The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts (Q40558019)

21 September 2017

The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts (English)

1 reference

21 September 2017

1 reference

Yann Percherancier

3

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Nathalie Sol-Foulon

Nathalie Sol-Foulon

1

0 references

Françoise Bachelerie

Françoise Bachelerie

6

0 references

Olivier Schwartz

Olivier Schwartz

7

0 references

Françoise Porrot

4

Françoise Porrot

1 reference

21 September 2017

Cécile Esnault

2

1 reference

PubMed ID

15133044

21 September 2017

Patricia Metais-Cunha

5

1 reference

PubMed ID

15133044

21 September 2017

language of work or name

English

0 references

publication date

7 May 2004

1 reference

Journal of Biological Chemistry

21 September 2017

1 reference

21 September 2017

279

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21 September 2017

30

1 reference

21 September 2017

31398-31408

1 reference

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

In vivo analysis of Nef function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Live and let die: Nef functions beyond HIV replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Human immunodeficiency virus type 1 Nef mediates sustained membrane expression of tumor necrosis factor and the related cytokine LIGHT on activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 Nef impairs MHC class II antigen presentation and surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Mechanism for down-regulation of CD28 by Nef.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 Nef-Induced Upregulation of DC-SIGN in Dendritic Cells Promotes Lymphocyte Clustering and Viral Spread

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Nef-mediated clathrin-coated pit formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Nef proteins encoded by human and simian immunodeficiency viruses induce the accumulation of endosomes and lysosomes in human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Nef does not affect the efficiency of human immunodeficiency virus type 1 fusion with target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 Nef and host cell protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

The Nef protein of HIV-1 associates with rafts and primes T cells for activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Lipid rafts and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Lipid rafts and assembly of enveloped viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Virus entry, assembly, budding, and membrane rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Do lipid rafts mediate virus assembly and pseudotyping?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Cholesterol depletion of human immunodeficiency virus type 1 and simian immunodeficiency virus with beta-cyclodextrin inactivates and permeabilizes the virions: evidence for virion-associated lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV-1 entry into T-cells is not dependent on CD4 and CCR5 localization to sphingolipid-enriched, detergent-resistant, raft membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

CD4 receptor localized to non-raft membrane microdomains supports HIV-1 entry. Identification of a novel raft localization marker in CD4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Plasma membrane rafts play a critical role in HIV-1 assembly and release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Multimerization of human immunodeficiency virus type 1 Gag promotes its localization to barges, raft-like membrane microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Human immunodeficiency virus type 1 assembly and lipid rafts: Pr55(gag) associates with membrane domains that are largely resistant to Brij98 but sensitive to Triton X-100

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Independent segregation of human immunodeficiency virus type 1 Gag protein complexes and lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Palmitoylation of the HIV-1 envelope glycoprotein is critical for viral infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Role for human immunodeficiency virus type 1 membrane cholesterol in viral internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Nef increases infectivity of HIV via lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

The on-off story of protein palmitoylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Subcellular localization of herpes simplex virus type 1 UL51 protein and role of palmitoylation in Golgi apparatus targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Palmitoylation of the murine leukemia virus envelope protein is critical for lipid raft association and surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Palmitoylation of the Rous sarcoma virus transmembrane glycoprotein is required for protein stability and virus infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Protein palmitoylation: a regulator of neuronal development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

The human and simian immunodeficiency virus envelope glycoprotein transmembrane subunits are palmitoylated

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

New insights into the mechanisms of protein palmitoylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Binding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Nef is required for efficient HIV-1 replication in cocultures of dendritic cells and lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

An alternative way of CD4 and CD8 association with protein kinases of the Src family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

CD40 signaling in human dendritic cells is initiated within membrane rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Functional roles for fatty acylated amino-terminal domains in subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Human immunodeficiency virus type 1 Nef activates p21-activated kinase via recruitment into lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Intrinsic signals in the unique domain target p56(lck) to the plasma membrane independently of CD4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Palmitoylation of CCR5 is critical for receptor trafficking and efficient activation of intracellular signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Palmitoylation-dependent control of degradation, life span, and membrane expression of the CCR5 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Distinct mechanisms of agonist-induced endocytosis for human chemokine receptors CCR5 and CXCR4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

Lipid rafts and pseudotyping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401621200

21 January 2018

Identifiers

DOI

10.1074/JBC.M401621200

1 reference

21 September 2017

1 reference

PubMed ID

15133044