Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells (Q40600919)

21 September 2017

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells (English)

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21 September 2017

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T Kanzawa

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21 September 2017

I M Germano

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T Komata

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H Ito

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Y Kondo

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S Kondo

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1 April 2004

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Cell Death & Differentiation

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21 September 2017

448-457

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401359

21 September 2017

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Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials

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Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma

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NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA.

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Chemosensitivity to triazene compounds and O6-alkylguanine-DNA alkyltransferase levels: studies with blasts of leukaemic patients

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Involvement of the mismatch repair system in temozolomide-induced apoptosis.

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Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy.

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Molecular response of human glioblastoma multiforme cells to ionizing radiation: cell cycle arrest, modulation of the expression of cyclin-dependent kinase inhibitors, and autophagy

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

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Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

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Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells.

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7 January 2021

Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

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7 January 2021

Inhibitors of vacuolar-type H(+)-ATPase suppresses proliferation of cultured cells

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7 January 2021

SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation

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7 January 2021

Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.

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Autophagy and other vacuolar protein degradation mechanisms

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The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes

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Phosphoinositide 3-kinases: a conserved family of signal transducers

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Signalling through the lipid products of phosphoinositide-3-OH kinase

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Phosphoinositides as regulators in membrane traffic

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7 January 2021

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

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7 January 2021

Vacuolar import of proteins and organelles from the cytoplasm

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7 January 2021

Induction of autophagy and inhibition of tumorigenesis by beclin 1

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7 January 2021

The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

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7 January 2021

Defective acidification in human breast tumor cells and implications for chemotherapy.

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7 January 2021

Programmed cell death (PCD). Apoptosis, autophagic PCD, or others?

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7 January 2021

Combination therapy of malignant glioma cells with 2-5A-antisense telomerase RNA and recombinant adenovirus p53.

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Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

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A novel telomerase-specific gene therapy: gene transfer of caspase-8 utilizing the human telomerase catalytic subunit gene promoter

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401359

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Dimensions Publication ID

21 September 2017

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