22 September 2017

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A limiting dilution assay for quantifying Leishmania major in tissues of infected mice

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15 June 2018

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T cell subset and cytokine profiles in human visceral leishmaniasis during active and asymptomatic or sub-clinical infection with Leishmania donovani

19 August 2018

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Impaired Th1 responses in mice deficient in Epstein-Barr virus-induced gene 3 and challenged with physiological doses of Leishmania major

19 August 2018

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IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27245409

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27245409

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/IAI.00283-16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27245409%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27245409%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference