FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells (Q40612629)

22 September 2017

FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells (English)

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22 September 2017

Tsuyoshi Imai

1

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22 September 2017

Souichi Adachi

2

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22 September 2017

Koichi Nishijo

3

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22 September 2017

Masatoshi Ohgushi

4

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22 September 2017

Masayuki Okada

5

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22 September 2017

Takahiro Yasumi

6

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22 September 2017

Ken-ichiro Watanabe

7

1 reference

22 September 2017

Ryuta Nishikomori

8

1 reference

22 September 2017

Tomitaka Nakayama

9

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22 September 2017

Shin Yonehara

10

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22 September 2017

Junya Toguchida

11

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22 September 2017

Tatsutoshi Nakahata

12

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22 September 2017

language of work or name

English

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publication date

1 December 2003

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22 September 2017

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22 September 2017

22

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22 September 2017

9231-9242

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22 September 2017

58

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207184

22 September 2017

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Bcl-2 and the outer mitochondrial membrane in the inactivation of cytochrome c during Fas-mediated apoptosis

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p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells

21 January 2018

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Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein

21 January 2018

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Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Osteosarcomas and other cancers of bone

21 January 2018

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A comparison of two short intensive adjuvant chemotherapy regimens in operable osteosarcoma of limbs in children and young adults: the first study of the European Osteosarcoma Intergroup

21 January 2018

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A protein phosphatase is involved in the inhibition of histone deacetylation by sodium butyrate.

21 January 2018

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Adjuvant chemotherapy for osteosarcoma: a randomized prospective trial

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Modulation of resistance to anti-APO-1-induced apoptosis in osteosarcoma cells by cytokines

21 January 2018

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

21 January 2018

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Modifying histones to tame cancer: clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors

21 January 2018

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Histone acetylation in chromatin structure and transcription

21 January 2018

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Humanization of the mouse anti-Fas antibody HFE7A and crystal structure of the humanized HFE7A Fab fragment

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Cellular stress response and apoptosis in cancer therapy.

21 January 2018

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The role of p53 and pRB in apoptosis and cancer

21 January 2018

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Osteoblast apoptosis and bone turnover

21 January 2018

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The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis

21 January 2018

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Induction of apoptosis by cancer chemotherapy.

21 January 2018

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Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression.

21 January 2018

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Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines

21 January 2018

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In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice.

21 January 2018

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Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells

21 January 2018

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Improved prognosis of children with osteosarcoma metastatic to the lung(s) at the time of diagnosis

21 January 2018

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Histone deacetylase inhibitors as new cancer drugs

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Doxorubicin sensitizes human bladder carcinoma cells to Fas-mediated cytotoxicity

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Morphological and biological heterogeneity of three tumorigenic cell lines derived from a single p53-/- osteoblast-like cell line, MMC2.

21 January 2018

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Apoptosis by death factor

21 January 2018

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21 January 2018

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Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

From bench to clinic with apoptosis-based therapeutic agents

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Chronic oral administration of CI-994: a phase 1 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Primary osteogenic sarcoma. The rationale for preoperative chemotherapy and delayed surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

P21-dependent g(1)arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Effects of FK228, a novel histone deacetylase inhibitor, on human lymphoma U-937 cells in vitro and in vivo

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Transcriptional induction of the osteocalcin gene during osteoblast differentiation involves acetylation of histones h3 and h4.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Histone acetylation and transcriptional regulatory mechanisms

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Fungal metabolite FR901228 inhibits c-Myc and Fas ligand expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Sequential 5-Aza-2 deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Death receptor Fas and autoimmune disease: from the original generation to therapeutic application of agonistic anti-Fas monoclonal antibody

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

The role of CD95 system in chemotherapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

7 January 2021

Chemosensitivity of solid tumor cellsin vitro is related to activation of the CD95 system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

7 January 2021

Osteosarcoma and other bone cancers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

7 January 2021

Chemotherapy for nonmetastatic osteogenic sarcoma: the Memorial Sloan-Kettering experience

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

7 January 2021

Osteosarcoma of the pelvis: experience of the Cooperative Osteosarcoma Study Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

7 January 2021

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

7 January 2021

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207184

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207184

1 reference

Dimensions Publication ID

22 September 2017

0 references

1 reference