Valproate induces replication-independent active DNA demethylation (Q40647716)

22 September 2017

Valproate induces replication-independent active DNA demethylation (English)

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22 September 2017

Nancy Detich

1

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22 September 2017

Veronica Bovenzi

series ordinal

2

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22 September 2017

Moshe Szyf

series ordinal

3

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22 September 2017

language of work or name

English

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publication date

14 May 2003

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Journal of Biological Chemistry

22 September 2017

7

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based on heuristic

inferred from page(s)

published in

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22 September 2017

278

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22 September 2017

30

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22 September 2017

27586-27592

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CpG methylation, chromatin structure and gene silencing-a three-way connection

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DNA hypomethylating agents 5-aza-2'-deoxycytidine and valproate increase neuronal 5-lipoxygenase mRNA.

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Active demethylation of the paternal genome in the mouse zygote

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The dynamics of myogenin site-specific demethylation is strongly correlated with its expression and with muscle differentiation.

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Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process

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DNA methylation is a reversible biological signal

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Demethylase activity is directed by histone acetylation

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Autonomous replication of a DNA fragment containing the chromosomal replication origin of the human c-myc gene

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The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.

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Differential effects of mood stabilizers on Fos/Jun proteins and AP-1 DNA binding activity in human neuroblastoma SH-SY5Y cells.

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Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy

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Glucose metabolism in cancer. Evidence that demethylation events play a role in activating type II hexokinase gene expression

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Transient forebrain ischemia alters the mRNA expression of methyl DNA-binding factors in the adult rat hippocampus.

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Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

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Identifiers

DOI

10.1074/JBC.M303740200

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22 September 2017

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