Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients (Q40560199)

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scientific article published on May 1, 2003

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English	Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients	scientific article published on May 1, 2003

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scholarly article

1 reference

Europe PubMed Central

21 September 2017

Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients (English)

1 reference

Europe PubMed Central

21 September 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

molecular medicine

1 reference

10.1038/SJ.CGT.7700585

https://api.crossref.org/works/10.1038/SJ.CGT.7700585

28 December 2023

John Nemunaitis

1

object named as

John Nemunaitis

1 reference

Europe PubMed Central

21 September 2017

George G. Netto

5

object named as

George Netto

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719704

28 December 2023

author name string

Casey Cunningham

2

1 reference

Europe PubMed Central

21 September 2017

Leonard Post

4

1 reference

Europe PubMed Central

21 September 2017

Dawn Rich

7

1 reference

Europe PubMed Central

21 September 2017

Angela Blackburn

8

1 reference

Europe PubMed Central

21 September 2017

Beverly Sands

9

1 reference

Europe PubMed Central

21 September 2017

Brenda Gibson

10

1 reference

Europe PubMed Central

21 September 2017

Britta Randlev

11

1 reference

Europe PubMed Central

21 September 2017

Scott Freeman

12

1 reference

Europe PubMed Central

21 September 2017

Alex W. Tong

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719704

28 December 2023

A. Scott Paulson

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12719704

28 December 2023

language of work or name

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12719704

28 December 2023

publication date

1 May 2003

1 reference

Europe PubMed Central

21 September 2017

full work available at URL

https://www.nature.com/articles/7700585

1 reference

10.1038/SJ.CGT.7700585

https://api.crossref.org/works/10.1038/SJ.CGT.7700585

28 December 2023

https://www.nature.com/articles/7700585.pdf

Portable Document Format

1 reference

10.1038/SJ.CGT.7700585

https://api.crossref.org/works/10.1038/SJ.CGT.7700585

28 December 2023

Cancer Gene Therapy

1 reference

Europe PubMed Central

21 September 2017

10

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Europe PubMed Central

21 September 2017

341-352

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Europe PubMed Central

21 September 2017

5

1 reference

Europe PubMed Central

21 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700585

0 references

Replication-selective adenoviruses as oncolytic agents

1 reference

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21 January 2018

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

1 reference

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21 January 2018

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

1 reference

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21 January 2018

Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer

1 reference

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21 January 2018

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

1 reference

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21 January 2018

Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity

1 reference

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21 January 2018

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

1 reference

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21 January 2018

Effects of liposome-encapsulated dichloromethylene diphosphonate on macrophage function and endotoxin-induced mortality.

1 reference

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21 January 2018

The liposome-mediated macrophage 'suicide' technique

1 reference

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21 January 2018

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

1 reference

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Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectors

1 reference

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Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle

1 reference

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Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

1 reference

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21 January 2018

Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration

1 reference

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Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression

1 reference

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21 January 2018

Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung.

1 reference

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21 January 2018

Anti-T cell receptor monoclonal antibody prolongs transgene expression following adenovirus-mediated in vivo gene transfer to mouse synovium.

1 reference

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21 January 2018

Suppression of the immune response to an adenovirus vector and enhancement of intratumoral transgene expression by low-dose etoposide

1 reference

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21 January 2018

Gene therapy for hemophilia B: host immunosuppression prolongs the therapeutic effect of adenovirus-mediated factor IX expression

1 reference

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21 January 2018

Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver

1 reference

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21 January 2018

FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer

1 reference

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21 January 2018

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700585

21 January 2018

Role of adenovirus antigens in the induction of virus neutralizing antibody

1 reference

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21 January 2018

Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo

1 reference

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21 January 2018

MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses.

1 reference

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21 January 2018

Adenovirus proteins that subvert host defenses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700585

21 January 2018

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700585

21 January 2018

Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700585

21 January 2018

Toxicological comparison of E2a-deleted and first-generation adenoviral vectors expressing alpha1-antitrypsin after systemic delivery

1 reference

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21 January 2018

Viral mechanisms of immune evasion

1 reference

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Ectromelia, vaccinia and cowpox viruses encode secreted interleukin-18-binding proteins

1 reference

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21 January 2018

One step ahead of the game: viral immunomodulatory molecules

1 reference

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CrmE, a novel soluble tumor necrosis factor receptor encoded by poxviruses.

