Alterations in the p16(INK4a) and p53 tumor suppressor genes of hTERT-immortalized human fibroblasts. (Q40595709)

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17 November 2019

title

Alterations in the p16(INK4a) and p53 tumor suppressor genes of hTERT-immortalized human fibroblasts (English)

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17 November 2019

5

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17 November 2019

Roger Reddel

6

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17 November 2019

author name string

Jane R Noble

1

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17 November 2019

Ze-Huai Zhong

2

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17 November 2019

Axel A Neumann

3

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17 November 2019

John R Melki

4

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17 November 2019

language of work or name

English

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publication date

1 April 2004

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17 November 2019

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17 November 2019

volume

23

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17 November 2019

issue

17

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17 November 2019

page(s)

3116-3121

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207440

17 November 2019

exact match

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cites work

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Clonal variation in phenotype and life span of human embryonic fibroblasts (MRC-5) transduced with the catalytic component of telomerase (hTERT).

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The serial cultivation of human diploid cell strains

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Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.

21 January 2018

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Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.

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The IARC TP53 database: new online mutation analysis and recommendations to users

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Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen

21 January 2018

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The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activity

21 January 2018

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7 January 2021

SV40-INDUCED TRANSFORMATION OF HUMAN DIPLOID CELLS: CRISIS AND RECOVERY

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7 January 2021

Mutation screening of theCDKN2A promoter in melanoma families

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7 January 2021

Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts

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7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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7 January 2021

Cytosine methylation: quantitation by automated genomic sequencing and GENESCAN analysis.

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7 January 2021

Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids

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7 January 2021

The role of senescence and immortalization in carcinogenesis

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7 January 2021

Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207440

7 January 2021

Association of p16(INK4a) and pRb inactivation with immortalization of human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207440

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.279.5349.349

Identifiers

DOI

10.1038/SJ.ONC.1207440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14743210%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 November 2019

1021416705

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1 reference