Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis. (Q40637766)

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scientific article published on September 2003

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English	Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis.	scientific article published on September 2003

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7 November 2019

Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis (English)

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7 November 2019

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Christopher S Gondi

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7 November 2019

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Jasti S Rao

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7 November 2019

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Sajani S Lakka

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7 November 2019

Niranjan Yanamandra

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7 November 2019

Khawar Siddique

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7 November 2019

Dzung H Dinh

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7 November 2019

William C Olivero

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7 November 2019

Meena Gujrati

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1 September 2003

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38

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7 November 2019

5967-5975

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7 November 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206535

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Down-regulation of integrin alpha(v)beta(3) expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense urokinase-type plasminogen activator receptor (uPAR) and sense p16 genes.

1 reference

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Urokinase-type plasminogen activator is effective in fibrin clearance in the absence of its receptor or tissue-type plasminogen activator

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Induction of matrix metalloproteinase-9 requires a polymerized actin cytoskeleton in human malignant glioma cells.

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The Jak/Stat pathway and urokinase receptor signaling in human aortic vascular smooth muscle cells.

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The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

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Urokinase-type plasminogen activator and its inhibitor PAI-1: predictors of poor response to tamoxifen therapy in recurrent breast cancer

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Inhibition of in vivo tumorigenicity and invasiveness of a human glioblastoma cell line transfected with antisense uPAR vectors

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21 January 2018

Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598

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Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin

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Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy

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21 January 2018

Suppression of glioma invasion and growth by adenovirus-mediated delivery of a bicistronic construct containing antisense uPAR and sense p16 gene sequences

1 reference

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7 January 2021

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Deregulation of the signaling pathways controlling urokinase production. Its relationship with the invasive phenotype.

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The urokinase receptor. A cell surface, regulated chemokine.

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Urokinase receptor-dependent upregulation of smooth muscle cell adhesion to vitronectin by urokinase

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The urokinase plasminogen activator receptor in the regulation of the actin cytoskeleton and cell motility

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Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma.

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Increased cell-surface urokinase in advanced ovarian cancer.

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Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice

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7 January 2021

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Purification of zymogen to plasminogen activator from human glioblastoma cells by affinity chromatography with monoclonal antibody.

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7 January 2021

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Co-expression of urokinase-type plasminogen activator and its receptor in human gastric-cancer cell lines correlates with their invasiveness and tumorigenicity

1 reference

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7 January 2021

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Tumor-associated urokinase-type plasminogen activator: biological and clinical significance

1 reference

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7 January 2021

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Identifiers

10.1038/SJ.ONC.1206535

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7 November 2019

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7 November 2019

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