Tip, an Lck-interacting protein of Herpesvirus saimiri, causes Fas- and Lck-dependent apoptosis of T lymphocytes (Q40579458)

21 September 2017

Tip, an Lck-interacting protein of Herpesvirus saimiri, causes Fas- and Lck-dependent apoptosis of T lymphocytes (English)

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21 September 2017

Muneer G Hasham

1

1 reference

PubMed ID

15016553

21 September 2017

Alexander Y Tsygankov

series ordinal

2

1 reference

PubMed ID

15016553

21 September 2017

language of work or name

English

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publication date

1 March 2004

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21 September 2017

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21 September 2017

320

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21 September 2017

313-329

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21 September 2017

2

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The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype

21 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Stable growth transformation of human T lymphocytes by herpesvirus saimiri

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

The product of the Herpesvirus saimiri open reading frame 1 (tip) interacts with T cell-specific kinase p56lck in transformed cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Herpesvirus saimiri strategies for T cell stimulation and transformation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Activation induces apoptosis in Herpesvirus saimiri-transformed T cells independent of CD95 (Fas, APO-1).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Characterization of Herpesvirus saimiri-transformed T lymphocytes from common variable immunodeficiency patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Comparative analysis of the transforming mechanisms of Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus, and Herpesvirus saimiri

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Direct binding and activation of STAT transcription factors by the herpesvirus saimiri protein tip.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Activation of the lck tyrosine-protein kinase by the binding of the tip protein of herpesvirus saimiri in the absence of regulatory tyrosine phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Activation of the Lck tyrosine protein kinase by the Herpesvirus saimiri tip protein involves two binding interactions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Altered replication of human immunodeficiency virus type 1 (HIV-1) in T cell lines retrovirally transduced to express Herpesvirus saimiri proteins StpC and/or Tip.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Lck protein tyrosine kinase is a key regulator of T-cell activation and a target for signal intervention by Herpesvirus saimiri and other viral gene products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Association of the viral oncoprotein STP-C488 with cellular ras.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Identification of transforming genes of subgroup A and C strains of Herpesvirus saimiri

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Identification of Lck-binding elements in tip of herpesvirus saimiri

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Herpesvirus saimiri as a model for gammaherpesvirus oncogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

The herpesvirus saimiri tip484 and tip488 proteins both stimulate lck tyrosine protein kinase activity in vivo and in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Herpesvirus saimiri transformation of HIV type 1 suppressive CD8+ lymphocytes from an HIV type 1-infected asymptomatic individual

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Regulation of Epstein-Barr virus latency by latent membrane protein 2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Successful in vitro immortalization of human intestinal mucosal lymphocytes with Herpesvirus saimiri

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

IL-2 independent growth and cytotoxicity of herpesvirus saimiri-infected human CD8 cells and involvement of two open reading frame sequences of the virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

T cell transformation with Herpesvirus saimiri: a tool for neuroimmunological research

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Herpesvirus saimiri replaces ZAP-70 for CD3- and CD2-mediated T cell activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Herpesvirus saimiri oncoproteins Tip and StpC synergistically stimulate NF-kappaB activity and interleukin-2 gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Herpes virus saimiri-transformed human T lymphocytes: normal functional phenotype and preserved T cell receptor signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Abnormal T cell receptor signal transduction of CD4 Th cells in X-linked lymphoproliferative syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Herpesviral protein targets a cellular WD repeat endosomal protein to downregulate T lymphocyte receptor expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Generation of an immortalized human CD4+ T cell clone inhibiting tumor growth in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Negative regulation of Lck by Cbl ubiquitin ligase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Dominant clones in immortalized T-cell lines from rheumatoid arthritis synovial membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Generation of CD4+ and CD8+ T-cell clones from PBLs of HIV-1 infected subjects using herpesvirus saimiri

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Human immunodeficiency virus type 1 (HIV-1) infection of herpesvirus saimiri-immortalized human CD4-positive T lymphoblastoid cells: evidence of enhanced HIV-1 replication and cytopathic effects caused by endogenous interferon-gamma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

An ELISA for detection of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Herpesvirus saimiri-immortalized human T-cells support long-term, high titred replication of human immunodeficiency virus types 1 and 2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Enhanced replication of M-tropic HIV-1 strains in Herpesvirus saimiri immortalised T-cells which express CCR5.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Herpesvirus saimiri-immortalized human lymphocytes: novel hosts for analyzing HIV type 1 in vitro neutralization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Transformation of human T-cell clones by Herpesvirus saimiri: intact antigen recognition by autonomously growing myelin basic protein-specific T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Selective activation of T cell kinase p56lck by Herpesvirus saimiri protein tip.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Selection following isolation of human immunodeficiency virus type 1 in peripheral blood mononuclear cells and herpesvirus saimiri-transformed T cells is comparable

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

7 January 2021

Functional phenotype of transformed human alphabeta and gammadelta T cells determined by different subgroup C strains of herpesvirus Saimiri

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

7 January 2021

Enhanced downregulation of Lck-mediated signal transduction by a Y114 mutation of herpesvirus Saimiri tip.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

7 January 2021

Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

7 January 2021

The superantigen-homologous viral immediate-early gene ie14/vsag in herpesvirus saimiri-transformed human T cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

7 January 2021

Role of cellular tumor necrosis factor receptor-associated factors in NF-kappaB activation and lymphocyte transformation by herpesvirus Saimiri STP.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

7 January 2021

Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

7 January 2021

Resistance against syncytium-inducing human immunodeficiency virus type 1 (HIV-1) in selected CD4(+) T cells from an HIV-1-infected nonprogressor: evidence of a novel pathway of resistance mediated by a soluble factor(s) that acts after virus entry

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2003.11.032

7 January 2021

10.1016/J.VIROL.2003.11.032

Identifiers

DOI

1 reference

21 September 2017

1 reference

PubMed ID

15016553