Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling (Q40637759)

22 September 2017

Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling (English)

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22 September 2017

Wen-Mei Yu

1

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22 September 2017

Teresa S Hawley

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2

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22 September 2017

Robert G Hawley

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3

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22 September 2017

Cheng-Kui Qu

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4

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22 September 2017

language of work or name

English

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publication date

1 September 2003

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22 September 2017

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22 September 2017

22

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22 September 2017

5995-6004

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22 September 2017

38

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206846

22 September 2017

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cites work

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

SHP1 and SHP2 protein-tyrosine phosphatases associate with betac after interleukin-3-induced receptor tyrosine phosphorylation. Identification of potential binding sites and substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

The phosphotyrosine phosphatase SHP-2 participates in a multimeric signaling complex and regulates T cell receptor (TCR) coupling to the Ras/mitogen-activated protein kinase (MAPK) pathway in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

Expression of a dominant negative SHP-2 in transgenic mice induces insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

The Shp-2 tyrosine phosphatase has opposite effects in mediating the activation of extracellular signal-regulated and c-Jun NH2-terminal mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

Combinatorial control of the specificity of protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

Engagement of Gab1 and Gab2 in erythropoietin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

p85 subunit of PI3 kinase does not bind to human Flt3 receptor, but associates with SHP2, SHIP, and a tyrosine-phosphorylated 100-kDa protein in Flt3 ligand-stimulated hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

Altered expression of protein-tyrosine phosphatase 2C in 293 cells affects protein tyrosine phosphorylation and mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Shc associates with the IL-3 receptor β subunit, SHIP and Gab2 following IL-3 stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Signaling by the cytokine receptor superfamily

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Roles for the protein tyrosine phosphatase SHP-2 in cytoskeletal organization, cell adhesion and cell migration revealed by overexpression of a dominant negative mutant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Definition of the role of tyrosine residues of the common beta subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Signaling domains of the beta c chain of the GM-CSF/IL-3/IL-5 receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Jak2 is essential for signaling through a variety of cytokine receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Role of the SHP-2 tyrosine phosphatase in cytokine-induced signaling and cellular response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Genetic evidence that Shp-2 tyrosine phosphatase is a signal enhancer of the epidermal growth factor receptor in mammals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Immortalization of yolk sac-derived precursor cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206846

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206846

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Dimensions Publication ID

22 September 2017

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