1 reference

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21 January 2018

Immune evasion by adenoviruses

1 reference

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21 January 2018

Vaccinia virus homologues of the Shope fibroma virus inverted terminal repeat proteins and a discontinuous ORF related to the tumor necrosis factor receptor family

1 reference

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21 January 2018

T2 open reading frame from the Shope fibroma virus encodes a soluble form of the TNF receptor

1 reference

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21 January 2018

Myxoma virus expresses a secreted protein with homology to the tumor necrosis factor receptor gene family that contributes to viral virulence

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21 January 2018

Phase I trial of intravenous administration of PV701, an oncolytic virus, in patients with advanced solid cancers

1 reference

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21 January 2018

Gene delivery from the E3 region of replicating human adenovirus: evaluation of the 6.7 K/gp19 K region

1 reference

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A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

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21 January 2018

Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents

1 reference

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21 January 2018

Immunosuppression by FK506 markedly prolongs expression of adenovirus-delivered transgene in skeletal muscles of adult dystrophic [mdx] mice

1 reference

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21 January 2018

Intra-arterial delivery of a recombinant adenovirus does not increase gene transfer to tumor cells in a rat model of metastatic colorectal carcinoma

1 reference

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7 January 2021

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Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ

1 reference

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7 January 2021

based on heuristic

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Selective Depletion of Liver and Splenic Macrophages Using Liposomes Encapsulating the Drug Dichloromethylene Diphosphonate: Effects on Antimicrobial Resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700585

7 January 2021

based on heuristic

inferred from DOI database lookup

Macrophage subset repopulation in the spleen: differential kinetics after liposome-mediated elimination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700585

7 January 2021

based on heuristic

inferred from DOI database lookup

Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700585

7 January 2021

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Kupffer cell elimination enhances development of liver schizonts of Plasmodium berghei in rats.

1 reference

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7 January 2021

based on heuristic

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Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis

1 reference

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7 January 2021

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Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses

1 reference

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7 January 2021

based on heuristic

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Use of transient CD4 lymphocyte depletion to prolong transgene expression of E1-deleted adenoviral vectors

1 reference

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7 January 2021

based on heuristic

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Cytotoxic T-lymphocyte target proteins and their major histocompatibility complex class I restriction in response to adenovirus vectors delivered to mouse liver.

1 reference

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7 January 2021

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Neutralization of adenoviruses: kinetics, stoichiometry, and mechanisms

1 reference

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7 January 2021

based on heuristic

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Stepwise dismantling of adenovirus 2 during entry into cells

1 reference

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7 January 2021

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Vitronectin receptor antibodies inhibit infection of HeLa and A549 cells by adenovirus type 12 but not by adenovirus type 2.

1 reference

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7 January 2021

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Persistence of Replication-Deficient Adenovirus-Mediated Gene Transfer in Lungs of Immune-Deficient (nu/nu) Mice

1 reference

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7 January 2021

based on heuristic

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Immunomodulation by viruses: the myxoma virus story

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Vaccinia virus immune evasion

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer Research

3

59

2623

author name string

C Heise

publication date

1999

1 reference

10.1038/SJ.CGT.7700585

https://api.crossref.org/works/10.1038/SJ.CGT.7700585

28 December 2023

Cancer Research

5

54

2287

author name string

T Fujiwara

publication date

1994

1 reference

10.1038/SJ.CGT.7700585

https://api.crossref.org/works/10.1038/SJ.CGT.7700585

28 December 2023

Cancer Research

6

60

1009

author name string

L You

publication date

2000

1 reference

10.1038/SJ.CGT.7700585

https://api.crossref.org/works/10.1038/SJ.CGT.7700585

28 December 2023

Cancer Research

9

60

6359

author name string

J Nemunaitis

publication date

2000

1 reference

10.1038/SJ.CGT.7700585

https://api.crossref.org/works/10.1038/SJ.CGT.7700585

28 December 2023

Cancer Research

32

54

4355

author name string

BH Long

publication date

1994

1 reference

10.1038/SJ.CGT.7700585

https://api.crossref.org/works/10.1038/SJ.CGT.7700585

28 December 2023

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10.1038/SJ.CGT.7700585

1 reference

Europe PubMed Central

21 September 2017

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0 references

1 reference

Europe PubMed Central

21 September 2017

ResearchGate publication ID

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