BRCA1 can modulate RNA polymerase II carboxy-terminal domain phosphorylation levels (Q40530491)

21 September 2017

BRCA1 can modulate RNA polymerase II carboxy-terminal domain phosphorylation levels (English)

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21 September 2017

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Annie Moisan

1

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21 September 2017

Chantal Larochelle

series ordinal

2

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21 September 2017

Benoît Guillemette

series ordinal

3

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21 September 2017

Luc Gaudreau

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4

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21 September 2017

language of work or name

English

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publication date

1 August 2004

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Molecular and Cellular Biology

21 September 2017

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21 September 2017

24

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21 September 2017

16

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21 September 2017

6947-6956

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describes a project that uses

21 September 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC479726/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability.

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The BRCT Domain Is a Phospho-Protein Binding Domain

22 September 2017

1 reference

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BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

22 September 2017

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BRCA1 Associates with Processive RNA Polymerase II

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

BRCA1 and p53: compensatory roles in DNA repair

22 September 2017

1 reference

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A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3' end processing.

22 September 2017

1 reference

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Breast cancer gene 1 (BRCA1): role in cell cycle regulation and DNA repair--perhaps through transcription

22 September 2017

1 reference

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MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions

22 September 2017

1 reference

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BRCA1 transcriptionally regulates genes involved in breast tumorigenesis

22 September 2017

1 reference

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cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos

22 September 2017

1 reference

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Regulation of RNA polymerase II activity by CTD phosphorylation and cell cycle control

22 September 2017

1 reference

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Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Direct DNA binding by Brca1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Mechanism of transcription initiation and promoter escape by RNA polymerase II.

22 September 2017

1 reference

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Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop

22 September 2017

1 reference

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Transcription of eukaryotic protein-coding genes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Roles of BRCA1 and its interacting proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Heat shock protein 70 and ATP as partners in cell homeostasis (Review).

22 September 2017

1 reference

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Conserved BRCT regions of TopBP1 and of the tumor suppressor BRCA1 bind strand breaks and termini of DNA

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Casein kinase 2 binds to and phosphorylates BRCA1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Chromatin remodeling and activation of chromosomal DNA replication by an acidic transcriptional activation domain from BRCA1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

CDK inhibition and cancer therapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Cyclin C/CDK8 and cyclin H/CDK7/p36 are biochemically distinct CTD kinases

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

The molecular mechanism of mitotic inhibition of TFIIH is mediated by phosphorylation of CDK7.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

BRCA1 is a component of the RNA polymerase II holoenzyme

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Regulation of CDK7 substrate specificity by MAT1 and TFIIH.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Transcriptional activation by recruitment

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Evidence for a transcriptional activation function of BRCA1 C-terminal region

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

UV-induced ubiquitination of RNA polymerase II: a novel modification deficient in Cockayne syndrome cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Three functional classes of transcriptional activation domain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

CAK, the p34cdc2 activating kinase, contains a protein identical or closely related to p40MO15.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Analysis of the role of TFIIE in basal transcription and TFIIH-mediated carboxy-terminal domain phosphorylation through structure-function studies of TFIIE-alpha

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Requirement for TFIIH kinase activity in transcription by RNA polymerase II

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Ultraviolet radiation-induced ubiquitination and proteasomal degradation of the large subunit of RNA polymerase II. Implications for transcription-coupled DNA repair

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Phosphorylation of mammalian RNA polymerase II.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

BRCA1 can stimulate gene transcription by a unique mechanism

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Purification of P-TEFb, a transcription factor required for the transition into productive elongation.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Analyzing JNK and p38 mitogen-activated protein kinase activity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=479726

BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression

20 August 2018

1 reference

12 December 2020

A transcription reinitiation intermediate that is stabilized by activator

1 reference

12 December 2020

Phosphorylation causes a conformational change in the carboxyl-terminal domain of the mouse RNA polymerase II largest subunit

1 reference

12 December 2020

Transcriptional activation by BRCA1

1 reference

12 December 2020

Activation of transcription in vitro by the BRCA1 carboxyl-terminal domain

1 reference

12 December 2020

The cycling of RNA polymerase II during transcription

1 reference

12 December 2020

Mechanism of Cdk2/Cyclin E inhibition by p27 and p27 phosphorylation

1 reference

12 December 2020

BRCA1 is a selective co-activator of 14-3-3 sigma gene transcription in mouse embryonic stem cells

1 reference

12 December 2020

BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1)

1 reference

12 December 2020

Participation of BRCA1 in the DNA repair response...via transcription

1 reference

12 December 2020

Mutations in the BRCT domain confer temperature sensitivity to BRCA1 in transcription activation

1 reference

12 December 2020

10.1128/MCB.24.16.6947-6956.2004

Identifiers

DOI

1 reference

21 September 2017

1 reference

21 September 2017

PubMed publication ID

15282296

1 reference