Novel insights into the regulation of the timeless protein. (Q40639588)

22 September 2017

Novel insights into the regulation of the timeless protein (English)

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12 May 2020

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GOA release 2020-03-11

Period Dmel_CG2647

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GOA release 2020-03-11

author name string

Lesley J Ashmore

1

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12 May 2020

Sriram Sathyanarayanan

2

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12 May 2020

David W Silvestre

3

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12 May 2020

Mark M Emerson

4

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12 May 2020

Peter Schotland

5

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12 May 2020

Amita Sehgal

6

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12 May 2020

language of work or name

English

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publication date

1 August 2003

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22 September 2017

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740606&resulttype=core&format=json

12 May 2020

volume

23

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12 May 2020

page(s)

7810-7819

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12 May 2020

issue

21

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PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription

12 May 2020

cites work

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12 December 2020

mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop

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12 December 2020

A role for the proteasome in the light response of the timeless clock protein.

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12 December 2020

Interlocked Feedback Loops Within the Drosophila Circadian Oscillator

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12 December 2020

Altered entrainment and feedback loop function effected by a mutant period protein.

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12 December 2020

A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals

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12 December 2020

A TIMELESS-independent function for PERIOD proteins in the Drosophila clock

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12 December 2020

Molecular analysis of zebrafish photolyase/cryptochrome family: two types of cryptochromes present in zebrafish.

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12 December 2020

Isolation and analysis of six timeless alleles that cause short- or long-period circadian rhythms in Drosophila

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12 December 2020

Mechanisms of action of transcription activation and repression domains

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12 December 2020

Molecular components of the circadian system in Drosophila

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12 December 2020

Role of molecular oscillations in generating behavioral rhythms in Drosophila.

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12 December 2020

Regulation of the cycling of timeless (tim) RNA.

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12 December 2020

A new role for cryptochrome in a Drosophila circadian oscillator.

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12 December 2020

Circadian photoreception in Drosophila: functions of cryptochrome in peripheral and central clocks.

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12 December 2020

A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock.

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12 December 2020

Light-dependent interaction between Drosophila CRY and the clock protein PER mediated by the carboxy terminus of CRY.

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12 December 2020

Photic signaling by cryptochrome in the Drosophila circadian system

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12 December 2020

Nuclear export of mammalian PERIOD proteins

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12 December 2020

Circadian regulation of gene expression systems in the Drosophila head

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12 December 2020

Microarray analysis and organization of circadian gene expression in Drosophila

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12 December 2020

Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein

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12 December 2020

Influence of the period-dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster

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12 December 2020

Sequential nuclear accumulation of the clock proteins period and timeless in the pacemaker neurons of Drosophila melanogaster.

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12 December 2020

Genome-wide expression analysis in Drosophila reveals genes controlling circadian behavior.

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12 December 2020

Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime.

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12 December 2020

Genetic analysis of the circadian system in Drosophila melanogaster and mammals

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12 December 2020

VRILLE feeds back to control circadian transcription of Clock in the Drosophila circadian oscillator

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12 December 2020

New role of zCRY and zPER2 as regulators of sub-cellular distributions of zCLOCK and zBMAL proteins

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12 December 2020

vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock

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12 December 2020

Changes in abundance or structure of the per gene product can alter periodicity of the Drosophila clock.

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12 December 2020

Isolation of timeless by PER protein interaction: defective interaction between timeless protein and long-period mutant PERL

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12 December 2020

Suppression of PERIOD protein abundance and circadian cycling by the Drosophila clock mutation timeless

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12 December 2020

The period clock gene is expressed in central nervous system neurons which also produce a neuropeptide that reveals the projections of circadian pacemaker cells within the brain of Drosophila melanogaster

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12 December 2020

Temporally regulated nuclear entry of the Drosophila period protein contributes to the circadian clock.

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12 December 2020

Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression

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12 December 2020

Block in nuclear localization of period protein by a second clock mutation, timeless

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12 December 2020

A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation

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12 December 2020

Light-induced degradation of TIMELESS and entrainment of the Drosophila circadian clock.

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12 December 2020

Resetting the Drosophila clock by photic regulation of PER and a PER-TIM complex.

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12 December 2020

A light-entrainment mechanism for the Drosophila circadian clock

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12 December 2020

Regulation of the Drosophila protein timeless suggests a mechanism for resetting the circadian clock by light

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12 December 2020

Regulation of nuclear entry of the Drosophila clock proteins period and timeless.

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12 December 2020

Spatial and temporal expression of the period and timeless genes in the developing nervous system of Drosophila: newly identified pacemaker candidates and novel features of clock gene product cycling.

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12 December 2020

Post-transcriptional regulation contributes to Drosophila clock gene mRNA cycling

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12 December 2020

Conserved regions of the timeless (tim) clock gene in Drosophila analyzed through phylogenetic and functional studies

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12 December 2020

Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim.

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12 December 2020

Circadian regulation of a Drosophila homolog of the mammalian Clock gene: PER and TIM function as positive regulators

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12 December 2020

Alterations of per RNA in noncoding regions affect periodicity of circadian behavioral rhythms

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12 December 2020

The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER-TIM complex.

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12 December 2020

The 69 bp circadian regulatory sequence (CRS) mediates per-like developmental, spatial, and circadian expression and behavioral rescue in Drosophila.

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12 December 2020

TIMELESS-dependent positive and negative autoregulation in the Drosophila circadian clock

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12 December 2020

10.1523/JNEUROSCI.23-21-07810.2003

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740606&resulttype=core&format=json

12 May 2020

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12 May 2020

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