Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins (Q40568027)

21 September 2017

Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins (English)

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21 September 2017

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Paul Greengard

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21 September 2017

Marc Blondel

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Prokopios Magiatis

object named as

Prokopios Magiatis

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Martine Ffrench

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object named as

Martine Ffrench

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21 September 2017

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Laurent Meijer

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21 September 2017

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Gordon L Hager

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Alexios-Leandros Skaltsounis

21 September 2017

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object named as

Leandros Skaltsounis

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21 September 2017

Marie Knockaert

1

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21 September 2017

Stéphane Bach

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21 September 2017

Maryse Leost

4

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21 September 2017

Cem Elbi

5

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21 September 2017

Scott R Nagy

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21 September 2017

Dalho Han

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21 September 2017

Michael Denison

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21 September 2017

Xiaozhou P Ryan

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21 September 2017

Panos Polychronopoulos

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21 September 2017

language of work or name

English

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publication date

1 May 2004

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21 September 2017

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21 September 2017

4400-4412

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207535

21 September 2017

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cites work

Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

The specificities of protein kinase inhibitors: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Characterization of in vitro metabolites of the aryl hydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole by liquid chromatography-mass spectrometry and NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Sequential dephosphorylation of p34(cdc2) on Thr-14 and Tyr-15 at the prophase/metaphase transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

The aryl hydrocarbon receptor in anticancer drug discovery: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

The commercial production of chemicals using pathway engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Tyrian Purple: 6,6’-Dibromoindigo and Related Compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Anti-mitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate

21 January 2018

1 reference

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Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Cell-cycle, protein content, and nuclear size in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Identification of functional domains of the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Oxidation of indole by cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Aryl hydrocarbon receptors: diversity and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

The aryl hydrocarbon receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Activation of the Ah receptor by tryptophan and tryptophan metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Homology modelling of the nuclear receptors: human oestrogen receptorbeta (hERbeta), the human pregnane-X-receptor (PXR), the Ah receptor (AhR) and the constitutive androstane receptor (CAR) ligand binding domains from the human oestrogen receptor a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

The Jun N-terminal kinase inhibitor SP600125 is a ligand and antagonist of the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Construction of reporter yeasts for mouse aryl hydrocarbon receptor ligand activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Pharmacological inhibitors of cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Arylhydrocarbon receptor expression in the human endometrium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Identification of an indigo precursor from leaves of Isatis tinctoria (Woad).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

GSK-3-selective inhibitors derived from Tyrian purple indirubins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Expression of the human aryl hydrocarbon receptor complex in yeast. Activation of transcription by indole compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

A human aryl hydrocarbon receptor signaling pathway constructed in yeast displays additive responses to ligand mixtures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Development of a green fluorescent protein-based cell bioassay for the rapid and inexpensive detection and characterization of ah receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Evidence that murine preimplantation embryos express aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Distribution of mRNAs encoding the arylhydrocarbon receptor, arylhydrocarbon receptor nuclear translocator, and arylhydrocarbon receptor nuclear translocator-2 in the rat brain and brainstem.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

A model for recognition of polychlorinated dibenzo-p-dioxins by the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

The presence of genotoxic and bioactive components in indigo dyed fabrics--a possible health risk?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Aryl hydrocarbon receptor-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Molecular biology of the Ah receptor and its role in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

The t(1;12)(q21;p13) translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

A ligand for the aryl hydrocarbon receptor isolated from lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Regulation of CYP1A1 transcription via the metabolism of the tryptophan-derived 6-formylindolo[3,2-b]carbazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Complementation of Ah receptor deficiency in hepatoma cells: negative feedback regulation and cell cycle control by the Ah receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Indirubin and meisoindigo in the treatment of chronic myelogenous leukemia in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Aryl hydrocarbon receptor mediates benzene-induced hematotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

Recruitment of dioxin receptor to active transcription sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

7 January 2021

Possible involvement of aryl hydrocarbon receptor (AhR) in adult T-cell leukemia (ATL) leukemogenesis: constitutive activation of AhR in ATL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

7 January 2021

Xenobiotic response element binding enriched in both nuclear and microsomal fractions of rat cerebellum.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

7 January 2021

Purification of GSK-3 by affinity chromatography on immobilized axin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

7 January 2021

Cell-specific regulation of human aryl hydrocarbon receptor expression by transforming growth factor-beta(1).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207535

7 January 2021

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1038/SJ.ONC.1207535

Identifiers

DOI

10.1038/SJ.ONC.1207535

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Dimensions Publication ID

21 September 2017

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1 reference